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Questions and Answers
Which methodology is most widely used to detect catecholamines and their metabolites in plasma and urine?
Which methodology is most widely used to detect catecholamines and their metabolites in plasma and urine?
- Radioimmunoassay
- High-Performance Liquid Chromatography (HPLC) (correct)
- Enzyme-linked immunosorbent assay (ELISA)
- Western blotting
What is the enzyme specifically found exclusively in both diseased and benign prostate glands?
What is the enzyme specifically found exclusively in both diseased and benign prostate glands?
- Alkaline phosphatase
- Prostate specific antigen (PSA) (correct)
- Lactate dehydrogenase
- Aspartate aminotransferase
Which tumor marker is re-expressed in certain types of tumors and is elevated in patients with hepatocellular carcinoma and germ cell tumors?
Which tumor marker is re-expressed in certain types of tumors and is elevated in patients with hepatocellular carcinoma and germ cell tumors?
- Cancer Antigen 125 (CA-125)
- Alpha-fetoprotein (AFP) (correct)
- Prostate Specific Antigen (PSA)
- Beta-human chorionic gonadotropin (β-hCG)
What is the main limitation associated with the detection of elevated circulating enzymes to identify a specific tumor or site of tumor?
What is the main limitation associated with the detection of elevated circulating enzymes to identify a specific tumor or site of tumor?
In immunohistochemistry, specific antibodies in solution are incubated with tissue sections to detect the presence or absence of __________ using secondary antibodies.
In immunohistochemistry, specific antibodies in solution are incubated with tissue sections to detect the presence or absence of __________ using secondary antibodies.
Which tumor marker is NOT completely specific for hepatocellular carcinoma (HCC)?
Which tumor marker is NOT completely specific for hepatocellular carcinoma (HCC)?
Which type of tumor markers are best used for monitoring the treatment of tumors that secrete specific carbohydrates or cancer antigens?
Which type of tumor markers are best used for monitoring the treatment of tumors that secrete specific carbohydrates or cancer antigens?
What type of tumor markers are widely used as specific markers of secreting tumors such as neuroblastomas, pituitary, and adrenal adenomas?
What type of tumor markers are widely used as specific markers of secreting tumors such as neuroblastomas, pituitary, and adrenal adenomas?
Which method is valuable in diagnosing patients with breast, ovarian, or colon cancer by identifying germline mutations in individuals with a family history of these diseases?
Which method is valuable in diagnosing patients with breast, ovarian, or colon cancer by identifying germline mutations in individuals with a family history of these diseases?
Which tumor marker type generally increases with tumor progression and reaches its highest levels when tumors metastasize?
Which tumor marker type generally increases with tumor progression and reaches its highest levels when tumors metastasize?
What is the main limitation in using tumor markers for screening asymptomatic populations according to the text?
What is the main limitation in using tumor markers for screening asymptomatic populations according to the text?
In which type of diagnostic method is the Hook Effect sometimes encountered as an issue based on the provided text?
In which type of diagnostic method is the Hook Effect sometimes encountered as an issue based on the provided text?
Which type of marker is beta2-microglobulin considered to be?
Which type of marker is beta2-microglobulin considered to be?
What is the main characteristic of immunoglobulins in the context of tumor markers?
What is the main characteristic of immunoglobulins in the context of tumor markers?
Which statement accurately describes tumor markers according to the text?
Which statement accurately describes tumor markers according to the text?
Which statement best describes oncofetal antigens based on the information provided?
Which statement best describes oncofetal antigens based on the information provided?
Which technique is frequently utilized for the detection of tumor markers like cancer antigen 125?
Which technique is frequently utilized for the detection of tumor markers like cancer antigen 125?
What is a key characteristic of frequently ordered tumor markers?
What is a key characteristic of frequently ordered tumor markers?
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