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Questions and Answers
Which enzyme is responsible for oxidizing xenobiotics in the liver, kidney, and intestine?
Which enzyme is responsible for oxidizing xenobiotics in the liver, kidney, and intestine?
- Aldehyde dehydrogenase
- Flavin-containing monooxygenases (FMO) (correct)
- Cytochrome P450
- Glutathione S-transferase (GST)
Which cellular compartment contains the microsomal enzymes responsible for oxidizing xenobiotics?
Which cellular compartment contains the microsomal enzymes responsible for oxidizing xenobiotics?
- Endoplasmic reticulum (ER) membrane (correct)
- Mitochondria
- Lysosomes
- Golgi apparatus
Which cofactor is required by the oxidizing phase I enzymes to carry out the oxidation of xenobiotics?
Which cofactor is required by the oxidizing phase I enzymes to carry out the oxidation of xenobiotics?
- FAD
- NADPH (correct)
- ATP
- NADH
Which enzyme is located in the mitochondrial outer membrane and is involved in the oxidation of both endogenous and xenobiotic substrates?
Which enzyme is located in the mitochondrial outer membrane and is involved in the oxidation of both endogenous and xenobiotic substrates?
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Which prosthetic group is required by the oxidizing phase I enzymes to carry out their oxidation reactions?
Which prosthetic group is required by the oxidizing phase I enzymes to carry out their oxidation reactions?
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Which forms of Monoamine Oxidases (MAOs) are involved in the oxidation of primary amines?
Which forms of Monoamine Oxidases (MAOs) are involved in the oxidation of primary amines?
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