18 Questions
Complement component C5 is associated with recurrent bacterial infections.
False
The Classical Pathway of the Complement system can be triggered by Mannose-binding lectin (MBL).
False
Deficiency in complement component C3 can lead to an increased susceptibility to a wide range of bacterial infections.
True
Complement component C1 is associated with autoimmune diseases like Systemic Lupus Erythematosus (SLE).
True
Opsonization is a clinical manifestation of the complement system in immunity.
False
The Lectin Pathway of the Complement system is triggered by spontaneous hydrolysis of C3 in the blood stream.
False
The complement system consists of 30 soluble and membrane-bound proteins.
True
In the complement system, proteins are designated with a letter followed by numbers like A1 to A9.
False
The complement system is only involved in innate immunity, not adaptive immunity.
False
Opsonization is the process of removing complement proteins from the body.
False
Activated complement components are designated by adding the letter 'a' to the symbols.
True
In the complement system, a cascade of proteins refers to a series of biochemical reactions where each protein inhibits the next one.
False
During T cell development, thymocytes originate from the spleen.
False
Thymocytes migrate to the liver for T cell development.
False
DP thymocytes express only CD4 receptor during early thymocyte development.
False
Thymocytes that fail to undergo positive selection undergo proliferation.
False
Positive selection in T cell developmental stages occurs when DP thymocytes recognize self-MHC molecules.
True
Negative selection in T cell development leads to autoimmunity.
False
Test your knowledge on the different pathways of the complement system activation, including the Classical, Lectin, and Alternative pathways. Explore how each pathway is triggered and the mechanisms involved in activating the immune response.
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