Dengue Virus and Disease Overview
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Questions and Answers

What is the typical incubation period for dengue?

  • 3-5 days
  • 7-10 days
  • 5-7 days (correct)
  • 2-4 days

What is the main reason for the resurgence of dengue in the 1980s?

  • Increased international travel
  • Emergence of new dengue serotypes
  • Deterioration of public health infrastructure
  • All of the above (correct)

What percentage of dengue infections are symptomatic?

  • 15%
  • 10%
  • 20%
  • 25% (correct)

Which clinical classification did the WHO replace in 2009?

<p>Dengue and Dengue Hemorrhagic Fever/Dengue Shock Syndrome (C)</p> Signup and view all the answers

What is the duration of the febrile phase in dengue?

<p>2-7 days (B)</p> Signup and view all the answers

Which of the following is NOT a contributing factor to the resurgence of dengue?

<p>Improved public health infrastructure (D)</p> Signup and view all the answers

What is the main way that dengue viruses are spread to people?

<p>Through the bite of an infected Aedes mosquito (C)</p> Signup and view all the answers

What percentage of the world's population lives in areas at risk of dengue?

<p>50% (A)</p> Signup and view all the answers

What is the estimated number of deaths from severe dengue each year?

<p>40,000 (A)</p> Signup and view all the answers

How many different dengue virus serotypes are there?

<p>4 (A)</p> Signup and view all the answers

Which of the following statements about the release of dengue virus is most accurate?

<p>Some dengue virus is released as fully mature membrane protein and can reinfect other cells, while some is released with immature membrane protein and cannot infect other cells. (D)</p> Signup and view all the answers

When were the first reported epidemics of dengue?

<p>1779-1780 (B)</p> Signup and view all the answers

What is a common laboratory finding in dengue fever during the acute phase?

<p>Thrombocytopenia (A)</p> Signup and view all the answers

Which diagnostic test would be most appropriate for detecting dengue virus in the acute phase (≤7 days after symptom onset)?

<p>Dengue virus antigen detection (NS1) (A)</p> Signup and view all the answers

What is a common symptom during the convalescent phase of dengue fever?

<p>Itchy, flaking rash (A)</p> Signup and view all the answers

Which of the following specimen types would be appropriate for molecular testing (RT-PCR) for dengue virus?

<p>Serum (D)</p> Signup and view all the answers

What is a common hemodynamic change observed as a patient's well-being improves during dengue fever?

<p>Bradycardia (D)</p> Signup and view all the answers

Which of the following laboratory findings is NOT commonly associated with dengue fever?

<p>Hypocalcemia (B)</p> Signup and view all the answers

What is the recommended treatment for fever in dengue patients?

<p>Acetaminophen and tepid sponge baths (D)</p> Signup and view all the answers

Why should dengue patients avoid mosquito bites?

<p>To reduce the risk of further transmission (C)</p> Signup and view all the answers

What is the recommended treatment for fluid loss due to capillary leakage in dengue patients?

<p>Intravenous fluids and monitoring hematocrit levels (B)</p> Signup and view all the answers

What is the reason why prophylactic platelet transfusions are not recommended for dengue patients?

<p>They can contribute to fluid overload (B)</p> Signup and view all the answers

What is the key difference between the two dengue vaccines mentioned in the text?

<p>DengVaxia requires 3 doses, while QDenga requires 2 doses. (D)</p> Signup and view all the answers

What is the key caution regarding the use of the DengVaxia vaccine?

<p>It may increase the risk of severe dengue if administered to seronegative individuals. (B)</p> Signup and view all the answers

What is the main purpose of Nucleic Acid Amplification Testing (NAAT) for dengue?

<p>Confirm dengue infection (D)</p> Signup and view all the answers

Which statement about Dengue Virus Antigen Detection using NS1 is accurate?

<p>NS1 is secreted into the blood during dengue infection (B)</p> Signup and view all the answers

In Dengue diagnosis, what is the role of IgM antibody testing when used alongside NAAT or NS1 detection?

<p>Confirms dengue infection (B)</p> Signup and view all the answers

Why is Tissue testing for dengue virus not considered an immediate diagnostic tool?

<p>It requires a biopsy or autopsy specimen (A)</p> Signup and view all the answers

Which statement about IgM Antibody ELISA in Dengue diagnosis is correct?

<p>It can cross-react with other unrelated viruses (A)</p> Signup and view all the answers

Why is there no specific antiviral treatment for dengue?

<p>Because of the rapid mutation rate of the DENV serotypes (A)</p> Signup and view all the answers

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