Congenital & Acquired Bone Disorders Overview Quiz
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Questions and Answers

What is the primary age group in which Osteitis Deformans commonly begins?

  • Elderly population
  • Late adulthood (correct)
  • Teenage years
  • Early adulthood
  • In which regions is Paget Disease of the Bone more commonly prevalent?

  • Scandinavia and Japan
  • China and Africa
  • England and USA (correct)
  • France and Austria
  • What is the predominant bone involvement in Paget Disease of the Bone?

  • Facial bones
  • Peripheral bones
  • Long bones
  • Axial skeleton or proximal femur (correct)
  • What is the main reason for pain experienced by individuals with Paget Disease of the Bone?

    <p>Microfractures</p> Signup and view all the answers

    What is a potential long-term complication associated with Paget Disease of the Bone?

    <p>Osteosarcoma</p> Signup and view all the answers

    Which bone disorder is characterized by decreased bone mass but not severe enough to significantly increase the risk of fracture?

    <p>Osteopenia</p> Signup and view all the answers

    In advanced osteoporosis, which bone component is markedly thinned?

    <p>Trabecular bone of the medulla</p> Signup and view all the answers

    What is the most common skeletal dysplasia that is a major cause of dwarfism?

    <p>Achondroplasia</p> Signup and view all the answers

    Which condition can cause significant loss of height and deformities like lumbar lordosis and kyphoscoliosis?

    <p>Vertebral fractures</p> Signup and view all the answers

    Which gene mutation is responsible for Achondroplasia, the most common skeletal dysplasia?

    <p>Mutations in fibroblast growth factor receptor 3 (FGFR3)</p> Signup and view all the answers

    What is the best screening method for diagnosing osteoporosis?

    <p>Dual-energy x-ray absorptiometry (DEXA scan)</p> Signup and view all the answers

    Which type of Osteogenesis imperfecta variant is fatal either in utero or during the perinatal period?

    <p>Type 2 variant</p> Signup and view all the answers

    Which condition results in increased osteoclast activity, bone resorption, osteopenia, and osteoporosis?

    <p>Hyperparathyroidism</p> Signup and view all the answers

    What is the average yearly loss of bone mass in postmenopausal women with osteoporosis?

    <p>0.7% of cortical bone and 2% of medullary bone</p> Signup and view all the answers

    What is the manifestation of vitamin D deficiency that interferes with bone deposition in growth plates?

    <p>Rickets</p> Signup and view all the answers

    Which disorder involves extreme skeletal fragility due to mutations in genes encoding type I collagen chains?

    <p>Osteogenesis imperfecta</p> Signup and view all the answers

    Which condition presents with cystic degeneration of brown tumors with increased fibrosis?

    <p>Paget disease of the bone</p> Signup and view all the answers

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