Coating of Tablets and Multiparticulates Quiz

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What is the primary purpose of coating tablets and multiparticulates?

To improve the appearance of the product

To provide protection from the environment (correct)

To increase the cost of the product

To enhance the taste of the drug

Which type of coating is used to protect the drug from the acidic environment of the stomach?

Sugar coating

Extended release coating

Film coating

Enteric coating (correct)

What is the MAIN purpose of coating tablets and multiparticulates to modify drug release?

To mask the taste, odor or color of the drug

To provide delayed or extended release properties (correct)

To improve the appearance of the product

To increase the cost of the product

Which of the following is NOT a reason for coating tablets and multiparticulates?

To increase the bioavailability of the drug (B) Signup and view all the answers

Which type of coating is typically used for capsules?

Sugar coating (C) Signup and view all the answers

Which of the following is a benefit of coating tablets and multiparticulates to aid in product identification?

Allows for the use of colored coatings (B) Signup and view all the answers

What is the main purpose of press (compression) coating for tablets?

To enable modified or controlled release of the drug (B) Signup and view all the answers

How does the appearance of press (compression) coated tablets differ from sugar coated tablets?

Press coated tablets retain the contour of the original core (C) Signup and view all the answers

Which of the following is a key difference between press (compression) coating and film coating?

Press coating is a single stage process, while film coating is a multistage process (C) Signup and view all the answers

What is the typical weight increase of tablets due to press (compression) coating?

30-50% (C) Signup and view all the answers

Which coating method is considered the most modern and generally used nowadays?

Film coating (C) Signup and view all the answers

What is the primary purpose of using functional coatings in film coating?

To enable modified or controlled release of the drug (C) Signup and view all the answers

What is one of the advantages of film coating mentioned in the text?

Single-stage application (C) Signup and view all the answers

Why is polymer solubility important for film forming coatings?

It affects the behavior of the coating in the GIT (D) Signup and view all the answers

What type of solubility do film coating polymers used in immediate release products generally have?

High solubility in aqueous fluids (C) Signup and view all the answers

Why should polymers applied as solutions for film coating have relatively low viscosity?

To simplify product transfer during coating (D) Signup and view all the answers

How can film coating help optimize the shelf-life of a tablet preparation?

By acting as an efficient barrier against water vapor or other gases (A) Signup and view all the answers

What is one ideal characteristic of a film forming polymer to optimize shelf-life?

Low permeability to atmospheric gases (A) Signup and view all the answers

What is a disadvantage of using organic solvents?

Environmental side effects (B) Signup and view all the answers

Which of the following is an example of an aqueous polymeric dispersion?

Aquacoat® cPD (B) Signup and view all the answers

What is one of the fundamental requirements of a tablet coating system?

Adequate mixing and agitation of the tablet bed (D) Signup and view all the answers

Which polymer is used for sustained release coating?

Methylmethacrylate (B) Signup and view all the answers

What is a benefit of using water as a solvent in modern techniques?

Lower environmental impact (D) Signup and view all the answers

Why are specialized dispersions of water insoluble polymers frequently used industrially?

To allow aqueous processing of water-insoluble polymers (C) Signup and view all the answers

What is the first step in the pan coating process?

Charge the pan with tablets and operate the drying air and exhaust (B) Signup and view all the answers

What is the purpose of controlling the air and temperature during the pan coating process?

To allow uniform spread of the coating solution before drying (C) Signup and view all the answers

Which of the following is NOT a process variable in the pan coating process?

Type of coating solution used (D) Signup and view all the answers

Which of the following is NOT an ideal characteristic of film-coated tablets?

Uniform tablet weight and size (A) Signup and view all the answers

What is the purpose of the fluidized-bed (air suspension) coating technique?

To keep the tablets in motion during the coating process (A) Signup and view all the answers

Which of the following is NOT one of the two basic systems used to apply a finely divided (atomized) spray onto tablets?

Ultrasonic atomization (A) Signup and view all the answers