Coating of Tablets and Multiparticulates Quiz
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Questions and Answers

What is the primary purpose of coating tablets and multiparticulates?

  • To improve the appearance of the product
  • To provide protection from the environment (correct)
  • To increase the cost of the product
  • To enhance the taste of the drug

Which type of coating is used to protect the drug from the acidic environment of the stomach?

  • Sugar coating
  • Extended release coating
  • Film coating
  • Enteric coating (correct)

What is the MAIN purpose of coating tablets and multiparticulates to modify drug release?

  • To mask the taste, odor or color of the drug
  • To provide delayed or extended release properties (correct)
  • To improve the appearance of the product
  • To increase the cost of the product

Which of the following is NOT a reason for coating tablets and multiparticulates?

<p>To increase the bioavailability of the drug (B)</p> Signup and view all the answers

Which type of coating is typically used for capsules?

<p>Sugar coating (C)</p> Signup and view all the answers

Which of the following is a benefit of coating tablets and multiparticulates to aid in product identification?

<p>Allows for the use of colored coatings (B)</p> Signup and view all the answers

What is the main purpose of press (compression) coating for tablets?

<p>To enable modified or controlled release of the drug (B)</p> Signup and view all the answers

How does the appearance of press (compression) coated tablets differ from sugar coated tablets?

<p>Press coated tablets retain the contour of the original core (C)</p> Signup and view all the answers

Which of the following is a key difference between press (compression) coating and film coating?

<p>Press coating is a single stage process, while film coating is a multistage process (C)</p> Signup and view all the answers

What is the typical weight increase of tablets due to press (compression) coating?

<p>30-50% (C)</p> Signup and view all the answers

Which coating method is considered the most modern and generally used nowadays?

<p>Film coating (C)</p> Signup and view all the answers

What is the primary purpose of using functional coatings in film coating?

<p>To enable modified or controlled release of the drug (C)</p> Signup and view all the answers

What is one of the advantages of film coating mentioned in the text?

<p>Single-stage application (C)</p> Signup and view all the answers

Why is polymer solubility important for film forming coatings?

<p>It affects the behavior of the coating in the GIT (D)</p> Signup and view all the answers

What type of solubility do film coating polymers used in immediate release products generally have?

<p>High solubility in aqueous fluids (C)</p> Signup and view all the answers

Why should polymers applied as solutions for film coating have relatively low viscosity?

<p>To simplify product transfer during coating (D)</p> Signup and view all the answers

How can film coating help optimize the shelf-life of a tablet preparation?

<p>By acting as an efficient barrier against water vapor or other gases (A)</p> Signup and view all the answers

What is one ideal characteristic of a film forming polymer to optimize shelf-life?

<p>Low permeability to atmospheric gases (A)</p> Signup and view all the answers

What is a disadvantage of using organic solvents?

<p>Environmental side effects (B)</p> Signup and view all the answers

Which of the following is an example of an aqueous polymeric dispersion?

<p>Aquacoat® cPD (B)</p> Signup and view all the answers

What is one of the fundamental requirements of a tablet coating system?

<p>Adequate mixing and agitation of the tablet bed (D)</p> Signup and view all the answers

Which polymer is used for sustained release coating?

<p>Methylmethacrylate (B)</p> Signup and view all the answers

What is a benefit of using water as a solvent in modern techniques?

<p>Lower environmental impact (D)</p> Signup and view all the answers

Why are specialized dispersions of water insoluble polymers frequently used industrially?

<p>To allow aqueous processing of water-insoluble polymers (C)</p> Signup and view all the answers

What is the first step in the pan coating process?

<p>Charge the pan with tablets and operate the drying air and exhaust (B)</p> Signup and view all the answers

What is the purpose of controlling the air and temperature during the pan coating process?

<p>To allow uniform spread of the coating solution before drying (C)</p> Signup and view all the answers

Which of the following is NOT a process variable in the pan coating process?

<p>Type of coating solution used (D)</p> Signup and view all the answers

Which of the following is NOT an ideal characteristic of film-coated tablets?

<p>Uniform tablet weight and size (A)</p> Signup and view all the answers

What is the purpose of the fluidized-bed (air suspension) coating technique?

<p>To keep the tablets in motion during the coating process (A)</p> Signup and view all the answers

Which of the following is NOT one of the two basic systems used to apply a finely divided (atomized) spray onto tablets?

<p>Ultrasonic atomization (A)</p> Signup and view all the answers

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