Competitive Inhibitors of Dihydropteroate Synthetase
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Questions and Answers

What is the mechanism of action of the drug that competitively inhibits dihydropteroate synthetase?

The drug blocks the enzyme dihydropteroate synthetase, which is necessary for the synthesis of folic acid in bacteria.

What is the significance of inhibiting dihydropteroate synthetase in bacterial cells?

Inhibiting dihydropteroate synthetase leads to the inability of bacteria to synthesize folic acid, which is essential for their survival and reproduction.

What are some examples of bacterial infections that can be treated with drugs that inhibit dihydropteroate synthetase?

Some examples include urinary tract infections, respiratory tract infections, and skin infections caused by susceptible bacteria such as Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus.

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