7 Questions
Which hormones from the adrenal cortex are major sources of androgen in women?
Androstenedione and dehydroepiandrosterone
Excess secretion of androgen can result in which of the following conditions?
Masculinization
What is the principal glucocorticoid that regulates carbohydrate, protein, lipid, and nucleic acid metabolism?
Cortisol
Which form of cortisol is the most accurate measure of cortisol activity?
Unbound cortisol
What is the serum half-life of cortisol?
80 to 110 minutes
Why are pharmacokinetic data based on serum levels not good indicators of cortisol activity?
Cortisol acts through intracellular receptors
How are treatment schedules for glucocorticoid replacement therapy determined?
Based on the prolonged end-organ effect of glucocorticoids
Test your knowledge on the physiologic properties of adrenocortical hormones, specifically focusing on androgens such as androstenedione and dehydroepiandrosterone. Learn about their role as major sources of androgens in women and the potential consequences of excess secretion. Explore how these hormones can cause masculinization, pseudopuberty, or female pseudohermaphroditism.
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