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Questions and Answers

Which enzyme is responsible for oxidizing xenobiotics in the liver, kidney, and intestine?

  • Aldehyde dehydrogenase
  • Flavin-containing monooxygenases (FMO) (correct)
  • Cytochrome P450
  • Glutathione S-transferase (GST)
  • Which cellular compartment contains the microsomal enzymes responsible for oxidizing xenobiotics?

  • Endoplasmic reticulum (ER) membrane (correct)
  • Mitochondria
  • Lysosomes
  • Golgi apparatus
  • Which cofactor is required by the oxidizing phase I enzymes to carry out the oxidation of xenobiotics?

  • FAD
  • NADPH (correct)
  • ATP
  • NADH
  • Which enzyme is located in the mitochondrial outer membrane and is involved in the oxidation of both endogenous and xenobiotic substrates?

    <p>Monoamine oxidase (MAO)</p> Signup and view all the answers

    Which prosthetic group is required by the oxidizing phase I enzymes to carry out their oxidation reactions?

    <p>FAD</p> Signup and view all the answers

    Which forms of Monoamine Oxidases (MAOs) are involved in the oxidation of primary amines?

    <p>Form A and Form B</p> Signup and view all the answers

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