Chronic Obstructive Pulmonary Disease (COPD) Definitions

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Questions and Answers

Which of the following is NOT a common genetic risk factor for COPD?

  • Genetic mutations leading to α-1 antitrypsin deficiency
  • Genetic mutations affecting serine proteases
  • Genetic mutations affecting inflammatory responses
  • Genetic mutations leading to hereditary deficiency of elastin (correct)

What is a major circulating inhibitor of serine proteases implicated in COPD?

  • Neutrophils
  • Elastin
  • α-1 antitrypsin (correct)
  • Macrophages

Which of the following is a characteristic feature of protease-mediated destruction in COPD?

  • Decreased neutrophils
  • Peribronchiolar fibrosis (correct)
  • Increased lymphocytes
  • Reduced macrophages

What structural changes occur in the lungs in COPD due to an imbalance between proteases and antiproteases?

<p>Emphysema (C)</p> Signup and view all the answers

Which of the following is NOT a common pathophysiological feature of COPD?

<p>Decreased mucus hypersecretion (A)</p> Signup and view all the answers

What is the main characteristic that distinguishes Chronic Bronchitis from Emphysema in COPD?

<p>Presence of cough and sputum production (C)</p> Signup and view all the answers

What defines the duration criteria for Chronic Bronchitis as part of COPD diagnosis?

<p>At least 3 months in each of two consecutive years (A)</p> Signup and view all the answers

Which statement accurately describes the role of cigarette smoking in the development of COPD?

<p>Cigarette smoking is a key environmental risk factor for COPD. (A)</p> Signup and view all the answers

How are abnormalities of the airways and alveoli in COPD manifested?

<p>Resulting in persistent, often progressive airflow obstruction (A)</p> Signup and view all the answers

What defines Emphysema pathologically in the context of COPD?

<p>Permanent enlargement of airspaces with wall destruction (A)</p> Signup and view all the answers

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