23.4 Circadian Timing System and Pharmacology

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What part of the body receives light-dark cycle information from the environment?

Hypothalamus

What is the primary reason for the time of day-dependent absorption of drugs?

Different rates of gastric emptying

What is the primary function of Phase 1 metabolic reactions?

Catabolic reactions

Why does asthma typically occur at night?

Reduced airway calibre

What is the optimal time to administer theophylline medication for asthma?

Evening

What is the potential application of A1/A2a agonists in circadian rhythm regulation?

Shifting the clock

Test your knowledge on the Circadian Timing System (CTS) and its effects on pharmacology, including the role of the SCN, time-dependent drug absorption, and distribution and metabolism.

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