Cleft Lip and Cleft Palate Quiz
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Questions and Answers

Which duct forms a remnant called Gartner duct in females?

  • Mesonephric (Wolffian) Duct
  • Paramesonephric (Müllerian) Duct (correct)
  • Neither duct forms Gartner duct
  • Both ducts form Gartner duct

What is the main characteristic of Mayer-Rokitansky-Küster-Hauser Syndrome?

  • Presence of functional ovaries
  • Presence of an absent uterus (correct)
  • Presence of normal female external genitalia
  • Presence of a blind vaginal pouch

Which duct develops into internal male genitalia in XY individuals?

  • Both ducts develop into internal male genitalia
  • Mesonephric (Wolffian) Duct (correct)
  • Paramesonephric (Müllerian) Duct
  • Neither duct develops into internal male genitalia

What causes the regression of the Paramesonephric (Müllerian) Duct in XY individuals?

<p>The action of Müllerian inhibitory factor (MIF) (A)</p> Signup and view all the answers

What is the main role of Leydig cells in the testes?

<p>To produce testosterone (A)</p> Signup and view all the answers

What is the result of 5α-reductase deficiency?

<p>Development of male internal genitalia and atypical external genitalia (B)</p> Signup and view all the answers

Which of the following is part of the male external genitalia?

<p>Penis (B)</p> Signup and view all the answers

Which of the following is part of the female internal genitalia?

<p>Fallopian tubes (B)</p> Signup and view all the answers

What can uterine (Müllerian duct) anomalies cause?

<p>Fertility issues and complicated pregnancies (B)</p> Signup and view all the answers

What is the common treatment for septate uterus?

<p>Septoplasty (A)</p> Signup and view all the answers

Which process is involved in the formation of cleft lip?

<p>Intermaxillary segment (B)</p> Signup and view all the answers

Which process is involved in the formation of cleft palate?

<p>Palatine shelves (2° palate) (D)</p> Signup and view all the answers

Which duct develops into female internal structures?

<p>Müllerian Duct (Paramesonephric Duct) (A)</p> Signup and view all the answers

Which gene on the Y chromosome leads to testes development?

<p>SRY gene (C)</p> Signup and view all the answers

Which cells secrete Müllerian inhibitory factor (MIF)?

<p>Sertoli cells (B)</p> Signup and view all the answers

Which cells secrete androgens that stimulate the development of mesonephric ducts?

<p>Leydig cells (A)</p> Signup and view all the answers

Which structures develop as a result of female default development?

<p>Metanephric kidney, Ureter, Uterus, Vagina, Oviduct, and Urinary bladder (D)</p> Signup and view all the answers

Which structures develop as a result of male development?

<p>Testis, Epididymis, Vas deferens, and Urinary bladder (C)</p> Signup and view all the answers

What does the Müllerian Duct regress into in males?

<p>Appendix testis (D)</p> Signup and view all the answers

Which duct develops into male internal structures (except prostate)?

<p>Wolffian Duct (Mesonephric Duct) (D)</p> Signup and view all the answers

Which structure is involved in the formation of cleft lip?

<p>Frontonasal process (D)</p> Signup and view all the answers

Which structure is involved in the formation of cleft palate?

<p>Palatine shelves (B)</p> Signup and view all the answers

Which structure develops into the fallopian tubes in females?

<p>Müllerian Duct (D)</p> Signup and view all the answers

Which structure develops into the seminal vesicles in males?

<p>Wolffian Duct (C)</p> Signup and view all the answers

What is the role of Sertoli cells in male development?

<p>Suppress development of paramesonephric ducts (D)</p> Signup and view all the answers

What is the main role of Leydig cells in the testes?

<p>Produce androgens (C)</p> Signup and view all the answers

Which structure develops as a result of female default development?

<p>Uterus (D)</p> Signup and view all the answers

Which structure develops as a result of male development?

<p>Epididymis (C)</p> Signup and view all the answers

What does the Müllerian Duct regress into in males?

<p>Appendix testis (C)</p> Signup and view all the answers

Which structure forms the 2° palate in the development of cleft palate?

<p>Palatine shelves (D)</p> Signup and view all the answers

Which of the following is a characteristic of Müllerian Agenesis (Mayer-Rokitansky-Küster-Hauser Syndrome)?

<p>Presence of a blind vaginal pouch (A)</p> Signup and view all the answers

Which duct develops into internal female genitalia in XX individuals?

<p>Paramesonephric (Müllerian) Duct (C)</p> Signup and view all the answers

Which cells in the testes secrete Müllerian inhibitory factor (MIF)?

<p>Sertoli cells (A)</p> Signup and view all the answers

What is the result of 5α-reductase deficiency?

<p>Male internal genitalia development (A)</p> Signup and view all the answers

Which of the following is part of the male external genitalia?

<p>Prostate (B)</p> Signup and view all the answers

Which duct develops into male internal structures (except prostate) in XY individuals?

<p>Mesonephric (Wolffian) Duct (C)</p> Signup and view all the answers

Which duct forms a remnant called Gartner duct in females?

<p>Mesonephric (Wolffian) Duct (A)</p> Signup and view all the answers

Which cells secrete androgens that stimulate the development of mesonephric ducts?

<p>Leydig cells (C)</p> Signup and view all the answers

What is the main characteristic of Uterine (Müllerian duct) anomalies?

<p>Increased risk of complicated pregnancies (C)</p> Signup and view all the answers

What is the common treatment for septate uterus?

<p>Septoplasty (A)</p> Signup and view all the answers

Flashcards

Paramesonephric Duct

Develops into female internal reproductive structures in XX individuals, such as the oviducts and uterus.

Müllerian Duct

Another name for the paramesonephric duct.

Mesonephric Duct

Develops into male internal reproductive structures in XY individuals, except the prostate.

Wolffian Duct

Another name for mesonephric duct.

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Gartner Duct

Remnant of the mesonephric duct found in females.

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SRY gene

Gene on the Y chromosome that triggers male development.

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Leydig cells

Cells in the testes that produce androgens (e.g., testosterone).

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Sertoli cells

Cells in the testes that produce Müllerian inhibitory factor (MIF).

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Müllerian inhibitory factor (MIF)

A factor that causes regression of the paramesonephric duct in males.

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5α-reductase deficiency

Condition causing male internal structure development but atypical external genitalia.

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Mayer-Rokitansky-Küster-Hauser Syndrome

A condition where the uterus is absent.

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Penis

Part of the male external genitalia.

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Fallopian tubes

Part of the female internal genitalia.

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Uterine anomalies

Abnormal development of the uterus.

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Septoplasty

Procedure to correct a septate uterus.

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Cleft lip

Abnormal facial development where upper lip does not fuse properly.

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Cleft palate

Abnormal development where the palate does not join completely, separating mouth and nasal parts.

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Intermaxillary segment

A part of the face that helps form the upper lip.

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Palatine shelves

Structures that fuse to form the roof of the mouth.

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Appendix testis

Remnant of the Müllerian duct in males.

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Metanephric kidney

Develops as a result of female default development.

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Frontonasal process

Facial structure involved in cleft lip.

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Prostate

Not formed from the mesonephric duct.

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Fertility issues

Problems with conceiving a baby.

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Study Notes

Development of Genitalia

  • Wolffian duct develops into internal male genitalia in XY individuals
  • Müllerian duct develops into internal female genitalia in XX individuals
  • Mesonephric duct develops into male internal structures (except prostate) in XY individuals
  • Paramesonephric duct develops into female internal structures

Regression of Ducts

  • Müllerian duct regresses into a remnant called Gartner duct in females
  • Paramesonephric duct regresses in XY individuals due to the action of Müllerian inhibitory factor (MIF)

Hormones and Factors

  • Leydig cells secrete androgens that stimulate the development of mesonephric ducts
  • Sertoli cells secrete Müllerian inhibitory factor (MIF)
  • 5α-reductase deficiency results in undersized genitalia and prostate gland

Syndromes and Anomalies

  • Mayer-Rokitansky-Küster-Hauser Syndrome: main characteristic is the absence of the uterus and vagina
  • Uterine (Müllerian duct) anomalies: can cause infertility, recurrent miscarriage, and premature birth
  • Common treatment for septate uterus is surgery to remove the septum

Formation of Cleft Lip and Palate

  • Frontonasal prominence is involved in the formation of cleft lip
  • Palatal shelves are involved in the formation of cleft palate
  • The secondary palate forms from the palatal shelves

Development of External Genitalia

  • Genital tubercle is part of the male external genitalia
  • Ovary is part of the female internal genitalia

Genes and Development

  • SRY gene on the Y chromosome leads to testes development
  • Default development in the absence of the SRY gene leads to female internal genitalia
  • In the presence of the SRY gene, male development occurs

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Description

Test your knowledge on cleft lip and cleft palate with this quiz! Learn about the processes involved in their formation and the structures affected. Discover the connection between cleft lip and cleft palate.

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