Podcast
Questions and Answers
What is the main function of dendritic cells once they are in the lymph node?
What is the main function of dendritic cells once they are in the lymph node?
- Phagocytose antigens
- Secrete cytokines
- Activate naïve T cells (correct)
- Activate B cells
Which of the following is NOT one of the 3 SIGNALS needed for T cell differentiation from naive to effector cells?
Which of the following is NOT one of the 3 SIGNALS needed for T cell differentiation from naive to effector cells?
- Peptide and MHC molecule with specific TCR
- PD-1 receptors (correct)
- B7.1 + B7.2 and CD28 molecules
- Cytokines
What happens to the expression of pattern recognition receptors (PRRs) in dendritic cells once they are activated?
What happens to the expression of pattern recognition receptors (PRRs) in dendritic cells once they are activated?
- They become inactive
- They remain unchanged
- They are upregulated
- They are downregulated (correct)
Which DC type has very high levels of PRRs and is capable of producing a lot of type I interferon (IFN)?
Which DC type has very high levels of PRRs and is capable of producing a lot of type I interferon (IFN)?
How do T cells enter the lymph node?
How do T cells enter the lymph node?
What is the main role of tissue-resident macrophages with DC morphology when conventional DCs are absent?
What is the main role of tissue-resident macrophages with DC morphology when conventional DCs are absent?
What happens if a T cell does not encounter its specific antigen in the lymph node?
What happens if a T cell does not encounter its specific antigen in the lymph node?
Which blood vessels do T and B cells use to enter the lymph node?
Which blood vessels do T and B cells use to enter the lymph node?
What is the main function of effector T cells in the immune response?
What is the main function of effector T cells in the immune response?
If a transfer of antigens to resident dendritic cells occurs in the lymph node, what may be the reason for this?
If a transfer of antigens to resident dendritic cells occurs in the lymph node, what may be the reason for this?
