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Questions and Answers
Which of the following complete blood count (CBC) findings suggests a condition characterized by an increased number of red blood cells?
Which of the following complete blood count (CBC) findings suggests a condition characterized by an increased number of red blood cells?
- Anemia
- Thrombocytopenia
- Polycythemia (correct)
- Leukocytosis
Hematocrit can be directly measured using a hemocytometer.
Hematocrit can be directly measured using a hemocytometer.
False (B)
A differential diagnosis (DDx) list is used primarily to:
A differential diagnosis (DDx) list is used primarily to:
- Pinpoint a diagnosis based on suggested diagnostic tests. (correct)
- Identify the types of white blood cells present.
- Measure the size of red blood cells.
- Count the number of platelets in a blood sample.
Which diagnostic method uses an x-y diagram for two antigens to identify the neoplastic cell of origin?
Which diagnostic method uses an x-y diagram for two antigens to identify the neoplastic cell of origin?
What is one hematologic manifestation of HIV infection mentioned?
What is one hematologic manifestation of HIV infection mentioned?
NRBCs and reticulocytes are used in RBC histograms to identify compensatory ______.
NRBCs and reticulocytes are used in RBC histograms to identify compensatory ______.
Match the following leukemia with its abbreviation:
Match the following leukemia with its abbreviation:
Besides anemia/polycythemia, leukocytosis/leukopenia and thrombocytopenia/thrombocytosis, which of the following conditions can be identified using virtual slides and CBCs?
Besides anemia/polycythemia, leukocytosis/leukopenia and thrombocytopenia/thrombocytosis, which of the following conditions can be identified using virtual slides and CBCs?
Identifying karyotypes is not useful for classifying lymphomas.
Identifying karyotypes is not useful for classifying lymphomas.
What is used, besides photomicrographs and virtual slides, to identify disease processes?
What is used, besides photomicrographs and virtual slides, to identify disease processes?
Flashcards
What is a Complete Blood Count (CBC)?
What is a Complete Blood Count (CBC)?
A blood test to evaluate overall health, including red blood cells, white blood cells, and platelets.
What is hematocrit?
What is hematocrit?
The percentage of blood volume occupied by red blood cells.
What is hemoglobin?
What is hemoglobin?
The oxygen-carrying protein found in red blood cells.
What is differential diagnosis (DDx)?
What is differential diagnosis (DDx)?
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What is flow cytometry?
What is flow cytometry?
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What is Karyotyping?
What is Karyotyping?
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What is polycythemia?
What is polycythemia?
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What is anemia?
What is anemia?
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Study Notes
- Able to read and interpret a CBC, which includes the clinical significance of abnormal findings
- Polycythemia/anemia can be microcytic, normocytic, or macrocytic
- Hemolytic anemia involves schistocytes and spherocytes
- Compensatory hematopoiesis uses RBC histogram and includes nRBCs and reticulocytes
- Leukopenia/leukocytosis includes neutrophilia, eosinophilia, basophilia, lymphocytosis, and monocytosis
- Thrombocytopenia/thrombocytosis must be understood
- Must know the normal hematocrit and hemoglobin ranges for males and females
- Know the actual molecule measured by the Hemocue
- Know how to determine hematocrit from a capillary tube of centrifuged blood
- Suggest additional diagnostic tests to pinpoint a diagnosis from provided differential diagnosis (DDx) list
Flow Cytometry
- Able to interpret a flow cytometry x-y diagram for two antigens
- Use flow cytometry results to identify the neoplastic cell of origin for acute leukemias (ALL, AML), chronic leukemias (CLL, CML, ET, PV), aplastic anemia (AA), myelodysplasia (MDS), lymphomas (Hodgkin, follicular, diffuse large B cell) and myeloma
- Interpret hematologic manifestations of HIV infection
Disease Identification
- Identify diseases on three microscope slides from among IDA, SCD, ALL, AML, IM, CLL, ET, CML, HL, FL, DLBCL, MM, AA
- Answer questions regarding the corresponding disease processes
Unknown Disease Identification
- Apply knowledge to identify a disease process in one unknown slide
- Use characteristic features, photomicrographs, virtual slides, and CBCs to identify sepsis, MBA, IDA, SCD, HDFN, ALL, AML, IM, CLL, ET, PV, CML, HL, FL, DLBCL, MM, AA
- Answer questions regarding the corresponding disease processes
Karyotypes
- Recognize characteristic karyotypes for CML, acute leukemia/Hodgkin lymphoma (complex karyotype), myeloma/Burkitt lymphoma, follicular lymphoma
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