Clinical Use of a Human Monoclonal Antibody

WellOak avatar
WellOak
·
·
Download

Start Quiz

Study Flashcards

18 Questions

What is the main route of administration for most drugs?

Oral

Which part of the GI tract is considered the most important endocrine system?

Small intestine

What is an example of a drug that can have direct effects on the GI system?

NSAIDs

What type of study might be conducted when there is a suspicion of a specific adverse reaction to a drug?

Cohort study

Which system can potentially interact with drugs in the GI tract?

Endocrine system

What is the function of gastric mucus in the GI tract?

Protects the stomach lining from acid damage

What is the clinical use of a human monoclonal antibody S.c. in patients with moderate-to-severe ulcerative colitis?

Induction and maintenance of remission in steroid-refractory or steroid-dependent UC

Which adverse effect is associated with the suppression of the TH1 inflammatory response by the human monoclonal antibody S.c.?

Reactivation of latent tuberculosis

What type of adverse infusion reaction is commonly seen with the administration of the human monoclonal antibody S.c.?

Fever, chills, pruritus, urticaria, or cardiopulmonary symptoms

What infection is a potential risk due to the use of the human monoclonal antibody S.c.?

Pneumonia

Which autoimmune response can develop as an adverse effect of the human monoclonal antibody S.c. treatment?

Antibodies against murine epitope of infliximab

What type of infection is commonly associated with the reactivation of latent tuberculosis in patients receiving the human monoclonal antibody S.c.?

Pneumocystosis

What adverse effect can be seen in long-term use of proton pump inhibitors (PPIs) related to calcium absorption?

Increased absorption of calcium leading to osteoporosis

Which of the following is a potential gastrointestinal (GI) adverse effect associated with prolonged inhibition of gastric secretion?

Decreased absorption of iron and vitamin B12

What is a possible neurological adverse effect associated with the use of proton pump inhibitors?

Lightheadedness and headaches

Which condition might be exacerbated in elderly or postmenopausal women due to prolonged use of proton pump inhibitors?

Osteoporosis

What potential skin-related adverse effect can be associated with the use of proton pump inhibitors?

Rash and itching

What interaction with other drugs can be expected when using proton pump inhibitors?

Reduced absorption for ampicillin and ketoconazole

Explore the clinical applications of a human monoclonal antibody, including induction and maintenance of remission in ulcerative colitis and Crohn's disease, treatment of anal fistula, and management of rheumatic inflammatory diseases such as rheumatoid arthritis. Learn about potential adverse effects and precautions.

Make Your Own Quizzes and Flashcards

Convert your notes into interactive study material.

Get started for free

More Quizzes Like This

Monoclonal Antibody Quiz
18 questions

Monoclonal Antibody Quiz

SimplestLouvreMuseum avatar
SimplestLouvreMuseum
Use Quizgecko on...
Browser
Browser