21 Questions
Which of the following is a characteristic of Cushing syndrome?
Decreased bone density
What is a common cause of Cushing syndrome?
Long-term treatment with glucocorticoids
What is a test for Cushing syndrome?
Evaluation of muscle strength
Which hormone is primarily responsible for causing spontaneous Cushing syndrome?
Adrenocorticotropic hormone (ACTH)
What is the main cause of nonendocrine ectopic ACTH production in spontaneous Cushing syndrome?
All of the above
What percentage of spontaneous Cushing syndrome cases are caused by an ACTH-independent process?
10% to 20%
What is the recommended dose of hydrocortisone for patients undergoing unilateral adrenal resection?
100 mg every 24 hours
Which of the following is a characteristic of Cushing syndrome?
Decreased formation of bone matrix
What is a common cause of Cushing syndrome?
Long-term treatment with glucocorticoids
What is a test for Cushing syndrome?
Asking the patient to get up from a chair without using the hands
What is the most common cause of spontaneous Cushing syndrome?
Pituitary microadenoma
What is the recommended treatment for marked hypokalemic alkalosis caused by ectopic ACTH production?
Spironolactone
What is the perioperative morbidity rate associated with bilateral adrenalectomy in patients with Cushing syndrome?
Up to 20%
What is the goal of glucocorticoid replacement therapy in patients given adrenal suppressants?
Complete adrenal suppression
Which of the following is a characteristic of Cushing syndrome?
Centripetal distribution of fat
What is a common symptom of glucocorticoid excess (Cushing syndrome)?
Easy bruising
What is the most common cause of Cushing syndrome?
Administration of glucocorticoids
Which hormone is responsible for causing 65% to 75% of all spontaneous cases of Cushing syndrome?
ACTH
What is the common cause of marked hypokalemic alkalosis in patients with Cushing syndrome?
Aldosterone antagonist spironolactone
What is the recommended dose of hydrocortisone for patients undergoing bilateral adrenal resection?
100 mg every 24 hours intravenously
What is the incidence of pneumothorax in an open adrenal resection approach?
20%
Test your knowledge on the symptoms and effects of glucocorticoid excess, also known as Cushing syndrome. Learn about the moon-faced appearance, fat distribution, thin skin, and other characteristic features of this condition.
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