Podcast
Questions and Answers
What is the first action to take when a patient presents with suspected acute myocardial infarction?
What is the first action to take when a patient presents with suspected acute myocardial infarction?
- Start a beta-blocker
- Conduct a coronary angiography
- Provide high-flow oxygen (correct)
- Administer oral nitrates
Which enzyme is commonly used as a biochemical marker for diagnosing myocardial infarction?
Which enzyme is commonly used as a biochemical marker for diagnosing myocardial infarction?
- Alkaline phosphatase
- Creatine kinase-MB (CK-MB) (correct)
- Lactate dehydrogenase (LDH)
- Aspartate aminotransferase (AST)
What are the common symptoms of myocardial infarction apart from chest pain?
What are the common symptoms of myocardial infarction apart from chest pain?
- Persistent headache and vision changes
- High fever and chills
- Nausea and partial paralysis
- Breathlessness and syncope (correct)
What does the development of a Q wave in an ECG indicate during a myocardial infarction?
What does the development of a Q wave in an ECG indicate during a myocardial infarction?
Why are serial estimations of cardiac biomarkers important in diagnosing myocardial infarction?
Why are serial estimations of cardiac biomarkers important in diagnosing myocardial infarction?
Which of the following is NOT a characteristic symptom of myocardial infarction?
Which of the following is NOT a characteristic symptom of myocardial infarction?
What should be considered for patients at moderate or high risk of myocardial infarction?
What should be considered for patients at moderate or high risk of myocardial infarction?
If a beta-blocker is contraindicated in the management of myocardial infarction, what alternative medication may be considered?
If a beta-blocker is contraindicated in the management of myocardial infarction, what alternative medication may be considered?
What is the primary underlying cause of coronary heart disease?
What is the primary underlying cause of coronary heart disease?
Which of the following is defined as myocardial necrosis due to acute occlusion of a coronary artery?
Which of the following is defined as myocardial necrosis due to acute occlusion of a coronary artery?
What is the clinical manifestation associated with transient myocardial ischaemia?
What is the clinical manifestation associated with transient myocardial ischaemia?
Which factor can precipitate chronic stable angina?
Which factor can precipitate chronic stable angina?
What is a significant characteristic of unstable angina?
What is a significant characteristic of unstable angina?
Which of the following is NOT a risk factor commonly associated with coronary heart disease?
Which of the following is NOT a risk factor commonly associated with coronary heart disease?
Which of the following is NOT a component of the management of angina pectoris?
Which of the following is NOT a component of the management of angina pectoris?
What type of alterations are seen in the ECG changes during acute ST-elevation myocardial infarction?
What type of alterations are seen in the ECG changes during acute ST-elevation myocardial infarction?
What is the main type of myocardial dysfunction resulting from ischemia or infarction?
What is the main type of myocardial dysfunction resulting from ischemia or infarction?
What should patients with stable angina avoid for safety?
What should patients with stable angina avoid for safety?
Which class of drugs is used as anti-anginal treatment?
Which class of drugs is used as anti-anginal treatment?
What type of heart condition is characterized by rapid worsening angina or angina at rest?
What type of heart condition is characterized by rapid worsening angina or angina at rest?
Which medication type is used in both antiplatelet and anticoagulant therapy for acute chest pain management?
Which medication type is used in both antiplatelet and anticoagulant therapy for acute chest pain management?
What is the primary purpose of serial measurements of biochemical markers in chest pain assessment?
What is the primary purpose of serial measurements of biochemical markers in chest pain assessment?
Which of the following surgical options is used for the treatment of ischemic heart disease?
Which of the following surgical options is used for the treatment of ischemic heart disease?
What lifestyle change is recommended to manage stable angina effectively?
What lifestyle change is recommended to manage stable angina effectively?
Which medication is preferable for the initial management of stable angina?
Which medication is preferable for the initial management of stable angina?
What is a common complication associated with myocardial infarction?
What is a common complication associated with myocardial infarction?
Which of the following is NOT part of the management protocol for unstable angina?
Which of the following is NOT part of the management protocol for unstable angina?
Which of the following is a mechanical complication of myocardial infarction?
Which of the following is a mechanical complication of myocardial infarction?
What is the initial measure in the management of acute ST-elevation myocardial infarction?
What is the initial measure in the management of acute ST-elevation myocardial infarction?
Which investigation is useful in diagnosing stable angina?
Which investigation is useful in diagnosing stable angina?
What is the role of clopidogrel in the management of coronary heart disease?
What is the role of clopidogrel in the management of coronary heart disease?
Which of the following is a main characteristic of unstable angina?
Which of the following is a main characteristic of unstable angina?
Which of the following factors is considered an independent risk factor for coronary heart disease?
Which of the following factors is considered an independent risk factor for coronary heart disease?
What role does HDL cholesterol have in heart health?
What role does HDL cholesterol have in heart health?
What condition could potentially decrease oxygen supply to the myocardium?
What condition could potentially decrease oxygen supply to the myocardium?
How does obesity contribute to the development of coronary heart disease?
How does obesity contribute to the development of coronary heart disease?
Which of the following is NOT a common precipitating activity for stable angina?
Which of the following is NOT a common precipitating activity for stable angina?
What is the primary function of triglycerides in relation to heart disease?
What is the primary function of triglycerides in relation to heart disease?
Which of the following conditions increases myocardial oxygen demand?
Which of the following conditions increases myocardial oxygen demand?
What is a primary symptom of stable angina?
What is a primary symptom of stable angina?
Flashcards
Coronary Heart Disease (CHD)
Coronary Heart Disease (CHD)
The most common type of heart disease globally, often leading to premature death.
Angina Pectoris
Angina Pectoris
Chest pain caused by temporary lack of oxygen to the heart muscle.
Stable Angina
Stable Angina
A condition where angina occurs consistently under certain predictable conditions, like exertion.
Unstable Angina
Unstable Angina
Signup and view all the flashcards
Myocardial Infarction (MI)
Myocardial Infarction (MI)
Signup and view all the flashcards
Heart Failure
Heart Failure
Signup and view all the flashcards
Arrhythmia
Arrhythmia
Signup and view all the flashcards
Sudden Death
Sudden Death
Signup and view all the flashcards
LDL (Low-Density Lipoprotein)
LDL (Low-Density Lipoprotein)
Signup and view all the flashcards
HDL (High-Density Lipoprotein)
HDL (High-Density Lipoprotein)
Signup and view all the flashcards
Triglycerides
Triglycerides
Signup and view all the flashcards
Resting ECG
Resting ECG
Signup and view all the flashcards
Exercise ECG
Exercise ECG
Signup and view all the flashcards
Myocardial Perfusion Scanning
Myocardial Perfusion Scanning
Signup and view all the flashcards
Stress Echocardiography
Stress Echocardiography
Signup and view all the flashcards
Coronary Arteriography
Coronary Arteriography
Signup and view all the flashcards
Percutaneous Coronary Intervention (PCI)
Percutaneous Coronary Intervention (PCI)
Signup and view all the flashcards
Coronary Artery Bypass Graft (CABG)
Coronary Artery Bypass Graft (CABG)
Signup and view all the flashcards
Antiplatelet Therapy
Antiplatelet Therapy
Signup and view all the flashcards
Lipid-lowering Therapy
Lipid-lowering Therapy
Signup and view all the flashcards
Analgesia (opiates)
Analgesia (opiates)
Signup and view all the flashcards
Antiemetic
Antiemetic
Signup and view all the flashcards
Reperfusion
Reperfusion
Signup and view all the flashcards
Ischemia
Ischemia
Signup and view all the flashcards
Beta-blockers
Beta-blockers
Signup and view all the flashcards
Nitrates
Nitrates
Signup and view all the flashcards
What causes a myocardial infarction?
What causes a myocardial infarction?
Signup and view all the flashcards
What is the cardinal symptom of a myocardial infarction?
What is the cardinal symptom of a myocardial infarction?
Signup and view all the flashcards
Describe the typical ECG changes seen in a myocardial infarction.
Describe the typical ECG changes seen in a myocardial infarction.
Signup and view all the flashcards
What are some biochemical markers used to detect a myocardial infarction?
What are some biochemical markers used to detect a myocardial infarction?
Signup and view all the flashcards
What is the immediate management of a patient with suspected acute myocardial infarction?
What is the immediate management of a patient with suspected acute myocardial infarction?
Signup and view all the flashcards
Where are patients with acute myocardial infarction typically managed?
Where are patients with acute myocardial infarction typically managed?
Signup and view all the flashcards
What medication options are available for the immediate treatment of acute myocardial infarction?
What medication options are available for the immediate treatment of acute myocardial infarction?
Signup and view all the flashcards
What procedures may be performed for patients with acute myocardial infarction?
What procedures may be performed for patients with acute myocardial infarction?
Signup and view all the flashcards
Study Notes
Coronary Heart Disease (CHD)
- CHD is the most common form of heart disease and a leading cause of premature death in certain parts of the world.
- It's almost always due to atheroma and its complications, particularly thrombosis in the coronary arteries.
- CHD can manifest in various ways, including stable angina, unstable angina, myocardial infarction, heart failure, arrhythmias, and sudden death.
Stable Angina
- Ischemia (reduced blood flow) due to fixed atheromatous stenosis (narrowing of the arteries) in one or more coronary arteries.
- Symptoms are characterized by central chest pain, discomfort, or breathlessness, precipitated by exertion or stress, and promptly relieved by rest.
- Activities that trigger angina include physical exertion, cold exposure, heavy meals, and intense emotions.
Unstable Angina/Non ST-elevation Myocardial Infarction (NSTEMI)
- Ischemia is caused by dynamic obstruction of a coronary artery due to plaque rupture with superimposed thrombosis and spasm.
- Characterized by new-onset severe angina, rapidly worsening angina, angina with minimal exertion or at rest.
- Differentiated from NSTEMI by the absence of elevated myocardial necrosis markers in the blood.
- Diagnosis relies on chest pain analysis, 12-lead ECG, and cardiac markers.
Myocardial Infarction (MI)
- Myocardial necrosis (tissue death) caused by acute occlusion (blocking) of a coronary artery.
- Occurs due to plaque rupture and thrombus formation.
- Characterized by severe and prolonged chest pain, potentially in the same sites as angina but usually more severe. Other symptoms can include breathlessness, vomiting, and collapse or syncope.
- Infarction progresses over several hours making prompt intervention crucial.
ST-Elevation Myocardial Infarction (STEMI)
- Complete occlusion of the coronary artery.
- Characterized by typical ECG changes and elevated plasma cardiac markers.
Investigations
- Stable Angina: Resting ECG, exercise ECG, myocardial perfusion scanning, stress echocardiography, coronary arteriography
- Unstable Angina/NSTEMI: Similar to stable angina, with additional focus on cardiac markers.
- STEMI: ECG changes including ST elevation and presence of elevated cardiac markers.
Management
- Stable Angina: Risk factor modification (blood pressure control, smoking cessation, weight loss, diabetes control), lifestyle modifications, aspirin, lipid-lowering therapy, anti-anginal therapy.
- Unstable Angina/NSTEMI: Urgent medical stabilization, and angiography.
- STEMI: Immediate access to medical/paramedical care, defibrillation facilities, bed rest, medication (aspirin, antiplatelets, anticoagulants, beta-blockers, calcium channel blockers).
Other Important Concepts
- Lipid Profile: Necessary for assessing risk and includes testing of TSCH, HDL, LDL, TG, and VLDL levels.
- Atherosclerosis: The buildup of plaque within the arteries, which narrows the lumen and reduces blood flow. This is a major contributor to CHD.
- Myocardial Oxygen Demand: Factors affecting need such as heart rate, blood pressure, and myocardial contraction.
- Myocardial Oxygen Supply: Factors affecting supply such as duration of diastole and coronary vasomotor tone (how constricted vessels are) which impact blood flow.
- Drug therapy: (antiplatelet, lipid-lowering, anti-anginal medication including nitrates, Beta-blockers, and Calcium channel blockers) are key aspects of managing CHD.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.