Congenital & Acquired Bone Disorders Overview Quiz
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Questions and Answers

What is the primary age group in which Osteitis Deformans commonly begins?

  • Elderly population
  • Late adulthood (correct)
  • Teenage years
  • Early adulthood

In which regions is Paget Disease of the Bone more commonly prevalent?

  • Scandinavia and Japan
  • China and Africa
  • England and USA (correct)
  • France and Austria

What is the predominant bone involvement in Paget Disease of the Bone?

  • Facial bones
  • Peripheral bones
  • Long bones
  • Axial skeleton or proximal femur (correct)

What is the main reason for pain experienced by individuals with Paget Disease of the Bone?

<p>Microfractures (B)</p> Signup and view all the answers

What is a potential long-term complication associated with Paget Disease of the Bone?

<p>Osteosarcoma (B)</p> Signup and view all the answers

Which bone disorder is characterized by decreased bone mass but not severe enough to significantly increase the risk of fracture?

<p>Osteopenia (C)</p> Signup and view all the answers

In advanced osteoporosis, which bone component is markedly thinned?

<p>Trabecular bone of the medulla (A)</p> Signup and view all the answers

What is the most common skeletal dysplasia that is a major cause of dwarfism?

<p>Achondroplasia (A)</p> Signup and view all the answers

Which condition can cause significant loss of height and deformities like lumbar lordosis and kyphoscoliosis?

<p>Vertebral fractures (C)</p> Signup and view all the answers

Which gene mutation is responsible for Achondroplasia, the most common skeletal dysplasia?

<p>Mutations in fibroblast growth factor receptor 3 (FGFR3) (A)</p> Signup and view all the answers

What is the best screening method for diagnosing osteoporosis?

<p>Dual-energy x-ray absorptiometry (DEXA scan) (B)</p> Signup and view all the answers

Which type of Osteogenesis imperfecta variant is fatal either in utero or during the perinatal period?

<p>Type 2 variant (C)</p> Signup and view all the answers

Which condition results in increased osteoclast activity, bone resorption, osteopenia, and osteoporosis?

<p>Hyperparathyroidism (D)</p> Signup and view all the answers

What is the average yearly loss of bone mass in postmenopausal women with osteoporosis?

<p>0.7% of cortical bone and 2% of medullary bone (B)</p> Signup and view all the answers

What is the manifestation of vitamin D deficiency that interferes with bone deposition in growth plates?

<p>Rickets (B)</p> Signup and view all the answers

Which disorder involves extreme skeletal fragility due to mutations in genes encoding type I collagen chains?

<p>Osteogenesis imperfecta (A)</p> Signup and view all the answers

Which condition presents with cystic degeneration of brown tumors with increased fibrosis?

<p>Paget disease of the bone (B)</p> Signup and view all the answers

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