5 Questions
Which hormone is produced by the hypothalamus to stimulate TSH release?
Thyrotropin-releasing hormone
What is the effect of increased free T4 and T3 levels on TRH and TSH secretion?
Decreases TRH and TSH secretion
Which gland produces thyroid-stimulating hormone?
Anterior pituitary gland
What initiates the release of T4 and T3 hormones?
Stimulation by TSH from the pituitary gland
Which axis is involved in the control of T4 and T3 secretions?
Hypothalamic-pituitary-thyroid axis
Study Notes
Control of T4 and T3 Secretions
- Physiological control of T4 and T3 occurs through the hypothalamic-pituitary-thyroid axis
- Hypothalamic thyrotropin-releasing hormone (TRH) stimulates the release of thyroid-stimulating hormone (TSH) from the anterior pituitary gland
- TSH stimulates the release of thyroid hormones (T4 and T3)
- Increase in free T4 and free T3 causes negative feedback inhibition to this axis
- Negative feedback inhibition results in suppression of both TSH and TRH secretion
Learn about the physiological control of T4 and T3 hormone secretion through the hypothalamic-pituitary-thyroid axis and how negative feedback inhibition regulates their production.
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