Questions and Answers
What is the genome composition of the coronavirus?
Single-stranded RNA, linear, nonsegmented positive-sense
Which of the following proteins are NOT mentioned as being part of the coronavirus?
Lipopolysaccharides
Which illness is NOT directly attributed to coronaviruses according to the text?
Ebola virus disease
What are the characteristics of the coronavirus envelope?
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What is the primary structure of the coronavirus nucleocapsid?
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Study Notes
Corona Virus Characteristics
- Large, enveloped RNA virus
- Causes lower respiratory tract infections and implicated in gastrointestinal illness
Structure and Genome
- Virion: spherical, 120-150 nm in diameter, helical nucleocapsid
- Genome: single-stranded RNA, linear, non-segmented, positive-sense, 27-32 kb, capped and polyadenylated
Proteins
- Two glycoproteins
- Some viruses contain hundreds of nucleocapsid phosphoproteins
- Some viruses contain hemagglutinin esterase (a type of surface glycoprotein)
Envelope
- Contains large, widely spaced, club- or petal-shaped spikes
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