CKD Lifestyle and Dietary Measures Quiz

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ACE inhibitors and ARBs are not recommended in CKD due to their potential to?

Increase GFR (correct)

Promote sclerosis of the glomerular basement membrane

Decrease proteinuria

Raise glomerular hydrostatic pressure

What is the effect of dilation of the efferent arteriole?

Increased glomerular hydrostatic pressure

Increased glomerular filtration rate

Decreased proteinuria

Decreased glomerular hydrostatic pressure (correct)

Which statement best describes the impact of ACE inhibitors and ARBs on GFR?

They reduce GFR by constricting the afferent arteriole

They increase GFR by dilating the efferent arteriole

They have no effect on GFR

They decrease GFR by constricting the efferent arteriole (correct)

What role do ACE inhibitors play in preventing sclerosis of the glomerular basement membrane?

They prevent sclerosis by decreasing proteinuria Signup and view all the answers

In CKD, ACE inhibitors are indicated for which condition?

Metabolic acidosis Signup and view all the answers

What is the mechanism by which ACE inhibitors can lead to hypotension in patients with chronic kidney disease (CKD)?

ACE inhibitors decrease angiotensin II levels, leading to less vasoconstriction and decreased total peripheral vascular resistance Signup and view all the answers

Which of the following is a mechanism by which ACE inhibitors may be nephroprotective in patients with CKD?

Increasing bradykinin levels, leading to increased vasoconstriction of the efferent arteriole Signup and view all the answers

Which of the following is a key reason why ACE inhibitors (or ARBs) are considered first-line anti-hypertensive agents in patients with CKD?

They decrease angiotensin II levels, leading to decreased vasoconstriction and lower blood pressure Signup and view all the answers

Which of the following is a potential adverse effect of ACE inhibitors in patients with CKD?

Increased bradykinin levels leading to increased vasodilation and hypotension Signup and view all the answers

How do ARBs differ from ACE inhibitors in their mechanism of action in patients with CKD?

ARBs block the angiotensin II receptor, while ACE inhibitors block the conversion of angiotensin I to angiotensin II Signup and view all the answers

What is the primary rationale for using ACE inhibitors (or ARBs) as first-line anti-hypertensive agents in patients with CKD?

They decrease angiotensin II levels, leading to decreased vasoconstriction and lower blood pressure Signup and view all the answers

Which of the following is a common side effect of Angiotensin-receptor blockers (ARBs)?

Hyperkalemia Signup and view all the answers

What is the primary mechanism of action of ARBs?

Blocks the angiotensin II AT1 receptor Signup and view all the answers

Why are ACE inhibitors or ARBs considered first-line anti-hypertensive agents in chronic kidney disease (CKD)?

They have nephroprotective properties and treat hypertension Signup and view all the answers

What is the primary adverse effect associated with ACE inhibitors?

Cough Signup and view all the answers

Which of the following is a contraindication for using Angiotensin-receptor blockers (ARBs)?

Allergy Signup and view all the answers

How do ARBs contribute to nephroprotection in chronic kidney disease?

By reducing intraglomerular pressure Signup and view all the answers

CKD Lifestyle and Dietary Measures Quiz

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