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Questions and Answers
What is formed when the acetyl group from acetyl CoA combines with oxaloacetate?
What is formed when the acetyl group from acetyl CoA combines with oxaloacetate?
What compound is produced from the oxidation of isocitrate?
What compound is produced from the oxidation of isocitrate?
What happens to the CoA group in succinyl CoA during the citric acid cycle?
What happens to the CoA group in succinyl CoA during the citric acid cycle?
Which of the following steps leads to the formation of FADH2?
Which of the following steps leads to the formation of FADH2?
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What is regenerated at the end of the citric acid cycle?
What is regenerated at the end of the citric acid cycle?
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Study Notes
Citric Acid Cycle (Krebs Cycle)
- Acetyl CoA combines with oxaloacetate to form citrate (a 6-carbon molecule).
- Citrate loses two carbons as CO2 in subsequent reactions.
- Citrate is converted to isocitrate.
- Isocitrate is oxidized, releasing CO2 and producing alpha-ketoglutarate (a 5-carbon molecule).
- Alpha-ketoglutarate is oxidized, yielding another NADH and CO2. This reaction results in a 4-carbon molecule, succinyl CoA.
- Succinyl CoA loses its CoA group. The released energy is used to produce ATP.
- Succinate is oxidized to fumarate.
- During this oxidation, two electrons and protons are transferred to FAD, producing FADH2.
- Water is added to fumarate to form malate.
- Finally, malate is oxidized to regenerate oxaloacetate. NAD+ is reduced to NADH during this step.
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Description
Test your knowledge on the Citric Acid Cycle, also known as the Krebs Cycle. This quiz covers the key steps and components involved in this crucial metabolic pathway. Dive in to understand how energy is produced through the transformation of acetyl CoA and the regeneration of oxaloacetate.
