Questions and Answers
What is the drug of choice for hypothyroidism?
In hypothyroidism, TSH levels are low.
False
In hyperthyroidism, TSH levels are low and T3/T4 levels are high.
True
What is the conversion process from T4 to T3?
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A TSH level of _____ or higher indicates the need for treatment in hypothyroidism.
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The typical dosage of Synthroid for adults is _____ mcg/kg/day.
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Study Notes
Thyroid Hormone Regulation
- Hypothalamus produces TRH, which stimulates the pituitary to release TSH, which in turn stimulates the thyroid gland to produce T4.
- T4 is converted to T3, the active metabolite, by the thyroid gland.
Hypothyroidism
- Characterized by high TSH levels and low T4 levels.
- Subclinical hypothyroidism may have normal T4 levels.
- Treatment is recommended if TSH level is above 10, starting with low dose.
Hyperthyroidism
- Characterized by low TSH levels and high T3/T4 levels.
- Subclinical hyperthyroidism may have normal T4 levels.
Hypothyroid Medications
- Synthroid is a synthetic preparation of T4 and the drug of choice for hypothyroidism.
- Synthroid is converted to T3 in the body.
- The recommended adult dosage is 1.6-1.8 mcg/kg/day.
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Test your knowledge on the regulation of thyroid hormones, including hypothyroidism and hyperthyroidism
