Podcast
Questions and Answers
Which type of sarcoma is typically associated with a simple karyotype and a monomorphic microscopic appearance?
Which type of sarcoma is typically associated with a simple karyotype and a monomorphic microscopic appearance?
- Undifferentiated pleomorphic sarcoma
- Liposarcoma
- Ewing sarcoma (correct)
- Leiomyosarcoma
What is the approximate percentage of sarcomas that have a complex karyotype with multiple chromosomal gains and losses?
What is the approximate percentage of sarcomas that have a complex karyotype with multiple chromosomal gains and losses?
- 15-20%
- 80-85% (correct)
- 90-95%
- 50-60%
Which of the following is NOT a feature of sarcomas with a complex karyotype?
Which of the following is NOT a feature of sarcomas with a complex karyotype?
- Microscopically pleomorphic
- Demonstrate multiple chromosomal gains and losses
- More common in children (correct)
- Aneuploid or polyploid
Which of the following is a potential molecular target for diagnosis and therapy of sarcomas?
Which of the following is a potential molecular target for diagnosis and therapy of sarcomas?
What is the main prognostic factor for sarcomas, according to the information provided?
What is the main prognostic factor for sarcomas, according to the information provided?
Which parameter is used to grade tumors based on differentiation, mitoses, and necrosis?
Which parameter is used to grade tumors based on differentiation, mitoses, and necrosis?
What is the most common subtype of benign tumors of fat in adults?
What is the most common subtype of benign tumors of fat in adults?
What is a common presentation of lipomas?
What is a common presentation of lipomas?
Where do liposarcomas typically occur?
Where do liposarcomas typically occur?
Which parameter is used to stage tumors according to their size?
Which parameter is used to stage tumors according to their size?
Which of the following is NOT a tumor of adipose tissue?
Which of the following is NOT a tumor of adipose tissue?
Which type of sarcoma is commonly seen in children?
Which type of sarcoma is commonly seen in children?
Which of the following tumors is associated with human herpesvirus 8 (HHV8) infection?
Which of the following tumors is associated with human herpesvirus 8 (HHV8) infection?
Which of the following genetic syndromes is associated with neurofibroma and malignant schwannoma?
Which of the following genetic syndromes is associated with neurofibroma and malignant schwannoma?
Which of the following is the most characteristic feature of well-differentiated liposarcoma/atypical lipomatous tumor?
Which of the following is the most characteristic feature of well-differentiated liposarcoma/atypical lipomatous tumor?
Which of the following statements about soft tissue tumors is correct?
Which of the following statements about soft tissue tumors is correct?
Which of the following is the most characteristic genetic alteration seen in myxoid liposarcoma?
Which of the following is the most characteristic genetic alteration seen in myxoid liposarcoma?
Which of the following liposarcoma subtypes has the worst prognosis?
Which of the following liposarcoma subtypes has the worst prognosis?
What is the typical location of well-differentiated liposarcoma and dedifferentiated liposarcoma?
What is the typical location of well-differentiated liposarcoma and dedifferentiated liposarcoma?
What is the most characteristic feature of nodular fasciitis?
What is the most characteristic feature of nodular fasciitis?
Which type of fibromatosis is typically found in the abdomen, abdominal wall, and muscles of the trunk and extremities?
Which type of fibromatosis is typically found in the abdomen, abdominal wall, and muscles of the trunk and extremities?
What is the typical histological appearance of fibromatoses?
What is the typical histological appearance of fibromatoses?
Which type of fibromatosis is associated with Dupuytren contracture and Peyronie disease?
Which type of fibromatosis is associated with Dupuytren contracture and Peyronie disease?
What is the typical clinical presentation of fibromatoses?
What is the typical clinical presentation of fibromatoses?
Which genetic mutations are often found in deep fibromatoses (desmoid tumors)?
Which genetic mutations are often found in deep fibromatoses (desmoid tumors)?
