Antidepressants and Depression Treatment

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Which type of 5HT receptors is responsible for the therapeutic effects of SSRIs?

5HT1A (correct)

5HT3 and 5HT4

5HT6 and 5HT7

5HT2A and 5HT2C

What is the primary factor in selecting an antidepressant drug?

Indication for the medication (correct)

Availability of the medication

Cost of the medication

Potential drug interactions

What is the most common adverse effect of SSRIs?

Nausea (correct)

Loss of libido

Anorgasmia

Weight gain

Which of the following conditions is NOT typically treated with antipsychotic drugs?

Nonpsychotic anxiety disorder Signup and view all the answers

What is the primary mechanism of action of SSRIs?

Agonist action on 5HT1A receptors Signup and view all the answers

What is the primary route of excretion for SSRIs?

Renal Signup and view all the answers

What is the primary goal of using antidepressant drugs in the treatment of depression?

To alleviate the symptoms of depression Signup and view all the answers

Which type of antidepressant is chemically diverse and specifically inhibits serotonin reuptake?

Selective serotonin reuptake inhibitors (SSRIs) Signup and view all the answers

What is a common adverse effect of tricyclic antidepressants (TCAs) due to the block of muscarinic receptors?

Dry mouth Signup and view all the answers

What is the mechanism by which tricyclic antidepressants (TCAs) increase the concentration of monoamines in the synaptic cleft?

By inhibiting the reuptake of serotonin and norepinephrine Signup and view all the answers

How do tricyclic antidepressants (TCAs) compare to selective serotonin reuptake inhibitors (SSRIs) in terms of safety in overdose?

SSRIs are safer in overdose than TCAs Signup and view all the answers

What is the primary route of excretion for tricyclic antidepressants (TCAs)?

Renal Signup and view all the answers

What is the estimated percentage of the population affected by schizophrenia?

1% Signup and view all the answers

What is the primary goal of pharmacological treatment of psychoses?

To eliminate the symptoms of the disease Signup and view all the answers

What is the term for the disruption to normal emotions and behaviors in schizophrenia?

Negative symptoms Signup and view all the answers

What is the neurochemical basis of positive symptoms in schizophrenia?

Overactivity of mesolimbic dopamine receptors Signup and view all the answers

What is the term for the classification of antipsychotic drugs that are first-generation?

Typical Signup and view all the answers

What is the approximate age range when schizophrenia most commonly has its onset?

Late adolescence to early adulthood Signup and view all the answers

Which type of antipsychotic drugs are known to ameliorate both positive and negative symptoms of schizophrenia?

Atypical antipsychotic drugs Signup and view all the answers

What is the primary mechanism of action of antipsychotic drugs in reducing symptoms of schizophrenia?

Blocking of D2 dopamine receptors Signup and view all the answers

Which of the following side effects is commonly associated with conventional antipsychotic drugs?

Extrapyramidal side effects Signup and view all the answers

What is the primary difference between typical and atypical antipsychotic drugs?

Side effect profile Signup and view all the answers

Which of the following is a long-term side effect of conventional antipsychotic drugs?

Tardive dyskinesias Signup and view all the answers

What is the reason for the endocrine side effects of antipsychotic drugs?

Increased prolactin release Signup and view all the answers

What is the primary consideration for choosing an antipsychotic drug?

Differences in adverse effects and efficacy Signup and view all the answers

Which of the following antipsychotic drugs is known to cause bone marrow suppression?

Clozapine Signup and view all the answers

What is the approximate percentage of patients who do not respond to antipsychotic drugs?

20% Signup and view all the answers

How do slow-release preparations of antipsychotic drugs work?

They act for a longer duration, typically 2-4 weeks Signup and view all the answers

What is the primary route of administration for antipsychotic drugs?

Oral administration Signup and view all the answers

What is the main organ responsible for the metabolism of antipsychotic drugs?

Liver Signup and view all the answers