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Citric Acid Cycle Overview

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30 Questions

What is the role of PFK1 in glycolysis?

Controlling the irreversible step of glycolysis

Which molecules inhibit PFK1 in glycolysis?

Citrate and ATP

How does AMP affect PFK1 activity in glycolysis?

Activates PFK1

What is the function of insulin in blood sugar regulation?

Stimulate glucose uptake by cells

How do hexokinase enzymes contribute to glycolysis?

Control hexose phosphorylation

Which molecules signal PFK1 to slow down glycolysis when cellular energy is abundant?

ATP and citrate

What is the primary function of the citric acid cycle?

To further oxidize organic fuel

What molecules carry high-energy electrons to the electron transport chain during cellular respiration?

NADH and FADH₂

Which scientist is honored by the alternative name 'Krebs cycle' for the citric acid cycle?

Hans Krebs

What is the main role of the electron transport chain in cellular respiration?

Create a proton gradient across the membrane

How is acetyl CoA formed during cellular respiration?

By binding with two-carbon fragments and CoA

Which process in cellular respiration results in the production of NADH?

Glycolysis

What is the role of insulin in the body?

Signal cells to absorb glucose from the bloodstream

Which hormone is responsible for converting stored glycogen back into glucose?

Glucagon

In Diabetes Mellitus, what happens when insulin isn't functioning properly?

Glucose struggles to enter cells

What type of diabetes involves the body's immune system attacking insulin-producing cells?

Type 1 diabetes

How does glucagon help ensure a steady supply of energy to other cells in the body?

Converting stored glycogen into glucose

What is the primary consequence of abnormal carbohydrate metabolism in Diabetes Mellitus?

Elevated blood glucose levels

What is a common symptom of type 2 diabetes according to the text?

Blurred vision

Why might unintended weight loss occur in individuals with diabetes?

Cells cannot effectively utilize glucose

How do high blood sugar levels affect blood vessels and organs?

Cause osmotic imbalances

What is a key management strategy for diabetes according to the text?

Regular exercise

What are the long-term consequences of chronic high blood sugar levels?

Kidney damage and neuropathy

Why does elevated blood sugar levels in diabetes lead to cellular hunger?

Ineffective glucose transport into cells

What is the main reason for the development of Type 1 diabetes?

Genetic and environmental factors

Which age group is Type 1 diabetes most likely to affect?

Children and adolescents

What distinguishes Type 1 diabetes from Type 2 diabetes in terms of insulin production?

No insulin production due to destroyed beta cells

What is the primary cause of Type 2 diabetes?

Insulin resistance

What do later stages of Type 2 diabetes involve regarding insulin production?

Insulin production may decrease

How does Type 2 diabetes differ from Type 1 diabetes in terms of prevalence?

>90% of diabetics have Type 2 diabetes

This quiz covers an overview of the Citric Acid Cycle, also known as the Krebs Cycle, highlighting the key steps and functions involved. Topics include the formation of acetyl CoA, production of NADH, and ATP generation through substrate-level phosphorylation.

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