6 Questions
Which type of cell is responsible for cross-presentation of antigens?
Dendritic cells
Once CD8+ T cells have differentiated into CTLs, how do they kill infected host cells or tumor cells?
By recognizing antigens
What is the role of cross-presentation in organ transplants?
It initiates CD8+ T cell responses
Which cells are responsible for presenting ingested antigens on class I MHC molecules to CD8+ T lymphocytes?
Dendritic cells
Where do naive CD8+ T lymphocytes respond to intracellular antigens of infected cells?
Lymph nodes
How do dendritic cells present diverse tumor antigens to naive CD8+ T cells in lymph nodes?
By transporting ingested antigens into the cytosol
Test your knowledge on dendritic cells and antigen presentation pathways with this quiz. Learn about the unique ability of some dendritic cells to present ingested antigens on class I MHC molecules to CD8+ T lymphocytes, contrary to the general rule for APCs. Explore the initial response of naive CD8+ T cells and their requirement for antigen presentation by mature dendritic cells.
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