6 Questions
Which enzyme is responsible for oxidizing xenobiotics in the liver, kidney, and intestine?
Flavin-containing monooxygenases (FMO)
Which cellular compartment contains the microsomal enzymes responsible for oxidizing xenobiotics?
Endoplasmic reticulum (ER) membrane
Which cofactor is required by the oxidizing phase I enzymes to carry out the oxidation of xenobiotics?
NADPH
Which enzyme is located in the mitochondrial outer membrane and is involved in the oxidation of both endogenous and xenobiotic substrates?
Monoamine oxidase (MAO)
Which prosthetic group is required by the oxidizing phase I enzymes to carry out their oxidation reactions?
FAD
Which forms of Monoamine Oxidases (MAOs) are involved in the oxidation of primary amines?
Form A and Form B
Test your knowledge on Oxidizing Phase I Enzymes: Flavin-containing monooxygenases (FMO) in the liver, kidney, and intestine. Learn about their role in oxidizing xenobiotics at N, S, and P to form Noxides, sulfoxides, and phosphites. Explore their association with the microsomal ER membrane and the use of NADPH and O2 in the process.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
