Common Neonatal Presentation: Jaundice
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Questions and Answers

What is the primary cause of hyperbilirubinemia in newborns?

  • Excessive production of hemoglobin
  • Accumulation of excess bilirubin in blood serum (correct)
  • Complete failure of the liver
  • Inadequate intake of nutrients
  • Which of the following statements about unconjugated bilirubin is true?

  • It is a breakdown product of hemoglobin. (correct)
  • It is the primary form found in the urine.
  • It cannot cause kernicterus.
  • It is water soluble and does not cross the blood-brain barrier.
  • What percentage of healthy infants typically develop physiological jaundice within the first week of life?

  • 70%
  • 30%
  • 50%
  • 60% (correct)
  • Which investigation is NOT typically performed when assessing jaundice in neonates?

    <p>Magnetic resonance imaging (MRI)</p> Signup and view all the answers

    What is the wavelength range of blue fluorescent lights used in phototherapy for neonatal jaundice?

    <p>430–490nm</p> Signup and view all the answers

    Which of the following is a high-risk factor for physiological jaundice?

    <p>Sepsis</p> Signup and view all the answers

    What is an appropriate action if a baby requires exchange transfusion?

    <p>Keep the baby nil by mouth</p> Signup and view all the answers

    Which symptom is NOT typically associated with the side effects mentioned?

    <p>Hives</p> Signup and view all the answers

    What must be monitored for infants discharged before 48 hours?

    <p>Follow-up care</p> Signup and view all the answers

    What is a major concern that can lead to dehydration in infants?

    <p>Underfeeding</p> Signup and view all the answers

    What type of medical cause can lead to poor feeding in infants?

    <p>Upper respiratory tract infection (URTI)</p> Signup and view all the answers

    What should be taught to caregivers regarding hydration?

    <p>Signs of dehydration</p> Signup and view all the answers

    What is a consequence of increased insensible water loss?

    <p>Possible dehydration</p> Signup and view all the answers

    What is the primary purpose of phototherapy in managing jaundice?

    <p>To reduce bilirubin levels by promoting its conversion</p> Signup and view all the answers

    What is a crucial factor to ensure when administering phototherapy?

    <p>Ensure adequate hydration with wet diapers</p> Signup and view all the answers

    Which bilirubin type is primarily increased in jaundice (hyperbilirubinemia)?

    <p>Unconjugated Bilirubin</p> Signup and view all the answers

    What is the recommended frequency for turning a baby during single blue phototherapy?

    <p>Every two to three hours</p> Signup and view all the answers

    What is a recommended practice to protect an infant's eyes during phototherapy?

    <p>Use eye covers</p> Signup and view all the answers

    Under what condition is double blue phototherapy recommended?

    <p>If the bilirubin level is high or rapidly increasing</p> Signup and view all the answers

    What mechanism allows bilirubin to be excreted via urine and stool?

    <p>Conjugation by glucuronyl transferase</p> Signup and view all the answers

    What is the ideal hemoglobin level for fetal hemoglobin in newborns?

    <p>18-20 g/dl</p> Signup and view all the answers

    Study Notes

    Common Neonatal Presentation

    • Neonatal jaundice is characterized by hyperbilirubinemia, an excess of bilirubin in blood serum.
    • Unconjugated bilirubin results from the breakdown of hemoglobin; it is lipid-soluble and capable of crossing the blood-brain barrier.
    • Kernicterus refers to bilirubin-induced brain damage, leading to cerebral palsy; symptoms include lethargy, poor feeding, abnormal tone, a high-pitched cry, and irritability.

    Physiological Jaundice

    • Approximately 60% of healthy newborns exhibit jaundice in the first week of life.
    • Diagnosis is considered if jaundice appears after 24-36 hours of age, should worsen with a rate of rise >5 μmol/L/hr, and usually resolves by 14 days.

    Investigations for Jaundice

    • Serum bilirubin levels must be checked when transcutaneous bilirubin (TcB) reaches critical thresholds.
    • A complete blood count (CBC), reticulocyte count, and direct Coombs test assess for hemolysis.
    • Additional tests like urea, electrolytes, creatinine, and serum albumin facilitate dehydration management.

    Phototherapy Treatment

    • Phototherapy involves exposing a baby’s skin to blue fluorescent lights (430-490nm) to convert bilirubin into a more excretable form.
    • To enhance treatment, provide maximum skin exposure to the light settings, ensuring the baby is adequately hydrated.
    • Monitor urine and stool color and check skin integrity throughout treatment.

    Types of Phototherapy

    • Single Blue Phototherapy: One plane of the body is treated by turning the baby every 2-3 hours, ensuring warmth, and monitoring vital signs.
    • Double Blue Phototherapy: Exposes both front and back simultaneously; indicated if serum bilirubin levels exceed safe limits or if bilirubin rise is rapid, although it may cause temperature instability and increased water loss.

    Feeding During Phototherapy

    • Feeding should continue unless exchange transfusion is necessary; increase feeds by at least 10% of expected intake.
    • Babies can be briefly removed from phototherapy for feeding if bilirubin levels are manageable.
    • Educate caregivers about signs of dehydration and the importance of follow-up appointments, especially for early discharges.

    Risk Factors for Jaundice

    • Low Risk: Typically, physiological jaundice in healthy infants.
    • High Risk: Factors include preterm birth, hemolytic conditions, sepsis, and dehydration.

    Medical and Surgical Causes

    • Potential infections include upper respiratory infections, gastroenteritis, urinary tract infections, and meningitis.
    • Surgical issues could entail hernias, trauma, or intestinal blockages.
    • Monitor for signs of non-accidental injury (NAI), abnormal laboratory findings, and parental stress that may complicate the infant's care.

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    Description

    Explore the critical aspects of neonatal jaundice through this quiz. Learn about hyperbilirubinemia, its assessment, and the principles of phototherapy in managing this condition. Enhance your understanding of how excess bilirubin can impact neonatal health.

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