Podcast
Questions and Answers
What are the main routes of drug administration mentioned in the text?
What are the main routes of drug administration mentioned in the text?
- Oral, subcutaneous, nasal, topical
- Buccal, intrathecal, intraventricular, intra-articular
- Intramuscular, intravenous, intradermal, transdermal
- Oral, sublingual, rectal, inhalation (correct)
Which of the following factors influences drug absorption related to the absorbing surface?
Which of the following factors influences drug absorption related to the absorbing surface?
- Body weight
- Local blood flow (correct)
- Eye color
- Hair length
In which pH environment are acidic drugs more ionized?
In which pH environment are acidic drugs more ionized?
- Basic
- Neutral
- Acidic
- Alkaline (correct)
Which route of administration is generally the fastest for drug absorption?
Which route of administration is generally the fastest for drug absorption?
What type of drugs are more absorbed: ionized or nonionized?
What type of drugs are more absorbed: ionized or nonionized?
How does ischemia affect drug absorption?
How does ischemia affect drug absorption?
What is the formula for calculating the volume of distribution (Vd) of a drug?
What is the formula for calculating the volume of distribution (Vd) of a drug?
What does a total Vd of less than 5 L indicate about the drug's distribution in the body?
What does a total Vd of less than 5 L indicate about the drug's distribution in the body?
How can toxicity with acidic drugs be treated effectively?
How can toxicity with acidic drugs be treated effectively?
In what pH environment are basic drugs more likely to be trapped in breast milk?
In what pH environment are basic drugs more likely to be trapped in breast milk?
What does a total Vd greater than 41 L indicate about a drug's distribution in the body?
What does a total Vd greater than 41 L indicate about a drug's distribution in the body?
How can toxicity with basic drugs be effectively managed?
How can toxicity with basic drugs be effectively managed?
What is the purpose of phase I metabolism in drug metabolism?
What is the purpose of phase I metabolism in drug metabolism?
Which enzymes are responsible for catalyzing phase I metabolism?
Which enzymes are responsible for catalyzing phase I metabolism?
What is the role of glucuronyl transferase in phase II metabolism?
What is the role of glucuronyl transferase in phase II metabolism?
Define 'First-Pass' Metabolism in the context of drug administration.
Define 'First-Pass' Metabolism in the context of drug administration.
What is the bioavailability of a drug administered via the intravenous (IV) route?
What is the bioavailability of a drug administered via the intravenous (IV) route?
How does the bioavailability of atenolol compare to lidocaine, propranolol, and morphine?
How does the bioavailability of atenolol compare to lidocaine, propranolol, and morphine?
What is the formula to calculate the loading dose needed to attain a desired plasma concentration?
What is the formula to calculate the loading dose needed to attain a desired plasma concentration?
Why is it essential to consider drug clearance in pharmacokinetics?
Why is it essential to consider drug clearance in pharmacokinetics?
How does binding of drugs to plasma proteins impact drug efficacy?
How does binding of drugs to plasma proteins impact drug efficacy?
Which organ is the major site of drug metabolism in the body?
Which organ is the major site of drug metabolism in the body?
Give an example of a drug that undergoes metabolism to produce an active metabolite.
Give an example of a drug that undergoes metabolism to produce an active metabolite.
How can diseases affecting albumin levels impact drug therapy?
How can diseases affecting albumin levels impact drug therapy?
