30 Questions
Which type of 5HT receptors is responsible for the therapeutic effects of SSRIs?
5HT1A
What is the primary factor in selecting an antidepressant drug?
Indication for the medication
What is the most common adverse effect of SSRIs?
Nausea
Which of the following conditions is NOT typically treated with antipsychotic drugs?
Nonpsychotic anxiety disorder
What is the primary mechanism of action of SSRIs?
Agonist action on 5HT1A receptors
What is the primary route of excretion for SSRIs?
Renal
What is the primary goal of using antidepressant drugs in the treatment of depression?
To alleviate the symptoms of depression
Which type of antidepressant is chemically diverse and specifically inhibits serotonin reuptake?
Selective serotonin reuptake inhibitors (SSRIs)
What is a common adverse effect of tricyclic antidepressants (TCAs) due to the block of muscarinic receptors?
Dry mouth
What is the mechanism by which tricyclic antidepressants (TCAs) increase the concentration of monoamines in the synaptic cleft?
By inhibiting the reuptake of serotonin and norepinephrine
How do tricyclic antidepressants (TCAs) compare to selective serotonin reuptake inhibitors (SSRIs) in terms of safety in overdose?
SSRIs are safer in overdose than TCAs
What is the primary route of excretion for tricyclic antidepressants (TCAs)?
Renal
What is the estimated percentage of the population affected by schizophrenia?
1%
What is the primary goal of pharmacological treatment of psychoses?
To eliminate the symptoms of the disease
What is the term for the disruption to normal emotions and behaviors in schizophrenia?
Negative symptoms
What is the neurochemical basis of positive symptoms in schizophrenia?
Overactivity of mesolimbic dopamine receptors
What is the term for the classification of antipsychotic drugs that are first-generation?
Typical
What is the approximate age range when schizophrenia most commonly has its onset?
Late adolescence to early adulthood
Which type of antipsychotic drugs are known to ameliorate both positive and negative symptoms of schizophrenia?
Atypical antipsychotic drugs
What is the primary mechanism of action of antipsychotic drugs in reducing symptoms of schizophrenia?
Blocking of D2 dopamine receptors
Which of the following side effects is commonly associated with conventional antipsychotic drugs?
Extrapyramidal side effects
What is the primary difference between typical and atypical antipsychotic drugs?
Side effect profile
Which of the following is a long-term side effect of conventional antipsychotic drugs?
Tardive dyskinesias
What is the reason for the endocrine side effects of antipsychotic drugs?
Increased prolactin release
What is the primary consideration for choosing an antipsychotic drug?
Differences in adverse effects and efficacy
Which of the following antipsychotic drugs is known to cause bone marrow suppression?
Clozapine
What is the approximate percentage of patients who do not respond to antipsychotic drugs?
20%
How do slow-release preparations of antipsychotic drugs work?
They act for a longer duration, typically 2-4 weeks
What is the primary route of administration for antipsychotic drugs?
Oral administration
What is the main organ responsible for the metabolism of antipsychotic drugs?
Liver
Test your knowledge about antidepressant drugs, their effects on the brain, and their classification. Learn about the different types of antidepressants, including tricyclic antidepressants, selective serotonin reuptake inhibitors, and more.
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