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Questions and Answers
Who isolated the Ergot alkaloid Ergotamine in 1918?
Who isolated the Ergot alkaloid Ergotamine in 1918?
- Albert Hoffman
- Jacobs and Craig
- Arthur Stoll (correct)
- Sandoz
What is the primary effect of chronic consumption of small amounts of ergot alkaloids?
What is the primary effect of chronic consumption of small amounts of ergot alkaloids?
- Severe twisting of the body and neck in pain
- Uterine and vascular contraction (correct)
- Hallucinations and convulsions
- Headache and vertigo
Which alkaloid derivative did Albert Hoffman prepare as a hemostatic drug for obstetrics?
Which alkaloid derivative did Albert Hoffman prepare as a hemostatic drug for obstetrics?
- Ergotoxine
- Ergotamine
- Lysergic acid
- Ergonovine (correct)
What is the primary symptom of convulsive ergotism?
What is the primary symptom of convulsive ergotism?
What are the consequences of acute consumption of large amounts of ergot alkaloids?
What are the consequences of acute consumption of large amounts of ergot alkaloids?
Study Notes
Isolation of Ergotamine
- Ergotamine, an important ergot alkaloid, was isolated in 1918 by Dr. Arthur Stoll.
Effects of Chronic Ergot Alkaloids Consumption
- Chronic consumption of small amounts of ergot alkaloids primarily leads to vasoconstriction, which can cause peripheral circulation issues.
Albert Hoffman's Hemostatic Drug
- Albert Hoffman prepared the ergot alkaloid derivative ergonovine as a hemostatic drug specifically for use in obstetrics.
Primary Symptom of Convulsive Ergotism
- The primary symptom of convulsive ergotism is severe muscle spasms, often accompanied by headaches and mental disturbances.
Consequences of Acute Ergot Alkaloids Consumption
- Acute consumption of large amounts of ergot alkaloids can result in poisoning, leading to symptoms such as nausea, vomiting, and potentially severe conditions like gangrene due to extreme vasoconstriction.
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Description
Test your knowledge of fungal toxins with this quiz on Claviceps purpurea, a fungus known for containing ergotoxine and related alkaloids. Learn about the effects of chronic and acute consumption of these toxins and their impact on smooth muscle, uterine contraction, and vascular health.
