25 Questions
Which tissue is derived from mesoderm?
Connective tissue
What is the function of connective tissue?
Support and strengthen other tissues
What is the extracellular matrix made of?
Ground substance and fibers
Which cells are derived from mesenchyme?
Connective tissue cells
What type of cells have names that end in -cyte?
Mature cells
Which type of connective tissue has a gel-like consistency?
Loose connective tissue
Which tissue has a good nerve and blood supply except in cartilage and tendons?
Connective tissue
What is the main function of adipose tissue?
Store energy reserves
Which type of collagen forms fibres in the skin, bones, tendons, and ligaments?
Type I
What is the function of elastin and fibrillin?
To form fibres in the extracellular matrix
Which type of collagen forms networks in the basal lamina?
Type IV
Which type of collagen is associated with fibrils?
Type III
What is the main function of proteoglycan molecules in the extracellular matrix?
To form fibres
Which type of extracellular matrix fibre is good at resisting tensile forces?
Collagen
What is the function of collagen in the extracellular matrix?
To form fibres
Which type of extracellular matrix fibre forms networks in the basal lamina?
Collagen
Which type of collagen is responsible for anchoring the basement membrane to the epidermis?
Type VI
Which cells are the principal active cells of connective tissue?
Fibroblasts
Which cells store triglycerides and are found beneath the skin and around internal organs?
Adipocytes
Which cells form dentin forming odontoblasts, pulp, and periodontal ligament?
Mesenchymal cells
Which cells are modified fibroblasts that secrete collagen and can also contract?
Myofibroblasts
Which cells are pluripotent cells in the bone marrow that include macrophages, plasma cells, mast cells, neutrophils, and eosinophils?
Transitory cells
Which component of the extracellular matrix is good at resisting compressive forces and has a texture that can be fluid, semifluid, gelatinous, or calcified?
Ground substance
Which component of the ground substance captures water, turns the ground substance more jelly-like, and brings cells together, maintaining their shape and lubricating them?
Hyaluronic acid
Which component of the ground substance provides support and adhesiveness to cartilage, bone, skin, and blood vessels?
Glycosaminoglycans
Study Notes
Connective Tissue
- Connective tissue is derived from mesoderm.
- The function of connective tissue is to provide support, structure, and connectivity to the body.
Extracellular Matrix
- The extracellular matrix is made of ground substance, fibers, and cells.
- The ground substance is composed of proteoglycan molecules, hyaluronic acid, and chondroitin sulfate.
- Fibers in the extracellular matrix include collagen, elastin, and fibrillin.
Connective Tissue Cells
- Cells derived from mesenchyme include fibroblasts, adipocytes, chondrocytes, osteocytes, and odontoblasts.
- Cell types with names that end in -cyte include fibrocyte, adipocyte, chondrocyte, osteocyte, and odontoblast.
- Principal active cells of connective tissue include fibroblasts, macrophages, and mast cells.
- Fibroblasts are modified to form myofibroblasts, which can contract and secrete collagen.
- Pluripotent cells in the bone marrow include macrophages, plasma cells, mast cells, neutrophils, and eosinophils.
Connective Tissue Types
- Connective tissue with a gel-like consistency includes areolar tissue and mesenchyme.
- Connective tissue with a good nerve and blood supply, except in cartilage and tendons, includes loose and dense connective tissue.
- Adipose tissue stores triglycerides and is found beneath the skin and around internal organs.
- The main function of adipose tissue is to store energy.
Collagen
- Collagen type I forms fibers in the skin, bones, tendons, and ligaments.
- Collagen type IV forms networks in the basal lamina.
- Collagen type VII is associated with fibrils and anchors the basement membrane to the epidermis.
- The function of collagen is to provide strength, structure, and support to the extracellular matrix.
Other Components
- Elastin and fibrillin provide elasticity to the extracellular matrix.
- Proteoglycan molecules capture water, provide lubrication, and maintain tissue shape.
- Hyaluronic acid captures water, turning the ground substance into a jelly-like texture, and brings cells together.
- Chondroitin sulfate provides support and adhesiveness to cartilage, bone, skin, and blood vessels.
Test your knowledge on the general characteristics of connective tissue! This quiz covers topics such as the extracellular matrix, consistency, nerve and blood supply, and more. Challenge yourself and see how well you understand the key features of connective tissue.
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