Podcast
Questions and Answers
What is the function of proteoglycans in the Extra-Cellular Matrix (ECM)?
What is the function of proteoglycans in the Extra-Cellular Matrix (ECM)?
- Confer lubrication and hydration (correct)
- Serve as reservoirs for growth factors
- Regulate cell proliferation
- Provide mechanical support to tissues
Which component of the ECM is a major constituent of the basement membrane?
Which component of the ECM is a major constituent of the basement membrane?
- Laminin (correct)
- Elastin
- Collagens
- Fibronectin
What is critical to the development of strength in a healing wound site?
What is critical to the development of strength in a healing wound site?
- Macrophage response
- Collagen synthesis (correct)
- ECM degradation
- Fibroblast activity
What is the main role of an intact ECM in tissue regeneration?
What is the main role of an intact ECM in tissue regeneration?
What family of enzymes is responsible for the degradation of collagens and other ECM components?
What family of enzymes is responsible for the degradation of collagens and other ECM components?
When does repair by connective tissue occur?
When does repair by connective tissue occur?
What is characteristic of granulation tissue during healing?
What is characteristic of granulation tissue during healing?
Which type of collagenases cleave fibrillar collagen like type 1, 2, and 3?
Which type of collagenases cleave fibrillar collagen like type 1, 2, and 3?
What process should be controlled for the proper remodeling of connective tissue?
What process should be controlled for the proper remodeling of connective tissue?
Which molecule is stored in the basement membrane for quick involvement in healing after local injury?
Which molecule is stored in the basement membrane for quick involvement in healing after local injury?
Healing by second intention involves:
Healing by second intention involves:
What type of wound healing involves cell or tissue loss that is more extensive?
What type of wound healing involves cell or tissue loss that is more extensive?
What process is characterized by the proliferation of fibroblasts and new delicate capillaries?
What process is characterized by the proliferation of fibroblasts and new delicate capillaries?
Which factor is responsible for the migration and proliferation of fibroblasts?
Which factor is responsible for the migration and proliferation of fibroblasts?
What is the result of the deposition of extracellular matrix (ECM) by fibroblasts?
What is the result of the deposition of extracellular matrix (ECM) by fibroblasts?
Which process allows tumors to grow beyond their original blood supply?
Which process allows tumors to grow beyond their original blood supply?
What factors are responsible for the migration of endothelial cells during tissue repair?
What factors are responsible for the migration of endothelial cells during tissue repair?
Which factor suppresses the proliferation and migration of endothelial cells during repair processes?
Which factor suppresses the proliferation and migration of endothelial cells during repair processes?
