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Dentistry: Hypoxia and Cyanosis
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Dentistry: Hypoxia and Cyanosis

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Questions and Answers

What is the primary consequence of hypoxemic hypoxia?

  • Decreased oxygen content in arterial blood (correct)
  • Increased partial pressure of O2 in inspired air
  • Increased affinity of Hb to O2
  • Increased oxygen content in arterial blood
  • Which of the following is a cause of anemic hypoxia?

  • Morphine-induced RC depression
  • Atrial septal defect
  • Iron deficiency (correct)
  • Interstitial pulmonary fibrosis
  • What is the primary mechanism of CO poisoning in inducing hypoxia?

  • Decreasing the partial pressure of O2 in inspired air
  • Inhibiting the diffusion of oxygen across the respiratory membrane
  • Increasing the affinity of Hb to O2 (correct)
  • Reducing oxygen content in arterial blood
  • Which type of hypoxia is characterized by inadequate blood flow to the tissues?

    <p>Stagnant hypoxia</p> Signup and view all the answers

    What is the primary consequence of stagnant hypoxia?

    <p>Inadequate oxygen delivery to the tissues</p> Signup and view all the answers

    Which of the following is a cause of hypoxemic hypoxia?

    <p>Morphine-induced RC depression</p> Signup and view all the answers

    What is the primary difference between hypoxemic and anemic hypoxia?

    <p>PaO2 is decreased in hypoxemic hypoxia, but normal in anemic hypoxia</p> Signup and view all the answers

    Which type of hypoxia is characterized by a diffusion defect in the respiratory membrane?

    <p>Hypoxemic hypoxia</p> Signup and view all the answers

    What effect does slow blood flow have in stagnant hypoxia?

    <p>It increases the withdrawal of O2 from blood in capillaries</p> Signup and view all the answers

    Why is O2 therapy not beneficial in anemic hypoxia?

    <p>Because the defect is in the hemoglobin, not the O2 levels</p> Signup and view all the answers

    What does an increase in reduced hemoglobin levels in blood cause?

    <p>Cyanosis</p> Signup and view all the answers

    Which of the following conditions leads to the inability of tissues to utilize O2?

    <p>Histotoxic hypoxia</p> Signup and view all the answers

    Which symptom is most likely to occur first in moderate hypoxia affecting the brain?

    <p>Mental aberration</p> Signup and view all the answers

    Why is the PaO2 and O2 content normal in histotoxic hypoxia?

    <p>Because the tissues cannot utilize O2 due to a toxic substance</p> Signup and view all the answers

    What is the threshold amount of reduced Hb that leads to cyanosis?

    <p>5 gm reduced Hb/100 ml blood</p> Signup and view all the answers

    Which of the following is not an effect of moderate hypoxia on the brain?

    <p>Loss of consciousness</p> Signup and view all the answers

    Study Notes

    Hypoxia

    • Hypoxia is defined as O2 deficiency at the tissue level.
    • Types of hypoxia include:
      • Hypoxemic hypoxia: decreased PaO2 in arterial blood, causing decreased O2 content.
      • Anemic hypoxia: normal PaO2, but reduced amount of Hb that carries O2.
      • Stagnant hypoxia: slow blood flow to tissues, leading to inadequate O2 delivery.
      • Histotoxic hypoxia: tissues unable to utilize O2 due to toxic substances.
    • Causes of hypoxemic hypoxia:
      • Decreased partial pressure of O2 in inspired air.
      • Intracardiac shunt (right to left shunt).
      • Pulmonary diseases (hypoventilation, diffusion defect).
    • Causes of anemic hypoxia:
      • Anemia (deficiency of essential nutrients like iron).
      • CO poisoning (formation of carboxyhemoglobin).
    • Effects of hypoxia:
      • Increased rate of ventilation.
      • Mental aberration, impaired judgment, drowsiness, excitement, disorientation, loss of time sense, and headache.
      • Anorexia, nausea, vomiting, tachycardia, and hypertension.
      • Loss of consciousness in severe cases (PO2 < 20 mmHg).

    Cyanosis

    • Defined as a bluish discoloration of skin and mucous membrane due to abnormal increase in reduced Hb in blood.
    • Threshold of cyanosis: 5 gm reduced Hb/100 ml blood.
    • Types of hypoxia with cyanosis:
      • Hypoxemic hypoxia.
      • Anemic hypoxia.
    • Effectiveness of O2 therapy in treatment of hypoxia:
      • Useful in hypoxemic hypoxia.
      • Not useful in anemic, stagnant, or histotoxic hypoxia.

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    Description

    Learn about hypoxia, its types, causes, and effects, as well as cyanosis, its threshold, and types with and without cyanosis. Undergraduate-level dentistry lecture.

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