32, Adrenocortical Hormone Excess
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Questions and Answers

Which of the following is a characteristic of Cushing syndrome?

  • Hypotension
  • Decreased bone density (correct)
  • Increased muscle mass
  • Peripheral edema
  • What is a common cause of Cushing syndrome?

  • Long-term treatment with glucocorticoids (correct)
  • Endogenous oversecretion of glucocorticoids
  • Low renin substrate levels
  • Impaired absorption of calcium
  • What is a test for Cushing syndrome?

  • Blood test for renin levels
  • Evaluation of muscle strength (correct)
  • Measurement of peripheral edema
  • Assessment of bone density
  • Which hormone is primarily responsible for causing spontaneous Cushing syndrome?

    <p>Adrenocorticotropic hormone (ACTH)</p> Signup and view all the answers

    What is the main cause of nonendocrine ectopic ACTH production in spontaneous Cushing syndrome?

    <p>All of the above</p> Signup and view all the answers

    What percentage of spontaneous Cushing syndrome cases are caused by an ACTH-independent process?

    <p>10% to 20%</p> Signup and view all the answers

    What is the recommended dose of hydrocortisone for patients undergoing unilateral adrenal resection?

    <p>100 mg every 24 hours</p> Signup and view all the answers

    Which of the following is a characteristic of Cushing syndrome?

    <p>Decreased formation of bone matrix</p> Signup and view all the answers

    What is a common cause of Cushing syndrome?

    <p>Long-term treatment with glucocorticoids</p> Signup and view all the answers

    What is a test for Cushing syndrome?

    <p>Asking the patient to get up from a chair without using the hands</p> Signup and view all the answers

    What is the most common cause of spontaneous Cushing syndrome?

    <p>Pituitary microadenoma</p> Signup and view all the answers

    What is the recommended treatment for marked hypokalemic alkalosis caused by ectopic ACTH production?

    <p>Spironolactone</p> Signup and view all the answers

    What is the perioperative morbidity rate associated with bilateral adrenalectomy in patients with Cushing syndrome?

    <p>Up to 20%</p> Signup and view all the answers

    What is the goal of glucocorticoid replacement therapy in patients given adrenal suppressants?

    <p>Complete adrenal suppression</p> Signup and view all the answers

    Which of the following is a characteristic of Cushing syndrome?

    <p>Centripetal distribution of fat</p> Signup and view all the answers

    What is a common symptom of glucocorticoid excess (Cushing syndrome)?

    <p>Easy bruising</p> Signup and view all the answers

    What is the most common cause of Cushing syndrome?

    <p>Administration of glucocorticoids</p> Signup and view all the answers

    Which hormone is responsible for causing 65% to 75% of all spontaneous cases of Cushing syndrome?

    <p>ACTH</p> Signup and view all the answers

    What is the common cause of marked hypokalemic alkalosis in patients with Cushing syndrome?

    <p>Aldosterone antagonist spironolactone</p> Signup and view all the answers

    What is the recommended dose of hydrocortisone for patients undergoing bilateral adrenal resection?

    <p>100 mg every 24 hours intravenously</p> Signup and view all the answers

    What is the incidence of pneumothorax in an open adrenal resection approach?

    <p>20%</p> Signup and view all the answers

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