Collagen Cross-link Formation and Lysyl Oxidase
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Questions and Answers

What percentage of the total protein of mammals does collagen constitute?

  • 40 to 50%
  • 60 to 70%
  • 25 to 35% (correct)
  • 15 to 20%
  • What is the primary structural component of tendons and cornea?

  • Type I collagen (correct)
  • Type III collagen
  • Type IV collagen
  • Type II collagen
  • Which type of collagen is primarily found in cartilaginous structures?

  • Type II collagen (correct)
  • Type III collagen
  • Type I collagen
  • Type IV collagen
  • What is the primary function of type IV collagen?

    <p>Providing mechanical support for cells</p> Signup and view all the answers

    What is the characteristic of type III collagen fibers?

    <p>High distensibility</p> Signup and view all the answers

    Which type of collagen is classified as fibril-associated collagen?

    <p>Type IX collagen</p> Signup and view all the answers

    Which enzyme oxidatively deaminates lysine and hydroxylysine residues in collagen?

    <p>Lysyl oxidase</p> Signup and view all the answers

    What is a characteristic feature of skin in Ehlers-Danlos syndrome?

    <p>Skin hyperextensibility</p> Signup and view all the answers

    Which type of collagen is most commonly defective in the classic form of Ehlers-Danlos syndrome?

    <p>Type V collagen</p> Signup and view all the answers

    What is the primary function of elastin in connective tissue?

    <p>Maintaining tissue elasticity</p> Signup and view all the answers

    What is the main characteristic of osteogenesis imperfecta?

    <p>Bone fragility</p> Signup and view all the answers

    Which of the following is NOT a clinical manifestation of Ehlers-Danlos syndrome?

    <p>Muscle weakness</p> Signup and view all the answers

    What is the primary function of elastin in the extracellular matrix?

    <p>To allow for elasticity and flexibility in connective tissue</p> Signup and view all the answers

    What is the underlying cause of osteogenesis imperfecta?

    <p>Genetic mutations in the synthesis of collagen</p> Signup and view all the answers

    Which of the following is a characteristic of collagen?

    <p>It is the most abundant protein in the human body</p> Signup and view all the answers

    What is the name of the group of genetic disorders caused by defects in specific components of proteoglycans?

    <p>Mucopolysaccharidoses</p> Signup and view all the answers

    Ehlers-Danlos syndrome is a connective tissue disorder characterized by?

    <p>Hyperextensible skin and joint hypermobility</p> Signup and view all the answers

    What is the primary function of fibronectin in the extracellular matrix?

    <p>To facilitate cell signaling and adhesion</p> Signup and view all the answers

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