Questions and Answers
What is the optimum temperature range for the growth of coronavirus in the upper respiratory tract?
33-35°C
What is the result of the replication of coronavirus?
Generation of individual mRNA's for individual viral proteins
What is the characteristic appearance of glycoproteins on the outer layer of coronavirus?
Club-shaped projections
What is the name of the respiratory tract disorder caused by a type of coronavirus?
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Where does the replication of coronavirus take place?
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Study Notes
Coronavirus Structure and Replication
- The coronavirus has a crown-like shape, with glycoproteins on the outer layer appearing as club-shaped projections, giving a halo-like appearance on electron microscopy.
- The virus is encapsulated, with a king-like structure wearing a robe, representing the nucleus surrounded by a protective layer.
Replication and Evolution
- Replication of coronavirus generates individual mRNA's for individual viral proteins, increasing the capacity for genetic drift (evolution/resistance).
- The virus replicates in the cytoplasm, with the king (nucleus) outside the castle (cytoplasm).
Infection and Transmission
- Sneezing and blowing one's nose can cause the common cold.
- Coronavirus infections are usually limited to the upper respiratory tract because the optimum temperature for growth is between 33°C and 35°C.
SARS and Respiratory Tract
- SARS is a type of coronavirus that infects the lower respiratory tract and causes acute respiratory distress.
- The king's respiratory tract design is associated with SARS and Middle East Respiratory Syndrome (MERS), as well as acute bronchitis.
- X-ray shows spontaneous pneumothorax in SARS cases.
