Biostats Module 3

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Questions and Answers

What does a correlation coefficient of -1.00 indicate?

  • Moderate positive correlation
  • No correlation
  • Perfect negative correlation (correct)
  • Perfect positive correlation

Which test does not rely on the normality assumption?

  • Spearman Rank Correlation
  • Pearson Correlation Coefficient
  • Simple Linear Regression
  • Nonparametric tests (correct)

What does the Spearman Rank Correlation assess?

  • Direction of relationship
  • Strength and direction of a relationship
  • Normality of data
  • Independence of variables (correct)

In regression, what is the coefficient of determination (r^2) used for?

<p>Explaining the percentage of variance explained by the independent variable (D)</p>
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What is a core assumption for Simple Linear Regression?

<p>Homogeneity of variances (D)</p>
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When two variables move in opposite directions, this is known as:

<p>Perfect negative correlation (B)</p>
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Which statement about nonparametric tests is true?

<p>They are less powerful than parametric tests (B)</p>
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What type of data is suitable for the Mann-Whitney U test?

<p>Ordinal (A)</p>
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In what situation would you use the Wilcoxon Signed-Rank Test?

<p>Evaluating ranks for paired measurements (B)</p>
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When conducting the Kruskal-Wallis test, how many groups are being compared?

<p>3 groups (A)</p>
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What is a key assumption for the Chi-Square test?

<p>Independent and categorical data (D)</p>
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Under what condition should Fisher's Exact test be used?

<p>When more than 20% of cells have expected counts less than 5 in the Chi-Square test (D)</p>
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Which test is suitable for comparing medians between two independent groups?

<p>Mann-Whitney U test (D)</p>
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What assumption is common between the Kruskal-Wallis and Mann-Whitney U tests?

<p>Random samples (C)</p>
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Which correlation coefficient indicates the weakest relationship between two variables?

<p>0.25 (A)</p>
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What is the primary difference between Pearson and Spearman correlation coefficients?

<p>Pearson requires normality and interval/ratio data, while Spearman does not. (B)</p>
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Which of the following indicates the percentage of variance in the dependent variable that can be explained by the independent variable?

<p>Coefficient of determination (r^2) (A)</p>
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What is a disadvantage of nonparametric tests compared to parametric tests?

<p>Nonparametric tests are less powerful. (D)</p>
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Which of the following best describes the difference between correlation and regression?

<p>Correlation examines the relationship between variables, while regression uses the relationship for prediction. (C)</p>
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Under which condition would simple linear regression be appropriate for analyzing a dataset?

<p>When variables are interval/ratio level data, independent, and linearly correlated. (A)</p>
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Which of the following is an assumption of both Pearson and Spearman correlation coefficients?

<p>Independence (A)</p>
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What is a key difference between the Mann-Whitney U test and the Wilcoxon Signed-Rank Test?

<p>The Wilcoxon Signed-Rank Test evaluates ranks for differences in measurements while the Mann-Whitney U test evaluates medians. (A)</p>
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What distinguishes Kruskal-Wallis test from Mann-Whitney U test?

<p>Mann-Whitney U test evaluates differences between two groups while Kruskal-Wallis test compares three or more groups. (C)</p>
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Which assumption is unique to the Chi-Square test compared to other nonparametric tests?

<p>Chi-Square needs expected counts to be greater than 1 and no more than 20% of cells less than 5. (D)</p>
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When would you use Fisher's Exact test instead of the Chi-Square test?

<p>When expected counts are not met for Chi-Square assumptions. (D)</p>
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What distinguishes the Wilcoxon Signed-Rank Test from the Mann-Whitney U test in terms of data requirements?

<p>Wilcoxon Signed-Rank Test requires ordinal/interval/ratio data while Mann-Whitney U does not have this requirement. (C)</p>
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What assumption differentiates the Kruskal-Wallis test from the Chi-Square test?

<p>Kruskal-Wallis requires ordinal/interval/ratio level data, unlike Chi-Square. (A)</p>
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What makes Fisher's Exact test unique compared to other nonparametric tests?

<p>Fisher's Exact test can be used with very small sample sizes where Chi-Square assumptions are violated. (A)</p>
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What distinguishes the Wilcoxon Signed-Rank Test from the Kruskal-Wallis test in terms of their application?

<p>Wilcoxon Signed-Rank Test compares ranks within a group, while Kruskal-Wallis compares ranks between groups. (C)</p>
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Study Notes

Correlation

  • Evaluates the relationship between variables and direction of relationship
  • Positively related: both move in the same direction
  • Negatively related: move in opposite directions
  • Correlation does not equal causation
  • Correlation Coefficient: describes the strength and direction of a relationship, ranges from -1.00 to +1.00
  • -1.00 = perfect negative correlation
  • +1.00 = perfect positive correlation

Pearson Correlation Coefficient

  • Assumptions: independence, normality, variables are interval/ratio level data

Spearman Rank Correlation

  • Assumptions: independence

Regression

  • Uses the relationship between variables as a basis for prediction
  • Takes correlation a step further
  • Simple Linear Regression: examines two variables that are linearly correlated
  • Simple Linear Regression assumptions: normality, homogeneity of variances (Levene's test), and dependent variable is interval/ratio level data
  • Regression Line formula: Y = a + bX
  • Y = dependent variable
  • a and b = constants
  • X = independent variable
  • r = correlation coefficient
  • r2 = coefficient of determination (percentage of the variance in the dependent variable that can be explained by the independent variable)

Nonparametric Tests

  • Do not rely on probability distribution (normality assumption)
  • Do not have homogeneity of variances
  • Can be used to examine nominal or ordinal level data
  • Less powerful than parametric tests

Mann-Whitney U Test

  • Evaluates whether medians differ significantly between two groups
  • Assumptions: random samples, independence, and dependent variable is ordinal/interval/ratio level

Wilcoxon Signed-Rank Test

  • Evaluates ranks for the difference between the measurements (use a before and after score and subtract to find rank)
  • Cannot be used with ordinal data
  • Assumptions: random samples and dependent variable is interval/ratio level

Kruskal-Wallis Test

  • Evaluates whether medians differ significantly between 3+ groups
  • Assumptions: random samples, independence, and dependent variable is ordinal/interval/ratio level data

Chi-Square Test

  • Evaluates expected frequencies and observed frequencies of categorical (ordinal and nominal) data
  • Assumptions: independence, expected counts are greater than 1 and no more than 20% of cells are less than 5

Fisher's Exact Test

  • Used if Chi-Square assumptions are not met

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