32. Physiologic Properties of Adrenocortical Hormones

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Questions and Answers

Which hormones from the adrenal cortex are major sources of androgen in women?

  • Cortisol and corticosterone
  • Testosterone and dihydrotestosterone
  • Androstenedione and dehydroepiandrosterone (correct)
  • Estrogen and progesterone

Excess secretion of androgen can result in which of the following conditions?

  • Osteoporosis
  • Hyperthyroidism
  • Masculinization (correct)
  • Hypogonadism

What is the principal glucocorticoid that regulates carbohydrate, protein, lipid, and nucleic acid metabolism?

  • Estrogen
  • Progesterone
  • Testosterone
  • Cortisol (correct)

Which form of cortisol is the most accurate measure of cortisol activity?

<p>Unbound cortisol (A)</p> Signup and view all the answers

What is the serum half-life of cortisol?

<p>80 to 110 minutes (D)</p> Signup and view all the answers

Why are pharmacokinetic data based on serum levels not good indicators of cortisol activity?

<p>Cortisol acts through intracellular receptors (D)</p> Signup and view all the answers

How are treatment schedules for glucocorticoid replacement therapy determined?

<p>Based on the prolonged end-organ effect of glucocorticoids (A)</p> Signup and view all the answers

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