32. Physiologic Properties of Adrenocortical Hormones
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Questions and Answers

Which hormones from the adrenal cortex are major sources of androgen in women?

  • Cortisol and corticosterone
  • Testosterone and dihydrotestosterone
  • Androstenedione and dehydroepiandrosterone (correct)
  • Estrogen and progesterone
  • Excess secretion of androgen can result in which of the following conditions?

  • Osteoporosis
  • Hyperthyroidism
  • Masculinization (correct)
  • Hypogonadism
  • What is the principal glucocorticoid that regulates carbohydrate, protein, lipid, and nucleic acid metabolism?

  • Estrogen
  • Progesterone
  • Testosterone
  • Cortisol (correct)
  • Which form of cortisol is the most accurate measure of cortisol activity?

    <p>Unbound cortisol</p> Signup and view all the answers

    What is the serum half-life of cortisol?

    <p>80 to 110 minutes</p> Signup and view all the answers

    Why are pharmacokinetic data based on serum levels not good indicators of cortisol activity?

    <p>Cortisol acts through intracellular receptors</p> Signup and view all the answers

    How are treatment schedules for glucocorticoid replacement therapy determined?

    <p>Based on the prolonged end-organ effect of glucocorticoids</p> Signup and view all the answers

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