Clinically Useful Competitive Inhibitors
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Questions and Answers

Which drug is used to treat gout by inhibiting xanthine oxidase?

  • Allopurinol (correct)
  • Alpha methyl dopa
  • fluorouracil
  • Neostigmine

What enzyme does penicillin inhibit, and what is its primary clinical use?

  • transpeptidase; bacteria (correct)
  • Thymidylate synthase; cancer
  • Dopa-decarboxylase; hypertension
  • DNA Polymerase; cancer

Which of the following drugs is specifically indicated for treating myasthenia gravis?

  • Allopurinol
  • fluorouracil
  • Neostigmine (correct)
  • Cytosine arabinoside

Fluorouracil inhibits which enzyme to aid in the treatment of cancer?

<p>Thymidylate synthase (D)</p> Signup and view all the answers

Which drug would be prescribed to a patient with hypertension by inhibiting dopa-decarboxylase?

<p>Alpha methyl dopa (A)</p> Signup and view all the answers

Flashcards

Competitive Inhibitor

A type of medication that prevents a specific enzyme from functioning properly.

Allopurinol

A drug used to treat gout by inhibiting xanthine oxidase, an enzyme involved in the breakdown of purines.

Penicillin

An antibiotic that inhibits transpeptidase, an enzyme crucial for bacterial cell wall synthesis.

Fluorouracil

A chemotherapy drug that inhibits thymidylate synthase, an enzyme necessary for DNA synthesis.

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Neostigmine

A drug used to treat myasthenia gravis by inhibiting acetylcholinesterase, an enzyme that breaks down acetylcholine.

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Study Notes

Clinically Useful Competitive Inhibitors

  • Allopurinol inhibits Xanthine Oxidase, used to treat gout.
  • Penicillin inhibits transpeptidase, used to treat bacterial infections.
  • Fluorouracil inhibits Thymidylate synthase, used to treat cancer.
  • Cytosine arabinoside inhibits DNA Polymerase, used to treat cancer.
  • Neostigmine inhibits Acetylcholinesterase, used to treat myasthenia gravis.
  • Alpha methyl dopa inhibits Dopa-decarboxylase, used to treat hypertension.

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Description

This quiz explores various clinically important competitive inhibitors and their corresponding uses in treatment. Each inhibitor targets a specific enzyme related to different medical conditions such as gout, bacterial infections, and cancer. Test your knowledge on these critical medications and their mechanisms.

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