Clinical Course of Chickenpox and Measles

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Questions and Answers

Match the Clinical Course Happening During Chickenpox with the appropriate description:

Incubation Period = 1 to 3 weeks Prodroma Period = 1 to 2 days before the rash appears until all vesicles have dried or crusted Infectious Period = May present as (shingles) Reactivation Period = Include symptoms such as N/V, headache, myalgia, loss of appetite, fever, and malaise

Which of the following are differences between Chickenpox and Measles?

  • Disseminated flat erythematous rash (correct)
  • Presence of Koplik's spots (correct)
  • Appears mainly on the trunk rather than the face and limbs (correct)
  • Tiny vesicles (small blisters) surrounded by reddened area
  • Involves Gl and respiratory symptoms
  • Associated with the following rash seqelae: anterior scalp line and behind the ears, then face, then trunk, then extremities

Identify which red flags for referral for chickenpox and measles are indicated by the following: (Select all that apply)

  • Erythematous rash or ulceration on the lower leg or ankles in an elderly person (correct)
  • Reduced urine output, lethargy, and reduced skin turgor
  • High temperature, pain, and redness around lesions (correct)
  • Requires immediate referral and notification (correct)

Which of the following is the MOST important lifestyle advice for people who have not yet contracted chickenpox or measles?

<p>Vaccination (C)</p> Signup and view all the answers

How would you BEST recommend the uptake of measles vaccine?

<p>Given at the age of 12 months, then 4 years old, subcutaneously (B)</p> Signup and view all the answers

Identify whether the following recommendations are appropriate or not: (Choose: Appropriate or Inappropriate)

<p>Ibuprofen in patients with chickenpox (A), Addition of 1% menthol to Topical Calamine Lotion for fever (B), Promethazine 25mg HS in a 3 y/o patient with chickenpox complaining of severe itchiness (D)</p> Signup and view all the answers

How can impetigo and cold sores be differentiated from each other? (Some Choices: Cold Sores, Non-bullous impetigo, Bullous Impetigo)

<p>Vesicles which rapidly break down to form golden crusts on face or extremities (A), Lesions may be seen on nerve innervations of the trigeminal nerve (B), Prodrome of itching, burning pain, or tingling symptoms hours to days prior to vesicle eruption (C)</p> Signup and view all the answers

Identify which red flags for referral for impetigo and cold sores are being indicated by the following: (Some choices: Widespread herpetiform eczema, Possible infection, May indicate sycosis harbo)

<p>Skin lesions accompanied by fever and malaise (A), Patient suffering from atopic eczema who has come into contact with an active cold sore (B), Papular rash, with or without vesicles and crusting, In the beard area of men (C)</p> Signup and view all the answers

Which of the following pharmacy product would you BEST recommend to a patient with history of cold sores?

<p>Face mask (D)</p> Signup and view all the answers

Which of the following would you BEST recommend to a patient with localized non-bullous impetigo?

<p>Antibiotics (B)</p> Signup and view all the answers

How should you counsel on the proper use of aciclovir cream for cold sores?

<p>Minimum day of administration must be at least 3 days (B), Should be used as soon as symptoms exist (C)</p> Signup and view all the answers

How can threadworm and roundworm be differentiated from each other? (Choice: Threadworm or Roundworm)

<p>May present as vague abdominal pain, N/V, diarrhea or bloody stools (B), Night-time perianal itching (D)</p> Signup and view all the answers

Identify which of the following is TRUE regarding use of Mebendazole in threadworms:

<p>Repeat dose 14 days later often recommended to ensure complete eradication (A), Two tablets of 100mg should be given as the initial dose (C), Strict personal hygiene is complementary to pharmacological treatment (D)</p> Signup and view all the answers

Flashcards

Chickenpox Incubation Period

Time between exposure and appearance of symptoms, usually 1-3 weeks.

Chickenpox Prodromal Period

Time before the rash appears, marked by common flu-like symptoms like fever, malaise, etc.

Chickenpox Infectious Period

Time when the patient can spread the virus, usually starts 1-2 days before rash and until all vesicles dry or crust.

Measles Incubation Period

Time between exposure and appearance of symptoms, often 10 days.

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Measles Prodromal Period

Includes fever, URTI symptoms and conjunctivitis (red eyes).

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Chickenpox Complications

Severe complications can arise, from pneumonia to encephalitis.

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Red Flags for Chickenpox/Measles Referral

Indications to seek immediate medical attention (e.g., bacterial superinfection, dehydration).

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Chickenpox vs Measles

Chickenpox: tiny blisters (vesicles), Measles: Koplik spots (white spots in the mouth).

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Lifestyle Advice (Chickenpox/Measles)

Vaccination is the most important preventive measure.

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Measles Vaccine Schedule

Typically given at 12 months, then again at 4 years old, subcutaneously.

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Appropriate Chickenpox Treatment

Use ibuprofen, avoid aspirin, monitor for severe itching and consider promethazine.

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Impetigo vs Cold Sores

Cold sores (HSV) have a prodrome of itching and burning, impetigo has golden crusts on the face/extremities.

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Red Flags for Impetigo/Cold Sores Referral

Indications of severe infection or complications requiring immediate medical attention (e.g., fever, malaise, skin ulceration).

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Cold Sore Treatment Recommendation

Use Aciclovir 5% cream as soon as symptoms appear, do not use for more than 7-10 days without consulting physician.

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Threadworm vs Roundworm

Threadworm: nighttime perianal itching, Roundworm: abdominal pain, diarrhea, cough.

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Mebendazole Use in Threadworms

Take as directed, often in two doses separated by two weeks, to ensure complete eradication.

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Acute Pain Treatment

Short-term treatment with NSAIDs or opiates, depending on severity.

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Types of Pain

Various types of pain (visceral, neuropathic, superficial/deep somatic) affecting different body parts.

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Oral Analgesic Recommendation

Ibuprofen is typically the first choice, but use naproxen for certain conditions as needed.

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Common Codeine Side Effect

Constipation is a well-known side effect.

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Topical Analgesic Choice

Capsaicin is a strong topical option for certain chronic pain conditions.

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Cluster Headache Symptom

Abrupt onset of pain around the eye.

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Meningitis Symptoms

Stiff neck and skin rash may be present along with a severe headache, especially in children.

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Migraine Treatment

Sumatriptan is a strong consideration for managing migraine.

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Smoking Cessation Consult steps

The consultation process follows a specific sequence; asking about the habits first.

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NRT Candidates

NRT (Nicotine Replacement Therapy) is suitable for most smokers, including light or heavy smokers, with exceptions.

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Oral NRT Considerations

Oral NRT carries potential risks and is not well-suited for everyone.

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Insomnia Types

Insomnia can be transient, chronic, and short term.

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Chickenpox Treatment: Ibuprofen

Ibuprofen is a suitable pain reliever for children and adults with chickenpox.

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Cold Sore Treatment: Aciclovir Cream

Aciclovir cream is usually the recommended treatment for cold sores. It is most effective if started as soon as symptoms appear. It should be be used for no more than 7-10 days without consulting a physician.

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Types of Pain: Visceral Pain

Visceral pain originates from internal organs or cavities. It's usually described as deep, throbbing, or cramping.

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Types of Pain: Neuropathic Pain

Neuropathic pain is caused by damage or dysfunction of the nerves. It is often described as burning, tingling, or shooting pain.

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Types of Pain: Superficial Somatic Pain

Superficial somatic pain comes from skin, muscles, or connective tissues. It's typically sharp or localized.

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Types of Pain: Deep Somatic Pain

Deep somatic pain originates from deep tissues like bones, tendons, or ligaments. It's often described as dull or aching.

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Oral Analgesic Recommendation: Ibuprofen

Ibuprofen is often the first-line analgesic for a variety of conditions, including back pain, tension headaches, and dysmenorrhea (menstrual cramps). It is important to consult a physician about the appropriate dosage and duration of use.

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Codeine Common Side Effect

Constipation is a common side effect of codeine-containing analgesics. This is due to codeine's action on the gastrointestinal tract.

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Topical Analgesic Recommendation: Capsaicin

Capsaicin, the active ingredient in chili peppers, is a strong topical analgesic used for chronic pain conditions, such as osteoarthritis and nerve pain. It works by depleting substance P, a neurotransmitter involved pain signaling.

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Migraine Treatment: Sumatriptan

Sumatriptan is a medication used to treat acute migraine attacks. It works by narrowing blood vessels in the brain, which reduces pain and other migraine symptoms.

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Smoking Cessation Consult: Asking About Tobacco Use

The first step in a smoking cessation consultation is to ask the patient about their tobacco use history and current habits.

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Insomnia Types: Transient Insomnia

Transient insomnia is short-term sleep disturbance, lasting only a few days or weeks. It is often caused by stress, travel, or a change in environment.

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Insomnia Types: Chronic Insomnia

Chronic insomnia is persistent sleep disturbance that lasts three months or longer. It can be due to underlying medical conditions, mental health issues, or unhealthy sleep habits.

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First-line Therapy for Insomnia: Cognitive Behavioral Therapy for Insomnia (CBTI)

CBTI is a highly effective, non-drug treatment for insomnia. It helps people identify and change unhealthy sleep habits to improve sleep quality.

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Medicine-induced N/V: Digoxin

Digoxin, a medication used to treat heart failure, is a common cause of medicine-induced nausea and vomiting.

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Domperidone Timing

Domperidone, a medication used to relieve nausea and vomiting, should be taken before meals to help prevent or reduce these symptoms.

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Motion Sickness Prevention: Accupressure Point

Acupressure can be used to help prevent motion sickness. The P6 point is located on the inner side of the wrist, about two fingers' width below the wrist crease. Apply pressure to this point with a wristband or your fingers to help reduce nausea and vomiting.

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Antihistamine for Motion Sickness: Meclizine

Meclizine is an antihistamine that can be used to prevent or reduce motion sickness. It typically has longer-lasting effects compared to other antihistamines and is often preferred for longer journeys.

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Motion Sickness: When to Take Antihistamines

Antihistamines for motion sickness should be taken before exposure to motion, such as a plane or car trip, to be most effective in preventing symptoms.

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Acute Low Back Pain Red Flags: Cauda Equina Syndrome

Cauda equina syndrome is a serious condition that requires immediate medical attention. It is characterized by severe low back pain, numbness, and bowel or bladder dysfunction. This suggests compression of the nerve roots in the lower spinal canal.

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Lifestyle Advice for Acute Low Back Pain: Exercise Programs

Exercise programs, tailored to the individual's needs and pain levels, can help strengthen muscles, improve flexibility, and reduce pain in acute low back pain.

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Adjuvant Therapy for Osteoarthritis: Glucosamine

Glucosamine is a naturally occurring substance found in cartilage. It is often used as an adjuvant therapy for osteoarthritis, as it may help protect cartilage and reduce pain.

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Soft Tissue Injury: Achilles Tendon Injuries

Achilles tendon injuries involve the large tendon at the back of the ankle. Signs include pain behind the heel, tenderness, swelling, and difficulty with walking. The severity can range from small tears to complete ruptures.

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Soft Tissue Injury: Rotator Cuff Syndrome

Rotator cuff syndrome involves the muscles and tendons that surround the shoulder joint. It is often caused by overuse, injury, or degeneration. Symptoms include pain, weakness, and limited range of motion of the shoulder.

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RICE Therapy: Compression

Compression helps to reduce swelling and promote blood flow to the injured area. It can be achieved using a bandage or compression garment.

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WHO BMI for Asians: Normal

A BMI of 23.5 for a Filipino patient falls within the normal range according to the WHO BMI classification for Asians.

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Weight Loss Recommendation: Diet and Exercise

For obese patients, it is crucial to combine healthy dietary changes with regular exercise to achieve sustainable weight loss. This approach is often the most effective and long-term solution.

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Orlistat: Hypocaloric Diet

Orlistat is a medication that blocks the absorption of fat in the diet. It is most effective when used in combination with a low-fat, hypocaloric diet.

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Eye Examination: Visual Acuity

To assess visual acuity, ask the patient to read small print from a distance. This test determines how clearly the patient can see details at a specific distance.

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Conjunctivitis: Bacterial

Bacterial conjunctivitis, also known as pink eye, is characterized by a purulent (thick, yellow) discharge from the eye. It is highly contagious and can spread quickly.

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Conjunctivitis: Allergic

Allergic conjunctivitis is caused by an allergic reaction to substances like pollen, dust mites, or pet dander. It presents with itching of the eye, redness that is generally diffused (spread out), and watery discharge. It can also be associated with a family history of atopy (tendency to develop allergies).

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Eye Referral: True Eye Pain

If a patient experiences true eye pain, it is important to refer them to a physician. It is crucial to rule out serious conditions such as scleritis, keratitis, or acute glaucoma.

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Conjunctivitis: Lifestyle Advice: Avoid Contact Lenses

It is important to avoid wearing contact lenses until the symptoms of conjunctivitis have resolved to prevent further irritation and possible worsening of the infection.

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Bacterial Conjunctivitis Recommendation: Chloramphenicol Eye Drops

Chloramphenicol eye drops are a common and effective treatment for bacterial conjunctivitis. They help reduce bacterial growth and relieve associated symptoms.

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Allergic Conjunctivitis Prophylaxis: Intraocular Sodium Cromoglycate

Intraocular sodium cromoglycate eye drops are a helpful prophylactic measure for allergic conjunctivitis. They help to lessen the allergic reaction and reduce the symptoms.

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Dry Eyes: Medicine-Induced Dry Eyes: Beta-blockers

Beta-blockers, a class of medication commonly used to treat hypertension and other cardiovascular conditions, can sometimes lead to dry eyes as a side effect.

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Artificial Tears: Patient Preference

The choice of artificial tears should be tailored to the patient's individual preferences. This includes considerations such as the type of solution, the drop size, the viscosity, and the preservation system.

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Artificial Tears Formulation: Hypromellose 2% Eye Drops

Hypromellose 2% eye drops are a common type of artificial tears. They provide lubrication and moisture, which can help to alleviate symptoms of dry eyes. They are also generally well-tolerated.

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Eye Referral: Orbital Cellulitis

Orbital cellulitis is a serious infection of the tissue surrounding the eye. It is characterized by swelling of the eyelids, redness, pain, fever, and sometimes difficulty moving the eye. It requires prompt medical attention.

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Blepharitis or Stye Treatment: Conservative Treatment

Blepharitis and styes, both involving inflammation of the eyelid, are often treated with conservative measures, which include warm compresses and good lid hygiene practices to help reduce inflammation and promote healing.

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Good Lid Hygiene: Avoid Squeezing Stye

It is important to avoid squeezing or picking at a stye. Squeezing can trap infected material within the eyelid, increasing the risk of further inflammation and infection.

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Ear Problem: Inner Ear

Tinnitus (ringing in the ears) and deafness (hearing loss) are typically associated with problems in the inner ear.

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Earache: Oral Analgesic Recommendation

For most adults, earache is a self-limiting condition that can be managed with over-the-counter oral analgesics, such as paracetamol or ibuprofen, for a maximum of two days. If the symptoms persist or worsen, a physician should be consulted.

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Ear Referral: Possible Middle Ear Infection

In children, especially young children, earache accompanied by fever and general malaise is often a sign of a middle ear infection (otitis media). This requires referral to a physician for further evaluation and treatment.

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Cerumenolytics: Hydrogen Peroxide

Hydrogen peroxide can be used as a cerumenolytic (earwax softener) to help remove excess earwax. However, it should be used with caution and only as directed by a healthcare professional. Applying a cotton wool plug after instillation is not recommended.

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Otitis Externa: Lifestyle Advice: Avoid Cotton Buds

Using cotton buds to clean the ear canal should be avoided as it can push earwax further in and increase the risk of otitis externa (inflammation of the ear canal).

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Teething Infants: Cool Washcloth

Teething infants can experience discomfort, swelling, and pain in their gums. A cool washcloth is a safe and effective method to help reduce the discomfort.

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Mouth Ulcer: Trauma-induced Ulcer

Trauma-induced mouth ulcers are caused by injury to the oral mucosa (lining of the mouth). These ulcers are often painful and may be irregular in shape.

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Mouth Ulcer: MAU (Minor Aphthous Ulcer)

Minor aphthous ulcers are small, shallow ulcers that usually occur inside the mouth, often on the soft palate or inside the cheeks. They are painful and typically last about 7-10 days.

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MAU Treatment: Benzydamine

Benzydamine is a medication used to treat minor aphthous ulcers. It is available as a mouthwash or gel and has analgesic and anti-inflammatory properties.

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Oral Thrush: Medicine-Induced

Certain medications, like inhaled corticosteroids used for asthma, immunosuppressants, and antibiotics, can increase the risk of developing oral thrush (candidiasis) by disrupting the natural balance of fungi in the mouth.

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Miconazole for Oral Thrush: Continue Treatment After Symptoms Clear

To prevent relapse or reinfection with oral thrush, treatment with miconazole should be continued for at least two days after the symptoms have cleared to ensure that the infection is completely eradicated.

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Gingivitis Prevention: Regular Flossing

Regular and proper flossing, along with brushing, is essential for removing plaque and food debris, which can accumulate between teeth and contribute to gingivitis (gum inflammation).

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Study Notes

Clinical Course During Chickenpox

  • Incubation period: 1 to 2 days before rash to when all vesicles dry
  • Prodromal period: 1 to 3 weeks before rash, includes symptoms like nausea, headache, myalgia, loss of appetite, fever, and malaise
  • Infectious period: lasts until all vesicles dry or crust
  • Reactivation period: not applicable to chickenpox

Clinical Course During Measles

  • Incubation period: 10 days
  • Prodromal period: may present as fever, URTI (upper respiratory tract infection) catarrhal phase symptoms, conjunctivitis, and Koplik's spots.
  • Infectious period: highest during late prodromal period
  • Complications: may involve pneumonia, encephalitis, and otitis media

Chickenpox vs. Measles

  • Chickenpox:

    • Tiny vesicles (blisters)
    • Rash on trunk and limbs
    • Sequelae of rashes in specific order
    • Involves Gl and respiratory symptoms
  • Measles:

    • Koplik's spots
    • Disseminated rash
    • Rash on face, then trunk, then extremities

Red Flags for Referral (Chickenpox/Measles)

  • High temperature, pain, and redness around lesions
  • Reduced urine output, lethargy, and reduced skin turgor
  • Erythematous rash or ulceration on lower leg/ankles (in elderly)
  • Bacterial superinfection, possible measles, dehydration, or cellulitis

Lifestyle Advice (Chickenpox/Measles)

  • Vaccination
  • Exclusion from school/nursery
  • Smooth cotton fabrics to minimize skin irritation
  • Adequate fluid intake

Measles Vaccine

  • Recommended age: 12 months and then 4 years old
  • Administration method: subcutaneously

Other Observations

  • Ibuprofen is appropriate for Chickenpox

  • Aspirin is not appropriate for adults with Chickenpox

  • Topical Calamine Lotion with menthol for fever is recommended

  • Impetigo and cold sores can be differentiated by characteristic vesicles.

  • Recommendations for impetigo and cold sores vary.

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