Cumulative Incidence in Health Sciences

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Questions and Answers

What is the main difference between measuring presence and measuring occurrence of health indicators?

  • Presence measurement is based on prevalence and odds, while occurrence measurement is based on cumulative incidence and incidence rate.
  • Presence measurement is useful for acute health indicators, while occurrence measurement is useful for chronic health indicators.
  • Presence measurement is related to new cases, while occurrence measurement is related to the evolution of the health indicator over time.
  • Presence measurement is useful for time-dependent outcomes, while occurrence measurement is useful for unchanging characteristics. (correct)

Which type of health indicator is best measured using prevalence and odds?

  • Time-dependent outcomes
  • Unchanging characteristics
  • Chronic health indicators (correct)
  • Acute health indicators

What does cumulative incidence measure?

  • The evolution of a health indicator over time
  • The prevalence and odds of a chronic health indicator
  • The presence of a health indicator among individuals
  • The occurrence of new cases related to a health indicator over time (correct)

When is measuring occurrence particularly useful?

<p>For time-dependent outcomes (C)</p> Signup and view all the answers

What is the difference between cumulative incidence and incidence rate?

<p>Cumulative incidence measures new cases over a specific period, while incidence rate measures the evolution of a health indicator over time. (C)</p> Signup and view all the answers

Which measurement is particularly useful for assessing unchanging characteristics like asthma or diabetes?

<p>Measuring prevalence (C)</p> Signup and view all the answers

What does the p-value of 0.548 indicate?

<p>No evidence against the null hypothesis (D)</p> Signup and view all the answers

In epidemiology, what is the incidence rate?

<p>The number of new cases per person-time at risk unit (D)</p> Signup and view all the answers

What is the main difference between cumulative incidence (CI) and incidence rate (Ir)?

<p>CI depends on the total time at risk, while Ir depends on the proportion of new cases in the cohort (D)</p> Signup and view all the answers

How can a confidence interval for the incidence rate (Ir) be obtained?

<p>Based on a Poisson distribution or an approximation based on the normal distribution (D)</p> Signup and view all the answers

What distribution is assumed for the time to the beginning of the illness when estimating cumulative incidence?

<p>Exponential distribution (C)</p> Signup and view all the answers

What does the Wald test in epidemiology compare for two incidence rates?

<p>The expectation and variance of new cases in each population area (C)</p> Signup and view all the answers

What value is compared to a chi-squared distribution in the Wald test for comparing two incidence rates?

<p>(I1 ∆t0 - I0 ∆t1)2 / Var(Ij) (D)</p> Signup and view all the answers

What does the p-value indicate in the context of the Wald test for comparing two incidence rates?

<p>The probability that there is no difference in the number of new cases between the two populations (A)</p> Signup and view all the answers

What does it mean if Ir could be time varying in epidemiological terms?

<p>The probability of getting the disease changes over time (A)</p> Signup and view all the answers

How is cumulative incidence (CI) estimated in epidemiology?

<p>By using the proportion of new cases in the cohort (B)</p> Signup and view all the answers

What is required to estimate incidence rate (Ir) in epidemiological studies?

<p>Having information on both the number of new cases and total time at risk for each individual in the study (B)</p> Signup and view all the answers

In epidemiology, what does Ir represent?

<p>The expansion speed of a disease in a population at a particular time point (D)</p> Signup and view all the answers

What is the prevalence (P) of a given disease D within a given time interval of length $t$?

<p>The proportion of individuals affected by D in the population of interest (A)</p> Signup and view all the answers

What is the main limitation of the approximated confidence interval formula (1)?

<p>It may give an upper bound of the confidence interval higher than 1 or a lower bound lower than 0 (B)</p> Signup and view all the answers

In which type of studies is it not possible to estimate prevalence?

<p>A and B (D)</p> Signup and view all the answers

What statistical tests can be used to compare prevalence in two different populations?

<p>binom.test and prop.test (C)</p> Signup and view all the answers

Which measure is particularly useful for assessing unchanging characteristics like asthma or diabetes?

<p>Prevalence (A)</p> Signup and view all the answers

What is the main difference between measuring presence and measuring occurrence of health indicators?

<p>Presence refers to the existence of a health indicator, while occurrence refers to the frequency of its appearance (C)</p> Signup and view all the answers

$CI = \frac{I}{N0}$, where $I$ is the number of new cases and $N0$ is the disease-free population size. What does $I$ represent in this formula?

<p>$I$ represents the total number of new cases within a given time interval (B)</p> Signup and view all the answers

Which measure is sensitive to the duration of the disease in an individual?

<p>Prevalence (C)</p> Signup and view all the answers

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