Podcast
Questions and Answers
What is the primary function of Antithrombin III in the coagulation cascade?
What is the primary function of Antithrombin III in the coagulation cascade?
How does Heparin exert its anticoagulant action?
How does Heparin exert its anticoagulant action?
Which natural anticoagulant is produced by the liver to inhibit factors V & VIII activity?
Which natural anticoagulant is produced by the liver to inhibit factors V & VIII activity?
Which autocrine-paracrine mediator promotes vasodilation and inhibits platelet activation?
Which autocrine-paracrine mediator promotes vasodilation and inhibits platelet activation?
Signup and view all the answers
What is the primary function of Tissue Factor Pathway Inhibitor (TFPI) in the coagulation cascade?
What is the primary function of Tissue Factor Pathway Inhibitor (TFPI) in the coagulation cascade?
Signup and view all the answers
Why is Protein S important in the regulation of blood clotting?
Why is Protein S important in the regulation of blood clotting?
Signup and view all the answers
What is the role of anticoagulant agents in preventing insult from developing thrombi or dislodging emboli?
What is the role of anticoagulant agents in preventing insult from developing thrombi or dislodging emboli?
Signup and view all the answers
Which type of anticoagulant agent directly binds to thrombin to inhibit its function?
Which type of anticoagulant agent directly binds to thrombin to inhibit its function?
Signup and view all the answers
What is the mechanism of action of Vitamin K inhibitors in the context of coagulation?
What is the mechanism of action of Vitamin K inhibitors in the context of coagulation?
Signup and view all the answers
In fibrinolysis, what is the role of tissue plasminogen activator (t-PA)?
In fibrinolysis, what is the role of tissue plasminogen activator (t-PA)?
Signup and view all the answers
Which of the following is NOT a target for digestion by the non-specific protease plasmin during fibrinolysis?
Which of the following is NOT a target for digestion by the non-specific protease plasmin during fibrinolysis?
Signup and view all the answers
What is the main outcome of fibrinolysis in terms of blood vessels blocked by a clot?
What is the main outcome of fibrinolysis in terms of blood vessels blocked by a clot?
Signup and view all the answers
Which of the following is a natural anticoagulant present in plasma?
Which of the following is a natural anticoagulant present in plasma?
Signup and view all the answers
Which enzyme is responsible for digesting and lysing fibrin clots?
Which enzyme is responsible for digesting and lysing fibrin clots?
Signup and view all the answers
Which of the following agents inhibits the action of vitamin K, thereby reducing the production of clotting factors?
Which of the following agents inhibits the action of vitamin K, thereby reducing the production of clotting factors?
Signup and view all the answers
Which of the following agents directly inhibits the action of thrombin?
Which of the following agents directly inhibits the action of thrombin?
Signup and view all the answers
Which of the following agents inhibits the action of factor Xa, thereby preventing thrombin generation?
Which of the following agents inhibits the action of factor Xa, thereby preventing thrombin generation?
Signup and view all the answers
Which of the following mediators secreted by endothelial cells has potential anticoagulant action?
Which of the following mediators secreted by endothelial cells has potential anticoagulant action?
Signup and view all the answers
