23.3 Circadian Rhythm Disruption and Cancer

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What is the definition of chronodisruption?

A relevant disturbance of the circadian organization of physiology, endocrinology, metabolism, and behavior

What is the effect of nightshift work on the risk of metabolic syndrome and diabetes?

It increases the risk

What is the relationship between the circadian clock and the cell cycle?

The circadian clock influences cell cycle synchronization

What is the effect of circadian disruption on cancer cells?

<p>It accelerates cell division</p> Signup and view all the answers

What is the relationship between the circadian clock and cancer?

<p>Shift work that involves circadian disruption is probably carcinogenic to humans</p> Signup and view all the answers

What is the effect of social cues, activity, light, and meal timing on the circadian rhythm?

<p>They can affect the circadian rhythm</p> Signup and view all the answers

What is a probable consequence of shift work that involves circadian disruption?

<p>It is probably carcinogenic to humans</p> Signup and view all the answers

What is the role of melatonin in the context of chronodisruption?

<p>It is a key biological intermediary between light and the development of cancers</p> Signup and view all the answers

Why do cancer cells want to divide faster than the circadian clock allows?

<p>To overcome the regulation of the cell cycle by the circadian clock</p> Signup and view all the answers

What is the consequence of the circadian clock and cell cycle being out of sync in cancer cells?

<p>Development of certain cancers</p> Signup and view all the answers

What is the pattern of the cell cycle in relation to the circadian phases?

<p>The cell cycle follows the circadian phases</p> Signup and view all the answers

What is the effect of nightshift work on the risk of certain diseases?

<p>It increases the risk of certain cancers</p> Signup and view all the answers

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