16 Questions
Which condition is characterized by stable increased intracranial pressure (ICP)?
Normal pressure hydrocephalus
Which disease is a prion disease associated with dementia?
Creuzfeldt-Jacob disease (CJD)
Which protein is the predominant component of amyloid plaques in Alzheimer's Disease?
Amyloid-β peptide
What is the primary component of neurofibrillary tangles in Alzheimer's Disease?
Tau protein
Which of the following is NOT associated with the institutionalization phase of Alzheimer's Disease?
Dysgeusia/dysosmia
What is the approximate percentage of Alzheimer's Disease cases that may also exhibit overt parkinsonism?
20%
Which part of the brain is NOT commonly affected by cerebral atrophy and ventricular enlargement in Alzheimer's Disease?
Occipital lobe
Which neurotransmitter shows a deficit in central cholinergic transmission in Alzheimer's Disease?
Acetylcholine
Which neurotransmitter shows a decrease in synthesis due to the loss of cells in the locus coeruleus in Alzheimer's Disease?
Norepinephrine
Which treatment for Alzheimer's Disease is known to have considerable side effects?
Cholinergic drugs
Which one of the following cannot be a common side effect of NMDA antagonist memantine?
Insomnia
What disrupts the activity of γ-Secretase in Alzheimer’s Disease?
NSAIDs
Which strategy for disrupting or preventing the formation of amyloid plaques is mentioned as hard to develop?
β-secretase (BASE) inhibitors
What is the main outcome of immunization with β-amyloid mentioned in the text?
Reduces plaque formation
Which of the following is a feature of nootropics (cognitive enhancers) as mentioned in the text?
Ability to enhance memory and learning
What does the clinical failure of tau aggregate inhibitors and NT modulators support, as per the text?
The viewpoint that the disease becomes independent of Aβ production at some point
Test your knowledge of aging and brain function with this quiz on dementia. Explore the causes, symptoms, and treatment options for this progressive decline in mental function, including Alzheimer's disease, stroke, and Parkinson's disease.
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