Cirrhosis Pathophysiology and Causes

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18 Questions

The most common causes of cirrhosis are chronic hepatitis C, alcoholism, ______, and nonalcoholic steatohepatitis (NASH).

nonalcoholic fatty liver disease (NAFLD)

Cirrhosis leads to ______ due to obstruction to flow in the portal vein.

portal hypertension

Ascites is the accumulation of fluid in the peritoneal cavity that results from ______ of the hepatic capillaries.

venous congestion

Bleeding esophageal varices are fragile, thin-walled, distended esophageal veins that become ______ and rupture.

irritated

Decreased synthesis of bile fats in the liver prevents the absorption of ______-soluble vitamins.

fat

Without vitamin K and clotting factors II, VII, IX, and X, the client is prone to ______ and easy bruising.

bleeding

Jaundice occurs because the liver is unable to metabolize ______

bilirubin

Portal systemic encephalopathy is caused by failure of the diseased liver to detoxify ______ agents such as ammonia

neurotoxic

Hepatorenal syndrome is characterized by a sudden decrease in ______ output

urinary

Serum ______ is decreased in diagnostic evaluation

albumin

Serum ______ is increased in diagnostic evaluation

bilirubin

Liver ______ is a confirmatory diagnostic test

biopsy

Pathophysiology Appendix kinked or occluded by fecalith, lymphoid ______, foreign bodies, or tumors

hyperplasia

Diagnostic Evaluation Pregnancy test – rule out ______ pregnancy

ectopic

Complications ______ or Perforation

Gangrene

Complications Peritonitis ______ formation

Abscess

Management Prevent or treat surgical site ______ – administer antibiotic therapy

infection

Management Attain optimal ______ – assess return of bowel sounds and passing of flatus

nutrition

Learn about the causes and pathophysiology of cirrhosis, including chronic hepatitis C, alcoholism, NAFLD, and NASH. Explore the process of injury to hepatic elements, initiation of inflammatory response, destruction of liver cells, and formation of fibrous scar tissue.

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