10 Questions
Transplanting the nucleus of an epithelial cell into an egg cell lacking genetic information leads to the formation of
a normally developing embryo.
Excess amounts of the amino acid tryptophan result in downregulation of the expression of the enzymes required for its synthesis due to
the repressor binding to the operator.
Mutations in which of the following elements would abrogate RNA polymerase’s ability to activate gene expression?
promoter
The figure below depicts which of the following mechanisms that cells use to maintain their identity through cell divisions?
positive feedback
Which of the following statements is correct regarding ATP driven pumps?
Eukaryotic cells contain a variety of ATP driven pumps including Na+/K+ ATPase, Ca++ ATPase and H+ ATPase.
MicroRNAs block the expression of a specific gene product by binding to the ___________ and inhibiting ___________.
mRNA; translation
A housekeeping gene is a gene whose cellular function is
important for processes found in all cell types.
In the cell, enhancer sequence functions are limited in their range of action by the formation of ___________ that hold specific genes and enhancers in close proximity.
loops
The regulatory control of a gene product after transcription is called
post-transcriptional control.
Noncoding RNAs include all of the following EXCEPT
mRNA.
Study Notes
Cloning and Gene Expression
- Transplanting the nucleus of an epithelial cell into an egg cell lacking genetic information leads to the formation of a cloned embryo.
- Excess amounts of the amino acid tryptophan result in downregulation of the expression of the enzymes required for its synthesis due to feedback inhibition.
RNA Polymerase and Gene Expression
- Mutations in the upstream element (enhancer) or the promoter region would abrogate RNA polymerase's ability to activate gene expression.
- The figure depicts the mechanism of chromatin-mediated inheritance, where cells use epigenetic markers to maintain their identity through cell divisions.
Cellular Transport
- ATP-driven pumps are correct in that they use energy from ATP hydrolysis to transport molecules across cell membranes against their concentration gradients.
MicroRNAs and Gene Regulation
- MicroRNAs block the expression of a specific gene product by binding to the 3' untranslated region (3'UTR) and inhibiting translation.
Housekeeping Genes
- A housekeeping gene is a gene whose cellular function is essential for the maintenance of basic cellular functions and is constantly expressed in all cells of an organism.
Enhancer Sequence Functions
- Enhancer sequence functions are limited in their range of action by the formation of chromatin loops that hold specific genes and enhancers in close proximity.
Post-Transcriptional Regulation
- The regulatory control of a gene product after transcription is called post-transcriptional regulation.
Noncoding RNAs
- Noncoding RNAs include all types of RNA molecules that are not translated into proteins, EXCEPT mRNA (messenger RNA).
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