Clinical Chemistry: Kidney Function Tests

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16 Questions

What is the main function of the kidneys?

Filtering minerals from the blood

In the event of kidney failure, what complication can arise due to fluid retention?

Edema or swelling of the extremities

Where are the kidneys normally located in the human body?

Between the 11th thoracic and 3rd lumbar vertebrae

What is the functional unit of the kidney called?

Nephron

From which blood vessels do the kidneys receive blood?

Renal arteries

What is the purpose of the glomerulus in the nephron?

To filter blood and form filtrate

What is the primary purpose of the glomerulus?

Filtration of water, electrolytes, and nutrients

What factors does the filtration in the glomerulus depend on?

Size and charge of the particles

Which test measures the end product of protein catabolism?

Blood urea nitrogen

What does a rise in the level of serum urea generally indicate?

Reduced glomerular function

Which function is NOT associated with the kidney?

Synthesis of vitamin C

What is responsible for reabsorption of most water, electrolytes, and nutrients in the kidney?

Tubular system

What type of diet may increase the blood urea level?

High protein diet

What is the normal range for serum urea level?

$20-45$ mg/dl

What does a rise in the level of serum urea indicate when it comes to glomerular function?

$<50 ext{%}$ reduction in glomerular function

What does a qualitative examination of urine provide clues to?

The location of the lesion in the renal system

Study Notes

Kidney Function

  • The main function of the kidneys is to filter waste and excess fluids from the blood.

Location and Structure

  • The kidneys are normally located in the human body in the upper abdominal cavity.
  • The functional unit of the kidney is called a nephron.
  • The kidneys receive blood from the renal arteries.

Glomerulus Function

  • The glomerulus is a cluster of capillaries in the nephron responsible for filtration.
  • The primary purpose of the glomerulus is to filter the blood and remove waste products.
  • Filtration in the glomerulus depends on factors such as blood pressure, permeability of the glomerular capillaries, and the concentration of proteins in the blood.

Kidney Functions and Tests

  • A rise in the level of serum urea generally indicates kidney dysfunction or failure.
  • The blood urea nitrogen (BUN) test measures the end product of protein catabolism.
  • A qualitative examination of urine provides clues to kidney function and potential diseases.

Kidney Function and Diet

  • A high-protein diet may increase the blood urea level.
  • The normal range for serum urea level varies, but a rise in serum urea level indicates impaired glomerular function.

Non-Kidney Functions

  • The kidney is not responsible for storing bile.

Learn about the importance of kidney function tests in clinical chemistry and the role of kidneys in filtering minerals, maintaining fluid balance, excreting waste products, and regulating blood volume. Understand the significance of kidney function for overall health.

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