Coagulopathy Workup Quiz

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Questions and Answers

Which laboratory tests should be completed immediately when coagulopathy is suspected?

  • Prothrombin time (PT), partial thromboplastin time (PTT), fibrinogen, platelet count (correct)
  • Complete blood count and liver function tests
  • Serum electrolytes and renal function tests
  • Hemoglobin and hematocrit

What initial treatment should be considered for a patient with decreased platelets or suspected thrombocytopathy?

  • Fresh frozen plasma
  • Administer DDAVP and 5-10 units of platelets (correct)
  • Provide vitamin K
  • Transfuse cryoprecipitate

In a patient with increased PT and PTT, but normal platelet counts and normal or increased fibrinogen levels, what is the appropriate treatment?

  • Platelet transfusion
  • Fibrin split products
  • Fresh frozen plasma (correct)
  • Cryoprecipitate

What combination of treatments is suggested for a patient with increased PT, increased PTT, low platelets, and decreased fibrinogen levels?

<p>Transfuse fibrin split products, cryoprecipitate, and platelets (A)</p> Signup and view all the answers

What should be ruled out in the initial evaluation of a patient with coagulopathy?

<p>Surgical hemostasis (B)</p> Signup and view all the answers

Flashcards

Coagulopathy workup

Evaluating bleeding disorders, especially during or after surgery, considering possible reasons (e.g., wound, IV sites, mucous membranes).

Initial coagulation tests

Immediately measuring PT, PTT, fibrinogen, and platelet count for coagulation status.

Low platelets

Indicates a decreased number of platelets, possibly requiring a platelet transfusion to stop potential hemorrhaging.

Increased PT and PTT

High PT (prothrombin time) and PTT (partial thromboplastin time), suggesting problems with clotting factors.

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Low platelets AND fibrinogen AND increased PT/PTT

Critical finding, suggesting severe clotting disorder issues and possible disseminated intravascular coagulation (DIC). Requires urgent treatment with a combination of therapies, likely including fibrin split products and cryoprecipitate.

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Study Notes

Coagulopathy Workup

  • Bleeding Type: Diffuse from wounds/IV sites, mucous membranes, or local (petechiae, ecchymoses)
  • Initial Evaluation: Rule out lack of surgical hemostasis, correct hypothermia, immediate PT, PTT, fibrinogen, and platelet count.

Decreased Platelets

  • Workup: Suspect thrombocytopathy
  • Treatment: Transfuse 5-10 units platelets, consider DDAVP.

Increased PT/PTT

  • Workup: Normal/Increased platelet counts, normal/increased fibrinogen
  • Treatment: Fresh frozen plasma

Increased PT/PTT (low platelets, decreased fibrinogen)

  • Workup: Low platelets, decreased fibrinogen
  • Treatment: Fibrin split products + cryoprecipitate + platelets

Disseminated Intravascular Coagulation (DIC)

  • Workup Suspect DIC. Evaluation is based on clinical scenario, injury type/location, fluid administered, and patient age/body temperature.

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