Cytokines in Acute Inflammation
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Questions and Answers

What is the usual outcome when the injury is limited or short-lived?

  • Extensive destruction of the tissue
  • Chronic inflammation
  • Healing by connective tissue replacement
  • Resolution (correct)
  • What happens when there is substantial tissue destruction?

  • Resolution occurs
  • Chronic inflammation develops
  • Healing by connective tissue replacement (correct)
  • Tissue regeneration is rapid
  • What is the result of the persistence of the injurious agent or some interferences in the normal healing process?

  • Healing by connective tissue replacement
  • Acute to chronic transition (correct)
  • Resolution
  • Tissue regeneration
  • What happens when the inflammatory injury involves tissues that are incapable of regeneration?

    <p>Healing by connective tissue replacement</p> Signup and view all the answers

    What is the primary advantage of performing an autopsy of Virchow?

    <p>Demonstrating pathologic change in the individual organs</p> Signup and view all the answers

    What is the process of removing the exudate with the restoration of normal tissue architecture?

    <p>Resolution</p> Signup and view all the answers

    What can occur when there is abundant fibrin exudation in the tissue or even in serous cavities?

    <p>Healing by connective tissue replacement</p> Signup and view all the answers

    What type of incision is commonly used for an aesthetic finish?

    <p>T-Shaped Incision</p> Signup and view all the answers

    What is the main disadvantage of performing an autopsy of Virchow?

    <p>It destroys the anatomic relationships of the organs</p> Signup and view all the answers

    In what type of cases is the T-Shaped Incision essential?

    <p>Strangulation cases</p> Signup and view all the answers

    What is the advantage of performing an autopsy of Letulle?

    <p>It is fast and easy</p> Signup and view all the answers

    What type of incision is commonly used for children?

    <p>Single Vertical Cut</p> Signup and view all the answers

    What role do TNF and IL-1 play in acute inflammation?

    <p>Promoting the adhesion of leukocytes to the endothelium and their migration</p> Signup and view all the answers

    What is the primary function of chemokines in acute inflammation?

    <p>Serving as chemoattractants for specific types of leukocytes</p> Signup and view all the answers

    What is the result of the activation of complement proteins?

    <p>Generation of breakdown products responsible for leukocyte chemotaxis</p> Signup and view all the answers

    What is the characteristic of chronic inflammation?

    <p>Response of prolonged duration (weeks or months)</p> Signup and view all the answers

    Which of the following is a cause of chronic inflammation?

    <p>Persistent infections that are difficult to eradicate</p> Signup and view all the answers

    What type of cells are primarily responsible for secreting chemokines?

    <p>Lymphocytes, macrophages, and dendritic cells</p> Signup and view all the answers

    What is the main reason for the accumulation of leukocytes and the liberation of enzymes from those cells?

    <p>Microbes stimulating cell activity</p> Signup and view all the answers

    What is the characteristic appearance of Caseous Necrosis?

    <p>Creamy-yellow appearance</p> Signup and view all the answers

    What type of necrosis is typically caused by arterial occlusion?

    <p>Coagulative necrosis</p> Signup and view all the answers

    What is the result of the conversion of destroyed cells in Caseous Necrosis?

    <p>A granular, friable mass</p> Signup and view all the answers

    What is the term used to describe the massive death of tissue caused by a combination of ischemia and superimposed bacterial infection?

    <p>Gangrenous necrosis</p> Signup and view all the answers

    In which location is gangrenous necrosis most often encountered?

    <p>Lower extremities</p> Signup and view all the answers

    What is a common characteristic among genetic derangements that can cause cell injury?

    <p>Abnormal protein function</p> Signup and view all the answers

    Which of the following is an example of an infectious agent that can cause cell injury?

    <p>Virus</p> Signup and view all the answers

    What is the result of genetic defects that can trigger cell death?

    <p>Formation of misfolded proteins</p> Signup and view all the answers

    Which of the following is an example of an environmental pollutant that can cause cell injury?

    <p>Carbon monoxide</p> Signup and view all the answers

    What is the term for the immune reactions that cause cell injury?

    <p>Immunologic reactions</p> Signup and view all the answers

    What is the result of nutritional imbalances that can cause cell injury?

    <p>Deficiency in protein function</p> Signup and view all the answers

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