32. Adrenocortical Hormone Deficiency
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Questions and Answers

Which is the most common cause of primary (nonexogenous) bilateral ACTH deficiency in the United States?

  • Autoimmune disease (correct)
  • Tuberculosis
  • Cytotoxic drugs
  • Congenital adrenal hyperplasia
  • Which condition is associated with local destruction of all zones of the adrenal cortex?

  • Cytotoxic drugs
  • Congenital adrenal hyperplasia
  • Addison disease (correct)
  • Sheehan syndrome
  • Which condition is NOT a cause of adrenocortical insufficiency?

  • Autoimmune disease
  • HIV (correct)
  • Cytotoxic drugs
  • Tuberculosis
  • Which condition is characterized by enzymatic defects in cortisol synthesis, compensatory elevations in ACTH, and congenital adrenal hyperplasia?

    <p>Primary adrenal insufficiency</p> Signup and view all the answers

    What can happen when even a minor stress is present in glucocorticoid-deficient patients?

    <p>Acute adrenal crisis</p> Signup and view all the answers

    What is the recommended perioperative glucocorticoid regimen for patients with adrenal insufficiency?

    <p>The patient's usual daily dose plus 50 to 100 mg of hydrocortisone before surgical incision</p> Signup and view all the answers

    Which is the leading cause of underproduction of corticosteroids?

    <p>Withdrawal of steroids</p> Signup and view all the answers

    What is the most common cause of primary (nonexogenous) bilateral ACTH deficiency in the United States?

    <p>Autoimmune disease</p> Signup and view all the answers

    Which condition is associated with both glucocorticoid and mineralocorticoid deficiency if the insufficiency is bilateral?

    <p>Addison disease</p> Signup and view all the answers

    Which condition is characterized by compensatory elevations in ACTH and congenital adrenal hyperplasia?

    <p>Adrenal insufficiency</p> Signup and view all the answers

    What is the most common cause of secondary adrenal insufficiency?

    <p>Pituitary or hypothalamic tumor</p> Signup and view all the answers

    What is the recommended perioperative glucocorticoid regimen for patients with adrenal insufficiency?

    <p>25 mg hydrocortisone phosphate intravenously at the start of the operative procedure</p> Signup and view all the answers

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