Dengue Virus and Disease Overview
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Questions and Answers

What is the typical incubation period for dengue?

  • 3-5 days
  • 7-10 days
  • 5-7 days (correct)
  • 2-4 days

    • What is the main reason for the resurgence of dengue in the 1980s?

  • Increased international travel
  • Emergence of new dengue serotypes
  • Deterioration of public health infrastructure
  • All of the above (correct)

    • What percentage of dengue infections are symptomatic?

  • 15%
  • 10%
  • 20%
  • 25% (correct)

    • Which clinical classification did the WHO replace in 2009?

    <p>Dengue and Dengue Hemorrhagic Fever/Dengue Shock Syndrome</p> Signup and view all the answers

    What is the duration of the febrile phase in dengue?

    <p>2-7 days</p> Signup and view all the answers

    Which of the following is NOT a contributing factor to the resurgence of dengue?

    <p>Improved public health infrastructure</p> Signup and view all the answers

    What is the main way that dengue viruses are spread to people?

    <p>Through the bite of an infected Aedes mosquito</p> Signup and view all the answers

    What percentage of the world's population lives in areas at risk of dengue?

    <p>50%</p> Signup and view all the answers

    What is the estimated number of deaths from severe dengue each year?

    <p>40,000</p> Signup and view all the answers

    How many different dengue virus serotypes are there?

    <p>4</p> Signup and view all the answers

    Which of the following statements about the release of dengue virus is most accurate?

    <p>Some dengue virus is released as fully mature membrane protein and can reinfect other cells, while some is released with immature membrane protein and cannot infect other cells.</p> Signup and view all the answers

    When were the first reported epidemics of dengue?

    <p>1779-1780</p> Signup and view all the answers

    What is a common laboratory finding in dengue fever during the acute phase?

    <p>Thrombocytopenia</p> Signup and view all the answers

    Which diagnostic test would be most appropriate for detecting dengue virus in the acute phase (≤7 days after symptom onset)?

    <p>Dengue virus antigen detection (NS1)</p> Signup and view all the answers

    What is a common symptom during the convalescent phase of dengue fever?

    <p>Itchy, flaking rash</p> Signup and view all the answers

    Which of the following specimen types would be appropriate for molecular testing (RT-PCR) for dengue virus?

    <p>Serum</p> Signup and view all the answers

    What is a common hemodynamic change observed as a patient's well-being improves during dengue fever?

    <p>Bradycardia</p> Signup and view all the answers

    Which of the following laboratory findings is NOT commonly associated with dengue fever?

    <p>Hypocalcemia</p> Signup and view all the answers

    What is the recommended treatment for fever in dengue patients?

    <p>Acetaminophen and tepid sponge baths</p> Signup and view all the answers

    Why should dengue patients avoid mosquito bites?

    <p>To reduce the risk of further transmission</p> Signup and view all the answers

    What is the recommended treatment for fluid loss due to capillary leakage in dengue patients?

    <p>Intravenous fluids and monitoring hematocrit levels</p> Signup and view all the answers

    What is the reason why prophylactic platelet transfusions are not recommended for dengue patients?

    <p>They can contribute to fluid overload</p> Signup and view all the answers

    What is the key difference between the two dengue vaccines mentioned in the text?

    <p>DengVaxia requires 3 doses, while QDenga requires 2 doses.</p> Signup and view all the answers

    What is the key caution regarding the use of the DengVaxia vaccine?

    <p>It may increase the risk of severe dengue if administered to seronegative individuals.</p> Signup and view all the answers

    What is the main purpose of Nucleic Acid Amplification Testing (NAAT) for dengue?

    <p>Confirm dengue infection</p> Signup and view all the answers

    Which statement about Dengue Virus Antigen Detection using NS1 is accurate?

    <p>NS1 is secreted into the blood during dengue infection</p> Signup and view all the answers

    In Dengue diagnosis, what is the role of IgM antibody testing when used alongside NAAT or NS1 detection?

    <p>Confirms dengue infection</p> Signup and view all the answers

    Why is Tissue testing for dengue virus not considered an immediate diagnostic tool?

    <p>It requires a biopsy or autopsy specimen</p> Signup and view all the answers

    Which statement about IgM Antibody ELISA in Dengue diagnosis is correct?

    <p>It can cross-react with other unrelated viruses</p> Signup and view all the answers

    Why is there no specific antiviral treatment for dengue?

    <p>Because of the rapid mutation rate of the DENV serotypes</p> Signup and view all the answers

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