Cytokines Quiz

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Questions and Answers

Which type of action of cytokines affects multiple cell types?

  • Synergy
  • Antagonism
  • Redundancy
  • Pleiotropy (correct)

What type of cytokine action involves competing actions?

  • Synergy
  • Antagonism (correct)
  • Redundancy
  • Pleiotropy

Which cells are responsible for cytokine generation in adaptive immunity?

  • Fibroblasts
  • Endothelial cells
  • T lymphocytes (correct)
  • Macrophages

What is the characteristic of cytokines/hormones compared to growth factors?

<p>Short-lived stimuli and secretions (A)</p> Signup and view all the answers

How are cytokines classified based on structural studies?

<p>Molecular mass less than... (D)</p> Signup and view all the answers

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Study Notes

Cytokine Action

  • Pleiotropy is a type of cytokine action that affects multiple cell types.
  • Antagonism is where cytokines have opposing actions on the same cell.
  • Redundancy occurs when multiple cytokines have similar effects on the same cell.

Cytokine Generation in Adaptive Immunity

  • T lymphocytes (T cells) are the primary cell type responsible for cytokine generation in adaptive immunity.
  • Macrophages are another source of cytokines.

Cytokine Characteristics

  • Cytokines and hormones are characterized by acting at low concentrations.
  • Growth Factors act in high concentrations.

Cytokine Classification

  • Cytokines can be classified based on their structural similarity.
  • Four families of cytokines have been identified.
    • The hematopoietin family contains cytokines with similar alpha-helical structures.
    • The interferon family is composed of cytokines with similar structures.
    • The chemokine family comprises cytokines with similar structures.
    • The tumor necrosis factor family includes cytokines that have trimeric structures.

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