Cytokines in Acute Inflammation

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Questions and Answers

What is the usual outcome when the injury is limited or short-lived?

  • Extensive destruction of the tissue
  • Chronic inflammation
  • Healing by connective tissue replacement
  • Resolution (correct)

What happens when there is substantial tissue destruction?

  • Resolution occurs
  • Chronic inflammation develops
  • Healing by connective tissue replacement (correct)
  • Tissue regeneration is rapid

What is the result of the persistence of the injurious agent or some interferences in the normal healing process?

  • Healing by connective tissue replacement
  • Acute to chronic transition (correct)
  • Resolution
  • Tissue regeneration

What happens when the inflammatory injury involves tissues that are incapable of regeneration?

<p>Healing by connective tissue replacement (A)</p> Signup and view all the answers

What is the primary advantage of performing an autopsy of Virchow?

<p>Demonstrating pathologic change in the individual organs (B)</p> Signup and view all the answers

What is the process of removing the exudate with the restoration of normal tissue architecture?

<p>Resolution (B)</p> Signup and view all the answers

What can occur when there is abundant fibrin exudation in the tissue or even in serous cavities?

<p>Healing by connective tissue replacement (C)</p> Signup and view all the answers

What type of incision is commonly used for an aesthetic finish?

<p>T-Shaped Incision (C)</p> Signup and view all the answers

What is the main disadvantage of performing an autopsy of Virchow?

<p>It destroys the anatomic relationships of the organs (B)</p> Signup and view all the answers

In what type of cases is the T-Shaped Incision essential?

<p>Strangulation cases (A)</p> Signup and view all the answers

What is the advantage of performing an autopsy of Letulle?

<p>It is fast and easy (B)</p> Signup and view all the answers

What type of incision is commonly used for children?

<p>Single Vertical Cut (C)</p> Signup and view all the answers

What role do TNF and IL-1 play in acute inflammation?

<p>Promoting the adhesion of leukocytes to the endothelium and their migration (A)</p> Signup and view all the answers

What is the primary function of chemokines in acute inflammation?

<p>Serving as chemoattractants for specific types of leukocytes (D)</p> Signup and view all the answers

What is the result of the activation of complement proteins?

<p>Generation of breakdown products responsible for leukocyte chemotaxis (A)</p> Signup and view all the answers

What is the characteristic of chronic inflammation?

<p>Response of prolonged duration (weeks or months) (B)</p> Signup and view all the answers

Which of the following is a cause of chronic inflammation?

<p>Persistent infections that are difficult to eradicate (B)</p> Signup and view all the answers

What type of cells are primarily responsible for secreting chemokines?

<p>Lymphocytes, macrophages, and dendritic cells (D)</p> Signup and view all the answers

What is the main reason for the accumulation of leukocytes and the liberation of enzymes from those cells?

<p>Microbes stimulating cell activity (B)</p> Signup and view all the answers

What is the characteristic appearance of Caseous Necrosis?

<p>Creamy-yellow appearance (B)</p> Signup and view all the answers

What type of necrosis is typically caused by arterial occlusion?

<p>Coagulative necrosis (A)</p> Signup and view all the answers

What is the result of the conversion of destroyed cells in Caseous Necrosis?

<p>A granular, friable mass (A)</p> Signup and view all the answers

What is the term used to describe the massive death of tissue caused by a combination of ischemia and superimposed bacterial infection?

<p>Gangrenous necrosis (B)</p> Signup and view all the answers

In which location is gangrenous necrosis most often encountered?

<p>Lower extremities (B)</p> Signup and view all the answers

What is a common characteristic among genetic derangements that can cause cell injury?

<p>Abnormal protein function (B)</p> Signup and view all the answers

Which of the following is an example of an infectious agent that can cause cell injury?

<p>Virus (A)</p> Signup and view all the answers

What is the result of genetic defects that can trigger cell death?

<p>Formation of misfolded proteins (C)</p> Signup and view all the answers

Which of the following is an example of an environmental pollutant that can cause cell injury?

<p>Carbon monoxide (C)</p> Signup and view all the answers

What is the term for the immune reactions that cause cell injury?

<p>Immunologic reactions (C)</p> Signup and view all the answers

What is the result of nutritional imbalances that can cause cell injury?

<p>Deficiency in protein function (A)</p> Signup and view all the answers

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