Citric Acid Cycle and Cellular Respiration
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Questions and Answers

What is gluconeogenesis?

  • The breakdown of glucose
  • The making of glucose from pyruvate (correct)
  • The conversion of glucose to lactate
  • The making of glycogen
  • Which molecule combines with a four-carbon chain called oxaloacetate in the citric acid cycle?

  • Citrate
  • Fumarate
  • Acetyl-CoA (correct)
  • Malate
  • What type of reaction is the link reaction?

  • Oxidative decarboxylation (correct)
  • Reductive carboxylation
  • Isomerisation
  • Hydrolysis
  • What is generated in Step 3 of the TCA cycle?

    <p>Carbon dioxide and NADH</p> Signup and view all the answers

    Which enzyme is involved in step 5 of the TCA cycle?

    <p>Ligase</p> Signup and view all the answers

    What is regenerated in step 6 of the TCA cycle?

    <p>Four-carbon chain</p> Signup and view all the answers

    Which molecule is involved in the preparation step of the citric acid cycle?

    <p>Pyruvate</p> Signup and view all the answers

    Which of the following is a product of the citric acid cycle?

    <p>NADH, FADH2, and GTP</p> Signup and view all the answers

    What happens in step 8 of the TCA cycle?

    <p>Remaking of oxaloacetate</p> Signup and view all the answers

    Which term describes the removal of electrons from carbon?

    <p>Oxidation</p> Signup and view all the answers

    Study Notes

    Citric Acid Cycle

    • Gluconeogenesis is the process of generating glucose from pyruvate.
    • Glycogen synthesis is the process of generating glycogen.
    • Citric acid cycle generates 150 kJ/mole of ATP, which can occur in the presence or absence of oxygen.

    Preparation Step (Step 0)

    • Breaks down a 3-carbon chain, releasing 1 molecule of carbon dioxide, to generate a 2-carbon chain that enters the cycle.
    • The 2-carbon chain combines with a 4-carbon chain called oxaloacetate to form citric acid, creating a 6-carbon molecule.

    TCA Cycle: 8 Steps + Preparation

    • Step 1: Pyruvate is converted to Acetyl-CoA, releasing CO₂ and generating NADH.
    • Step 2: Citrate is formed from Acetyl-CoA.
    • Step 3: Isocitrate is formed, generating NADH.
    • Step 4: α-Ketoglutarate is formed, releasing CO₂ and generating NADH.
    • Step 5: GTP is generated through substrate-level phosphorylation, converting GDP + Pi to GTP.
    • Step 6: The enzyme oxidoreductase generates more NADH and FADH2.
    • Step 7: Involves a redox reaction and a ligase reaction, making or breaking double carbon bonds.
    • Step 8: Oxaloacetate is regenerated, completing the cycle.

    Key Molecules and Processes

    • NADH and FADH2 are generated in the citric acid cycle, which will be used to generate more ATP later.
    • Redox reactions, such as oxidative decarboxylation, occur throughout the cycle.
    • The citric acid cycle is a critical step in cellular respiration, breaking down carbon chains and generating energy.

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    Description

    Learn about the citric acid cycle, gluconeogenesis, glycogenisis, and cellular respiration processes, including the breakdown of molecules and ATP energy production.

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