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Questions and Answers
A patient presents with a chronic nail infection characterized by thickening, discoloration, and brittleness. Which etiological agent and treatment strategy would be most appropriate?
A patient presents with a chronic nail infection characterized by thickening, discoloration, and brittleness. Which etiological agent and treatment strategy would be most appropriate?
- Epidermophyton floccosum, treated effectively with topical clotrimazole alone.
- Microsporum audouinii, best managed with short-term itraconazole applications.
- Trichophyton rubrum, requiring a prolonged course of oral terbinafine. (correct)
- Trichophyton mentagrophytes, typically resolving spontaneously with improved hygiene.
A dermatologist examines a patient with circular, scaly lesions on the trunk exhibiting central clearing and an inflamed periphery. Which diagnostic and management steps are most appropriate for this condition?
A dermatologist examines a patient with circular, scaly lesions on the trunk exhibiting central clearing and an inflamed periphery. Which diagnostic and management steps are most appropriate for this condition?
- Obtain a skin scraping for microscopic examination and initiate oral griseofulvin therapy. (correct)
- Recommend keeping the area dry and exposed to sunlight to inhibit fungal growth.
- Advise on the use of topical corticosteroids to reduce inflammation and itching.
- Prescribe a broad-spectrum antibiotic to address potential bacterial involvement.
Healthcare workers should be particularly diligent about implementing which of the following infection control measures to prevent the transmission of cutaneous mycoses?
Healthcare workers should be particularly diligent about implementing which of the following infection control measures to prevent the transmission of cutaneous mycoses?
- Routine vaccination against common dermatophytes for high-risk populations.
- Isolating patients with fungal infections in negative pressure rooms.
- Ensuring thorough disinfection of shared equipment and surfaces. (correct)
- Administering prophylactic antibiotics to all patients with skin conditions.
How does the unique metabolic capability of dermatophytes contribute to their pathogenic mechanism in cutaneous infections?
How does the unique metabolic capability of dermatophytes contribute to their pathogenic mechanism in cutaneous infections?
A patient is diagnosed with Tinea capitis due to Microsporum infection. What clinical findings would be most indicative of this specific etiology?
A patient is diagnosed with Tinea capitis due to Microsporum infection. What clinical findings would be most indicative of this specific etiology?
Which of the following factors would be MOST significant in predisposing an individual to the development of Tinea cruris?
Which of the following factors would be MOST significant in predisposing an individual to the development of Tinea cruris?
Following diagnosis of Tinea pedis, a patient is prescribed topical antifungal medication. What additional advice should the healthcare provider offer to enhance treatment efficacy and prevent recurrence?
Following diagnosis of Tinea pedis, a patient is prescribed topical antifungal medication. What additional advice should the healthcare provider offer to enhance treatment efficacy and prevent recurrence?
What key difference distinguishes dermatophytes from other types of fungi that cause systemic mycoses?
What key difference distinguishes dermatophytes from other types of fungi that cause systemic mycoses?
What is the MOST critical factor in determining the appropriate duration of treatment for onychomycosis?
What is the MOST critical factor in determining the appropriate duration of treatment for onychomycosis?
A patient with Tinea capitis is treated with oral griseofulvin but shows no improvement after several weeks. How should the treatment strategy be adapted?
A patient with Tinea capitis is treated with oral griseofulvin but shows no improvement after several weeks. How should the treatment strategy be adapted?
Flashcards
Dermatophytes
Dermatophytes
Fungi that infect keratinized tissues (skin, hair, nails).
Tinea Pedis
Tinea Pedis
Fungal infection, often between toes, caused by Trichophyton species.
Tinea Corporis
Tinea Corporis
Ring-shaped fungal lesions caused by Epidermophyton, Trichophyton, or Microsporum.
Tinea Capitis
Tinea Capitis
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Tinea Cruris
Tinea Cruris
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Tinea Unguium (Onychomycosis)
Tinea Unguium (Onychomycosis)
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Treatment for Dermatophytosis
Treatment for Dermatophytosis
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Dermatophytes Characteristic
Dermatophytes Characteristic
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Study Notes
- Common cutaneous diseases arise from related fungi known as dermatophytes.
- Dermatophytes infect keratinized tissues, including skin, hair, and nails, causing superficial infections.
- The three genera of dermatophytes are Trichophyton, Epidermophyton, and Microsporum, each consisting of many species.
Tinea Pedis (Athlete's Foot)
- Commonly isolated fungi include Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum.
- Initially, infection occurs between the toes, potentially spreading to the nails and causing them to become yellow and brittle.
- Skin fissures can lead to secondary bacterial infections, resulting in lymph node inflammation.
- Moisture from foot sweating promotes fungal growth.
Tinea Corporis (Ringworm)
- Epidermophyton, Trichophyton, and Microsporum are the most frequently isolated fungi.
- Lesions manifest as rings that expand with scaly centers.
- The ring's periphery, which contains active fungal growth, is typically inflamed and vesiculated.
- Lesions commonly appear on non-hairy areas of the trunk, including the iliac side, though any body site can be affected.
Tinea Capitis (Scalp Ringworm)
- Several Trichophyton and Microsporum species are isolated from scalp ringworm lesions.
- In the United States, the predominant infecting species is Trichophyton tonsurans.
- Disease manifestations range from small scaling patches to extensive hair loss involving the entire scalp.
- Microsporum hyphae can infect hair shafts, which can be detected by green fluorescence under Wood's lamp (long-wave ultraviolet light).
Tinea Cruris (Jock Itch)
- Epidermophyton floccosum and Trichophyton rubrum are the causative organisms.
- Disease manifestations resemble tinea pedis, but lesions occur in moist groin areas.
- Lesions can spread from the upper thigh to the genitals.
Tinea Unguium (Onychomycosis)
- Trichophyton rubrum causes tinea unguium.
- The nails thicken, become discolored, and brittle.
- Treatment must continue for three to four months until all infected portions of the nail have grown out and are trimmed off.
Treatment
- Initial treatment involves removing infected skin, followed by topical application of antifungal drugs like itraconazole and clotrimazole.
- Refractory or resistant infections typically respond well to oral treatments like terbinafine and griseofulvin.
- Terbinafine is the preferred drug for onychomycosis.
Transmission & Characteristics
- Cutaneous mycoses are transmitted from human to human or animal to human via infected skin scales on inanimate objects.
- Dermatophytes can utilize keratin as a source of nutrition.
- This ability allows them to invade keratinized tissues and structures such as skin, hair, and nails.
- They do not invade underlying non-keratinized tissue.
- Dermatophytes cause itching, scaly skin patches that can become inflamed and vesicular/weeping.
- Specific diseases are usually identified according to the affected tissue, such as the scalp, pubic area, or feet.
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