Clear Cell Sarcoma and Malignant Melanocytic Sarcoma Quiz

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Which bone tumor is characterized by large lesions in the interior of diaphysis or metaphysis, with bone enlargement, focal periosteal reactions, and extension into soft tissue?

Epithelioid sarcoma

Fibrosarcoma (correct)

Aggressive melanocytic sarcoma

Clear cell sarcoma

What is a notable feature of calcification in tumors of the foot/ankle?

Bubble radiolucency (correct)

Soft tissue mass

Onion skin appearance

Moth-eaten appearance

Which malignant bone tumor typically has neuroectodermal cell origin and manifests as a mottled, moth-eaten destructive lesion with an 'onion skin' appearance?

Epithelioid sarcoma

Calcaneus Fibrosarcoma

Clear cell sarcoma (correct)

Aggressive melanocytic sarcoma

In which age group is aggressive melanocytic sarcoma most commonly seen?

>20 years Signup and view all the answers

Which bone tumor is associated with a spindle cell stroma producing immature bone, and can have a 40% 5-year survival rate?

Epithelioid sarcoma Signup and view all the answers

Which bone tumor has a 20% 5-year survival rate due to lung metastasis, and is more common in individuals over 20 years old?

Clear cell sarcoma Signup and view all the answers

Which tumor is characterized by clear cytoplasm and prominent nucleoli?

Clear cell sarcoma Signup and view all the answers

Which tumor is associated with a 'fish scale' pattern of calcification on X-ray?

Epithelioid sarcoma Signup and view all the answers

Which tumor is characterized by a 'storiform' growth pattern and marked nuclear pleomorphism?

Fibrosarcoma Signup and view all the answers

Which tumor is known for its aggressive behavior and high mitotic rate?

Epithelioid sarcoma Signup and view all the answers

Which tumor type often presents with aggressive features such as ulceration and bleeding?

Fibrosarcoma Signup and view all the answers

Which tumor is likely to show a 'salt and pepper' appearance on histological examination?

Aggressive melanocytic sarcoma Signup and view all the answers

Which soft tissue tumor is more common in males, affects individuals in their 30s-40s, and is typically found in deep-seated regions of the extremities?

Clear cell sarcoma Signup and view all the answers

Which imaging modality may show a benign appearance with homogenous T1 and heterogenous T2 findings in melanocytic tumors?

MRI Signup and view all the answers

Which soft tissue tumor typically presents with a 'Herring bone pattern' consisting of interlacing sheets of spindle-like fibroblasts?

Epithelioid sarcoma Signup and view all the answers

In which age group is Epithelioid sarcoma most commonly found?

10-25 years old Signup and view all the answers

Which benign tumor, affecting the knee and hip, typically presents as asymptomatic but can cause pain relieved by ASPIRIN?

Osteoid osteoma Signup and view all the answers

'Notable thing' found in the X-ray of which malignant tumor includes calcification and erosion of adjacent bone?

Epithelioid sarcoma Signup and view all the answers

Which benign lesion is characterized by anechoic appearance on ultrasound and may be septate?

Ganglion cyst Signup and view all the answers

In which age group is neuroblastoma most commonly seen?

Under 5 years old Signup and view all the answers

Which benign tumor is more common in individuals aged 50-70 and affects the synovial lining of fingers and toes?

Mucoid cyst Signup and view all the answers

Which benign lesion is likely to show transillumination with skin and is usually painless unless it compresses a nerve?

Lipoma Signup and view all the answers

What is the most common primary malignant tumor in the body, characterized by plasma cells with lytic lesions and monoclonal gammopathy?

Multiple myeloma Signup and view all the answers

Which benign lesion typically occurs in individuals aged 40-60 and can be found anywhere fat persists in the body?

Lipoma Signup and view all the answers

What is the characteristic MRI finding associated with hemangiomas in children?

Bag of worms appearance Signup and view all the answers

Which tumor type is characterized by a blue-red blanchable papule and is commonly found under the nail bed?

Glomus tumor Signup and view all the answers

What is the most common benign peripheral nerve sheath tumor?

Schwannoma Signup and view all the answers

Which soft tissue tumor typically affects individuals in the age range of 15-35 years and is found in periarticular regions like tendon sheaths and joint capsules?

Synovial sarcoma Signup and view all the answers

What is the characteristic feature of synovial sarcomas on X-ray imaging?

Calcifications eccentrically or peripherally Signup and view all the answers

Which tumor is characterized by cold sensitivity, known as Love's test, and is commonly found in the finger or toe nail beds?

Glomus tumor Signup and view all the answers

Which bone tumor is characterized by a piece of bone that breaks off and deposits on the gravity-dependent edge of the tumor?

Solitary (unicameral) bone cyst Signup and view all the answers

Which benign tumor has an oval, radiolucent appearance with a border of sclerosis resembling osteomyelitis?

Eosinophilic granuloma Signup and view all the answers

Which malignant bone tumor may mimic osteomyelitis and present with pain, swelling, warmth, fever, and increased ESR?

Ewing sarcoma Signup and view all the answers

Which malignant bone tumor is associated with periosteal reaction leading to an 'onion skin' appearance and a soft tissue mass?

Ewing sarcoma Signup and view all the answers

Which malignant bone tumor has a matrix in the periosteum and develops in places of active growth like long bones of the knee?

Osteogenic sarcoma Signup and view all the answers

Which malignant bone tumor is the most common malignant bone tumor of the foot/ankle with bubble radiolucency, calcifications, and calcifications?

Chondrosarcoma Signup and view all the answers

Which tumor type presents with a neural phenotype, identical chromosome translocation, and is classified as an UNDIFFERENTIATED small round blue tumor?

Primitive neuroectodermal tumor (PNET) Signup and view all the answers

Which benign bone tumor may appear as an asymptomatic incidental finding on x-ray, typically affecting the metaphysis of the distal femur and proximal tibia, and is known for having scalloped margins?

Benign fibrous cortical defect Signup and view all the answers

In which type of tumor would one likely observe Homer Wright rosettes and a neural phenotype?

Primitive neuroectodermal tumor (PNET) Signup and view all the answers

Which benign bone tumor is characterized by radiolucency in the epiphysis of long bones such as the distal radius and knee, and is often associated with arthritis-like symptoms?

Giant cell tumor Signup and view all the answers

Which bone tumor, benign in most cases, can present with curvilinear spicules of immature woven bone surrounded by fibroblastic proliferation, and is typically found anywhere in the long bones, jaw, or skull?

Fibrous dysplasia Signup and view all the answers

Which soft tissue tumor is more commonly found in individuals with pain, affecting deep-seated regions of the extremities, and commonly seen in the dorsal metatarsal space?

Clear cell sarcoma Signup and view all the answers

Which soft tissue tumor typically presents with a T1 homogenous and T2 heterogenous appearance on MRI scans?

Melanocytic sarcoma Signup and view all the answers

Which bone tumor is characterized by a nidus, shown as a central radiolucent area with a sclerotic rim on X-ray?

Osteoid osteoma Signup and view all the answers

Which malignant soft tissue tumor is associated with a 'Herring bone pattern' consisting of interlacing sheets of spindle-like fibroblasts?

Fibrosarcoma Signup and view all the answers

Which benign bone tumor typically affects the knee and hip, may present with central calcification, and causes pain relieved by ASPIRIN?

Osteoid osteoma Signup and view all the answers

Which malignant soft tissue tumor typically manifests as firm, painless papules on the trunk and upper extremities, extending to involve tendons, tendon sheath, and fascia?

Epithelioid sarcoma Signup and view all the answers

What is the notable feature found in the X-ray of an Osteoid Osteoma?

Calcification in the central area Signup and view all the answers

Which soft tissue tumor is more commonly found in deep-seated regions of the extremities and may manifest with calcifications and erosion of adjacent bone?

Clear cell sarcoma Signup and view all the answers

Which malignant tumor often presents with a 'Herring bone pattern' consisting of interlacing sheets of spindle-like fibroblasts?

Fibrosarcoma Signup and view all the answers

What is a common feature of Epithelioid Sarcoma on X-ray imaging?

Calcification and erosion of adjacent bone Signup and view all the answers

Which soft tissue tumor typically presents with homogenous T1 and heterogenous T2 findings on MRI scans?

Clear cell sarcoma Signup and view all the answers

Which benign lesion is likely to show transillumination with skin and usually appears painless unless it compresses a nerve?

Osteoid Osteoma Signup and view all the answers

Which malignant bone tumor is associated with variably calcified and multilobular calcifications on X-ray?

Chondrosarcoma Signup and view all the answers

Which benign bone tumor is characterized by a polypoid growth resembling a 'MUSHROOM' on X-ray?

Osteochondroma Signup and view all the answers

Which soft tissue tumor typically presents with a 'Herring bone pattern' consisting of interlacing sheets of spindle-like fibroblasts?

Chondrosarcoma Signup and view all the answers

What is a notable feature of Osteosarcoma on X-ray imaging?

CODMAN TRIANGLE Signup and view all the answers

Which benign lesion is known for containing tons of osteoid?

Osteoblastoma Signup and view all the answers

Which malignant soft tissue tumor is likely to contain a neural phenotype and may present with Homer Wright rosettes?

Ewing sarcoma Signup and view all the answers

Which benign bone tumor is more common in males, primarily affects individuals in their 30s, and is characterized by a ground glass appearance replacing the bone interior with fibro-osseous tissue?

Fibrous dysplasia Signup and view all the answers

Which benign bone tumor presents as a large lesion over 2cm, primarily found at the end of long bones in the metaphysis or shaft, and contains osteoid tissue intermixed with woven bone in a vascular connective tissue stroma?

Osteoblastoma Signup and view all the answers

Which benign tumor has a circumscribed lucent nidus with a zone of sclerosis, can metastasize to the lungs, and is known for its large eccentric, oval, radiolucent destructive lesion in the epiphysis?

Giant cell tumor Signup and view all the answers

Which benign bone tumor is associated with a spindle cell stroma producing immature bone, can rarely metastasize, and typically affects individuals aged 10-25 years?

Chondroblastoma Signup and view all the answers

Which benign bone tumor has an epiphyseal plate extending into the epiphysis, presents as a well-demarcated expansile oval lesion with thin sclerotic bone margin, and is derived from chondroblasts?

Chondroblastoma Signup and view all the answers

Which benign bone tumor produces high amounts of prostaglandins, typically affects individuals under 20 years of age, and is known for its characteristic night pain treated with aspirin?

Osteoid osteoma Signup and view all the answers

What is the purpose of an incisional biopsy?

For diagnosis Signup and view all the answers

Which type of biopsy is recommended when dealing with a larger lesion?

Core biopsy Signup and view all the answers

What is the key reason for avoiding necrotic and hemorrhagic areas in biopsy collection?

To ensure accurate pathological diagnosis Signup and view all the answers

In what type of biopsy is excision done for both diagnosis and treatment?

Excisional biopsy Signup and view all the answers

What is the recommended practice to avoid while handling biopsy samples?

Crush or squeeze the tissue Signup and view all the answers

Why is paraffin embedding a widely used procedure in surgical pathology?

To aid in microscopic study of tissues Signup and view all the answers

Which specimen is most appropriate for frozen sectioning based on the scenario provided?

Hard lymph node in the neck Signup and view all the answers

What is the purpose of fixation of tissue in surgical pathology?

To preserve the tissue architecture and cellular details Signup and view all the answers

Which of the following is a general rule for biopsy procedures?

Handle specimens gently to prevent damage Signup and view all the answers

What is a key advantage of using formalin for tissue fixation in surgical pathology?

Enhanced tissue softening for easier sectioning Signup and view all the answers

Which type of specimen collection method is least likely to be suitable for cytological diagnosis?

Punch biopsy Signup and view all the answers

In surgical pathology, which factor determines whether an excisional biopsy is preferred over an incisional biopsy?

Size and accessibility of the lesion Signup and view all the answers

What is the benefit of a frozen section over a permanent section?

Assesses adequacy of surgical margins Signup and view all the answers

Which statement about frozen section specimens is correct?

Labeling on the bag is not necessary Signup and view all the answers

In frozen section diagnosis, what does the presence or absence of ganglion cells in the large intestinal wall of Hirschsprung disease help assess?

Benign versus malignant lesion Signup and view all the answers

What is the primary aim of utilizing frozen sections for intraoperative consultation?

Assessing adequacy of surgical margins Signup and view all the answers

Why is the freezing cabinet used in the process of making thin sections for frozen sections?

To facilitate tissue sectioning Signup and view all the answers

What type of specimen is ideal for a frozen section?

< 1cm fresh tissue on ice Signup and view all the answers

Clear Cell Sarcoma and Malignant Melanocytic Sarcoma Quiz

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Questions and Answers

Which bone tumor is characterized by large lesions in the interior of diaphysis or metaphysis, with bone enlargement, focal periosteal reactions, and extension into soft tissue?

What is a notable feature of calcification in tumors of the foot/ankle?

Which malignant bone tumor typically has neuroectodermal cell origin and manifests as a mottled, moth-eaten destructive lesion with an 'onion skin' appearance?

In which age group is aggressive melanocytic sarcoma most commonly seen?

Which bone tumor is associated with a spindle cell stroma producing immature bone, and can have a 40% 5-year survival rate?

Which bone tumor has a 20% 5-year survival rate due to lung metastasis, and is more common in individuals over 20 years old?

Which tumor is characterized by clear cytoplasm and prominent nucleoli?

Which tumor is associated with a 'fish scale' pattern of calcification on X-ray?

Which tumor is characterized by a 'storiform' growth pattern and marked nuclear pleomorphism?

Which tumor is known for its aggressive behavior and high mitotic rate?

Which tumor type often presents with aggressive features such as ulceration and bleeding?

Which tumor is likely to show a 'salt and pepper' appearance on histological examination?

Which soft tissue tumor is more common in males, affects individuals in their 30s-40s, and is typically found in deep-seated regions of the extremities?

Which imaging modality may show a benign appearance with homogenous T1 and heterogenous T2 findings in melanocytic tumors?

Which soft tissue tumor typically presents with a 'Herring bone pattern' consisting of interlacing sheets of spindle-like fibroblasts?

In which age group is Epithelioid sarcoma most commonly found?

Which benign tumor, affecting the knee and hip, typically presents as asymptomatic but can cause pain relieved by ASPIRIN?

'Notable thing' found in the X-ray of which malignant tumor includes calcification and erosion of adjacent bone?

Which benign lesion is characterized by anechoic appearance on ultrasound and may be septate?

In which age group is neuroblastoma most commonly seen?

Which benign tumor is more common in individuals aged 50-70 and affects the synovial lining of fingers and toes?

Which benign lesion is likely to show transillumination with skin and is usually painless unless it compresses a nerve?

What is the most common primary malignant tumor in the body, characterized by plasma cells with lytic lesions and monoclonal gammopathy?

Which benign lesion typically occurs in individuals aged 40-60 and can be found anywhere fat persists in the body?

What is the characteristic MRI finding associated with hemangiomas in children?

Which tumor type is characterized by a blue-red blanchable papule and is commonly found under the nail bed?

What is the most common benign peripheral nerve sheath tumor?

Which soft tissue tumor typically affects individuals in the age range of 15-35 years and is found in periarticular regions like tendon sheaths and joint capsules?

What is the characteristic feature of synovial sarcomas on X-ray imaging?

Which tumor is characterized by cold sensitivity, known as Love's test, and is commonly found in the finger or toe nail beds?

Which bone tumor is characterized by a piece of bone that breaks off and deposits on the gravity-dependent edge of the tumor?

Which benign tumor has an oval, radiolucent appearance with a border of sclerosis resembling osteomyelitis?

Which malignant bone tumor may mimic osteomyelitis and present with pain, swelling, warmth, fever, and increased ESR?

Which malignant bone tumor is associated with periosteal reaction leading to an 'onion skin' appearance and a soft tissue mass?

Which malignant bone tumor has a matrix in the periosteum and develops in places of active growth like long bones of the knee?

Which malignant bone tumor is the most common malignant bone tumor of the foot/ankle with bubble radiolucency, calcifications, and calcifications?

Which tumor type presents with a neural phenotype, identical chromosome translocation, and is classified as an UNDIFFERENTIATED small round blue tumor?

Which benign bone tumor may appear as an asymptomatic incidental finding on x-ray, typically affecting the metaphysis of the distal femur and proximal tibia, and is known for having scalloped margins?

In which type of tumor would one likely observe Homer Wright rosettes and a neural phenotype?

Which benign bone tumor is characterized by radiolucency in the epiphysis of long bones such as the distal radius and knee, and is often associated with arthritis-like symptoms?

Which bone tumor, benign in most cases, can present with curvilinear spicules of immature woven bone surrounded by fibroblastic proliferation, and is typically found anywhere in the long bones, jaw, or skull?

Which soft tissue tumor is more commonly found in individuals with pain, affecting deep-seated regions of the extremities, and commonly seen in the dorsal metatarsal space?

Which soft tissue tumor typically presents with a T1 homogenous and T2 heterogenous appearance on MRI scans?

Which bone tumor is characterized by a nidus, shown as a central radiolucent area with a sclerotic rim on X-ray?

Which malignant soft tissue tumor is associated with a 'Herring bone pattern' consisting of interlacing sheets of spindle-like fibroblasts?

Which benign bone tumor typically affects the knee and hip, may present with central calcification, and causes pain relieved by ASPIRIN?

Which malignant soft tissue tumor typically manifests as firm, painless papules on the trunk and upper extremities, extending to involve tendons, tendon sheath, and fascia?

What is the notable feature found in the X-ray of an Osteoid Osteoma?

Which soft tissue tumor is more commonly found in deep-seated regions of the extremities and may manifest with calcifications and erosion of adjacent bone?

Which malignant tumor often presents with a 'Herring bone pattern' consisting of interlacing sheets of spindle-like fibroblasts?

What is a common feature of Epithelioid Sarcoma on X-ray imaging?

Which soft tissue tumor typically presents with homogenous T1 and heterogenous T2 findings on MRI scans?

Which benign lesion is likely to show transillumination with skin and usually appears painless unless it compresses a nerve?

Which malignant bone tumor is associated with variably calcified and multilobular calcifications on X-ray?

Which benign bone tumor is characterized by a polypoid growth resembling a 'MUSHROOM' on X-ray?

Which soft tissue tumor typically presents with a 'Herring bone pattern' consisting of interlacing sheets of spindle-like fibroblasts?

What is a notable feature of Osteosarcoma on X-ray imaging?

Which benign lesion is known for containing tons of osteoid?

Which malignant soft tissue tumor is likely to contain a neural phenotype and may present with Homer Wright rosettes?

Which benign bone tumor is more common in males, primarily affects individuals in their 30s, and is characterized by a ground glass appearance replacing the bone interior with fibro-osseous tissue?

Which benign bone tumor presents as a large lesion over 2cm, primarily found at the end of long bones in the metaphysis or shaft, and contains osteoid tissue intermixed with woven bone in a vascular connective tissue stroma?

Which benign tumor has a circumscribed lucent nidus with a zone of sclerosis, can metastasize to the lungs, and is known for its large eccentric, oval, radiolucent destructive lesion in the epiphysis?

Which benign bone tumor is associated with a spindle cell stroma producing immature bone, can rarely metastasize, and typically affects individuals aged 10-25 years?

Which benign bone tumor has an epiphyseal plate extending into the epiphysis, presents as a well-demarcated expansile oval lesion with thin sclerotic bone margin, and is derived from chondroblasts?

Which benign bone tumor produces high amounts of prostaglandins, typically affects individuals under 20 years of age, and is known for its characteristic night pain treated with aspirin?

What is the purpose of an incisional biopsy?

Which type of biopsy is recommended when dealing with a larger lesion?

What is the key reason for avoiding necrotic and hemorrhagic areas in biopsy collection?

In what type of biopsy is excision done for both diagnosis and treatment?

What is the recommended practice to avoid while handling biopsy samples?

Why is paraffin embedding a widely used procedure in surgical pathology?

Which specimen is most appropriate for frozen sectioning based on the scenario provided?

What is the purpose of fixation of tissue in surgical pathology?

Which of the following is a general rule for biopsy procedures?

What is a key advantage of using formalin for tissue fixation in surgical pathology?

Which type of specimen collection method is least likely to be suitable for cytological diagnosis?

In surgical pathology, which factor determines whether an excisional biopsy is preferred over an incisional biopsy?