Complement System Activation Pathways Quiz

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18 Questions

Complement component C5 is associated with recurrent bacterial infections.

False

The Classical Pathway of the Complement system can be triggered by Mannose-binding lectin (MBL).

False

Deficiency in complement component C3 can lead to an increased susceptibility to a wide range of bacterial infections.

True

Complement component C1 is associated with autoimmune diseases like Systemic Lupus Erythematosus (SLE).

True

Opsonization is a clinical manifestation of the complement system in immunity.

False

The Lectin Pathway of the Complement system is triggered by spontaneous hydrolysis of C3 in the blood stream.

False

The complement system consists of 30 soluble and membrane-bound proteins.

True

In the complement system, proteins are designated with a letter followed by numbers like A1 to A9.

False

The complement system is only involved in innate immunity, not adaptive immunity.

False

Opsonization is the process of removing complement proteins from the body.

False

Activated complement components are designated by adding the letter 'a' to the symbols.

True

In the complement system, a cascade of proteins refers to a series of biochemical reactions where each protein inhibits the next one.

False

During T cell development, thymocytes originate from the spleen.

False

Thymocytes migrate to the liver for T cell development.

False

DP thymocytes express only CD4 receptor during early thymocyte development.

False

Thymocytes that fail to undergo positive selection undergo proliferation.

False

Positive selection in T cell developmental stages occurs when DP thymocytes recognize self-MHC molecules.

True

Negative selection in T cell development leads to autoimmunity.

False

Test your knowledge on the different pathways of the complement system activation, including the Classical, Lectin, and Alternative pathways. Explore how each pathway is triggered and the mechanisms involved in activating the immune response.

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