Podcast
Questions and Answers
Which hormone is produced by the hypothalamus to stimulate TSH release?
Which hormone is produced by the hypothalamus to stimulate TSH release?
What is the effect of increased free T4 and T3 levels on TRH and TSH secretion?
What is the effect of increased free T4 and T3 levels on TRH and TSH secretion?
Which gland produces thyroid-stimulating hormone?
Which gland produces thyroid-stimulating hormone?
What initiates the release of T4 and T3 hormones?
What initiates the release of T4 and T3 hormones?
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Which axis is involved in the control of T4 and T3 secretions?
Which axis is involved in the control of T4 and T3 secretions?
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Study Notes
Control of T4 and T3 Secretions
- Physiological control of T4 and T3 occurs through the hypothalamic-pituitary-thyroid axis
- Hypothalamic thyrotropin-releasing hormone (TRH) stimulates the release of thyroid-stimulating hormone (TSH) from the anterior pituitary gland
- TSH stimulates the release of thyroid hormones (T4 and T3)
- Increase in free T4 and free T3 causes negative feedback inhibition to this axis
- Negative feedback inhibition results in suppression of both TSH and TRH secretion
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Description
Learn about the physiological control of T4 and T3 hormone secretion through the hypothalamic-pituitary-thyroid axis and how negative feedback inhibition regulates their production.
